[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628704":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":38,"responsibleParty":48,"collaborators":52,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":25,"enrollmentInfo":65,"targetDuration":25,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":41,"whyStopped":25,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"University Hospital Bispebjerg and Frederiksberg","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control","ACTIVE_COMPARATOR","The control arm will continue usual management (best medical treatment) of their PD and other potentiel comorbidities at the discretion of their regular physician and other health providers. Enrollment in this study will not influence any clinical decisions or potential changes in management.",[13],"Other: Usual Care",{"label":15,"type":16,"description":17,"interventionNames":18},"Intervention","EXPERIMENTAL","The intervention arm will receive 3 weekly 1-hour sessions of multi-modal training over the course of 12 weeks, totaling 36 sessions, in addition to usual management (best medical treatment). As with the control arm, any clinical decisions or potential changes in management will not be influenced be enrollment in this study.",[19],"Other: Motor-cognitive exercise",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Motor-cognitive exercise","3 weekly 1-hour sessions of motor-cognitive exercise. Each 1-hour session will be multi-modal with 20 minutes of dynamic balance training, 20 minutes of dual-task exercises while treadmill walking and 20 minutes of lower body strength training with leg press. Detailed protocols for the exercises will be published along with results.",[15],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Usual Care","Best medical treatment: usual management of participants' PD and other potential comorbidities at the discretion of their regular physician and other health providers.",[9],[31,36],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Annemette Løkkegaard, MD, PhD","CONTACT","+45 38 63 52 48","annemette.loekkegaard@regionh.dk",{"name":37,"role":33,"phone":25,"phoneExt":25,"email":25},"Løkkegaard",[39],{"facility":40,"status":41,"city":42,"state":25,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":25,"geoPoint":25,"contacts":46},"Department of Neurology, Bispebjerg and Frederiksberg Hospital","RECRUITING","Copenhagen NV","2400","Denmark","DK",[47],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Annemette Lokkegaard","MD, PhD, Ass. Professor, Consultant Neurologist",[53],{"name":54,"class":6},"Copenhagen Trial Unit, Center for Clinical Intervention Research","100628704","motor-and-cognitive-exercise-in-parkinsons-disease-100628704",false,"NCT07465107","Motor and Cognitive Exercise in Parkinson's Disease.","Motor and Cognitive Exercise in Parkinson's Disease. A Feasibility Randomized Clinical Trial","Ex-Park","Inclusion Criteria:\n\n* Diagnosis of PD according to MDS-PD criteria\n* Aged ≥ 18 years\n* Informed consent\n* PD symptoms ≥ 4 years\n* Independent gait\n\nExclusion Criteria:\n\n* Diagnosis of PD Dementia according to the MDS-PD Dementia criteria","ALL","18 Years",{"count":66,"type":67},48,"ESTIMATED","INTERVENTIONAL",[70],"NA","The aim of this study is to examine the effects of a specialized multi-modal intervention in patients with moderate to advanced Parkinson's disease (PD). The hypothesis is that a specialized motor- and cognitive exercise program in addition to usual care can improve gait and balance better than usual care alone.\n\n48 patients with PD and a symptom duration of 4 or more years will be randomized 1:1 to either a control arm or to an intervention arm. The control arm will have usual management of their PD. The intervention arm will receive exercises aimed at both motor and cognitive impairments of PD over the course of 12 weeks.\n\nThe study has been designed in partnership with the Copenhagen Trial Unit (CTU), Copenhagen Univeristy Hospital, to ensure both internal and external validity. To increase reproducibility, detailed protocols for all training modalities will be shared along with the study results.\n\nThis study is a feasibility study with the intention of a following international multi-center study to corroborate the results. Both feasibility outcomes for the intervention itself and clinical outcomes for the participants will be published.",[73],"Parkinson Disease (PD)",[75,76,77,78,79,80,81,82],"Parkinson Disease","Exercise Therapy","Gait","Balance","Motor-cognitive training","Dual-task","Neurological Rehabilitation","Psychomotor Performance","2026-03-06",{"date":85,"type":86},"2026-03-11","ACTUAL",{"date":88,"type":86},"2025-03-26",{"date":90,"type":67},"2027-02-14",{"name":50,"class":6},1]