[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100526914":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":42,"responsibleParty":71,"collaborators":25,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":81,"sex":82,"minAge":83,"maxAge":25,"enrollmentInfo":84,"targetDuration":25,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":25,"overallStatus":45,"whyStopped":25,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Hôpital le Vinatier","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"active stimulation group: 20 participants with aphantasia will receive a session of active HD-tDCS","EXPERIMENTAL","Participants will receive a session of active HD-tDCS at a current intensity of 4 mA for a duration of 15min. The placement of electrodes will be determined to specifically target the primary motor cortex (4 x 1 montage with the anode over C4). During the stimulation, participants will be engaged in a mental training task (sequential finger tapping-task).",[13],"Procedure: High-definition transcranial direct current (HD-tDCS), active condition",{"label":15,"type":16,"description":17,"interventionNames":18},"placebo stimulation group: 20 participants with aphantasia will receive a session of sham HD-tDCS","PLACEBO_COMPARATOR","High-definition transcranial direct current (HD-tDCS), sham condition. Participants will receive a session of sham HD-tDCS, which will be delivered following the same procedures as active HD-tDCS but the intensity of the current will be set at 4mA during the 30 first seconds at the beginning of the 15-min period of the stimulation, and equal to 0 mA for the reminding period of stimulation to simulate the tingling sensation often experienced by individuals during active stimulation.\n\nThe placement of electrodes will be determined to specifically target the primary motor cortex (4 x 1 montage with the anode over C4). During the stimulation, participants will be engaged in a mental training task (sequential finger tapping-task).",[19],"Procedure: High-definition transcranial direct current (HD-tDCS), sham condition",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"PROCEDURE","High-definition transcranial direct current (HD-tDCS), active condition",[9],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"High-definition transcranial direct current (HD-tDCS), sham condition","Participants will receive a session of sham HD-tDCS, which will be delivered following the same procedures as active HD-tDCS but the intensity of the current will be set at 4mA during the 30 first seconds at the beginning of the 15-min period of the stimulation, and equal to 0 mA for the reminding period of stimulation to simulate the tingling sensation often experienced by individuals during active stimulation.\n\nThe placement of electrodes will be determined to specifically target the primary motor cortex (4 x 1 montage with the anode over C4). During the stimulation, participants will be engaged in a mental training task (sequential finger tapping-task).",[15],[31],{"name":32,"affiliation":33,"role":34},"Marine MONDINO, PhD","CH le Vinatier","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":40,"email":41},"Lydie SARTELET","CONTACT","0 437915531","+33","lydie.sartelet@ch-le-vinatier.fr",[43],{"facility":44,"status":45,"city":46,"state":25,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Centre Hospitalier le Vinatier","RECRUITING","Bron","69678","France","FR",{"type":51,"coordinates":52},"Point",[53,54],4.91303,45.73865,{"lat":54,"lon":53},[57,61,65,66,69],{"name":58,"role":38,"phone":59,"phoneExt":40,"email":60},"Marine Mondino","0437915565","marine.mondino@ch-le-vinatier.fr",{"name":62,"role":38,"phone":63,"phoneExt":40,"email":64},"Jérôme Brunelin","0437915297","jerome.brunelin@ch-le-vinatier.fr",{"name":58,"role":34,"phone":25,"phoneExt":25,"email":25},{"name":67,"role":68,"phone":25,"phoneExt":25,"email":25},"Frédéric Haesebaert","SUB_INVESTIGATOR",{"name":70,"role":68,"phone":25,"phoneExt":25,"email":25},"Jerome Brunelin",{"type":72,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100526914","motor-imagery-in-aphantasia-100526914",false,"NCT06140940","Motor Imagery in Aphantasia","Probing and Modulating Motor Imagery Capacities in Aphantasia","OLIPHANT","Inclusion Criteria:\n\n* For the aphantasia group only: congenital aphantasia defined as a life-long inability to generate mental imagery (confirmed by a total score of 32 or less on the VVIQ, which is the gold standard questionnaire for aphantasia)\n* For the no-aphantasia group only: typical mental imagery capacities (confirmed by a total score of more than 32 on the VVIQ)\n* Covered by public health insurance\n* Understanding the French language\n* Signed written informed consent after being informed about the study\n\nExclusion Criteria:\n\n* Presence or history of a somatic, neurologic, or mental illness\n* Actual pain or musculoskeletal disorders at the upper limb\n* Having a regular musical activity (more than once a week) because of high manual dexterity\n* Contraindication for noninvasive brain stimulation including the presence of ferromagnetic or magnetic sensitive metal objects implanted in the head or in close proximity (e.g., brain stent, clip, cochlear implants, or stimulator)\n* Pregnancy (controlled by urine pregnancy test in females without reported contraception)\n* Active seizure disorder or history of seizures\n* Participants under curatorship\u002Fguardianship",true,"ALL","18 Years",{"count":85,"type":86},40,"ESTIMATED","INTERVENTIONAL",[89],"NA","The present study aims to characterize and modulate motor imagery abilities in individuals with aphantasia. The investigators will characterize the neurophysiological and physiological underpinnings of mental imagery abilities in participants with aphantasia by investigating several indices of motor imagery abilities and comparing them to participants with typical mental imagery abilities. The investigators will investigate whether non-invasive brain stimulation applied to the primary motor cortex improves mental imagery abilities in participants with aphantasia.",[92],"Aphasia","2025-07-23",{"date":95,"type":96},"2025-07-24","ACTUAL",{"date":98,"type":96},"2024-03-28",{"date":100,"type":86},"2028-01-01",{"name":5,"class":6},1]