[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586785":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":55,"collaborators":58,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":26,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Georgia State University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Training Group","EXPERIMENTAL","During the acquisition session, this group will undergo perturbation training on the treadmill while wearing a safety harness. Then, they will experience an unexpected slip and trip while wearing a safety harness and walking overground. During the 3-month and 6-month retention sessions, they will experience a slip and trip during treadmill walking and a slip and trip during overground walking.",[13],"Behavioral: Perturbation Training",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","ACTIVE_COMPARATOR","During the acquisition session, this group will walk on the treadmill without perturbations for the same amount of time as the training group. Then, they will experience an unexpected slip and trip while wearing a safety harness and walking overground. During the 3-month and 6-month retention sessions, they will experience a slip and trip during treadmill walking and a slip and trip during overground walking.",[19],"Behavioral: Treadmill Walking",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Perturbation Training","Unexpected slips blended with trips and unperturbed walking trials on a treadmill. A safety harness will be worn at all times.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Treadmill Walking","Treadmill walking for the same amount of time as the training group without perturbation. A safety harness will be worn at all times.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Feng Yang, Ph.D.","CONTACT","404-413-8357","fyang@gsu.edu",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Georgia State University Biomechanics Lab","RECRUITING","Atlanta","Georgia","30303","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-84.38798,33.749,{"lat":50,"lon":49},[53],{"name":54,"role":34,"phone":35,"phoneExt":26,"email":36},"Feng Yang, PhD",{"type":56,"investigatorFullName":54,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Professor",[59],{"name":60,"class":6},"National Multiple Sclerosis Society","100586785","motor-learning-of-fall-resistant-skills-through-slip-and-trip-exposure-in-multiple-sclerosis-100586785",false,"NCT06919900","Motor Learning of Fall Resistant Skills Through Slip and Trip Exposure in Multiple Sclerosis","STRES-MS","Inclusion Criteria:\n\n1. Clinically confirmed multiple sclerosis\n2. At least 45 years old\n3. Able to walk independently at least 25 feet\n4. Able to stand independently for at least 30 seconds\n5. Patient Determined Disability Steps score between 0 and 4\n6. Free from pregnancy\n7. Montreal Cognitive Assessment score of 23 or higher\n\nExclusion Criteria:\n\n1. Previous experience with perturbation training\n2. T-score from the dual x-ray absorptiometry (DXA) scan of less than -2.5\n3. Coexisting psychiatric disorders or other neurological conditions, severe medical illness, or cardiovascular diseases\n4. Participants have had a relapse in the past 8 weeks","ALL","45 Years","89 Years",{"count":72,"type":73},64,"ESTIMATED","INTERVENTIONAL",[76],"NA","The primary purpose of this interventional study is to examine the overall motor learning capacity from exposure to repeated perturbations among ambulatory people with multiple sclerosis (MS). This project will advance our understanding of learning new motor skills from exposure to external perturbations. If it is proven that people with MS can learn motor skills from perturbation training, the findings from this study will pave a theoretical foundation for applying perturbation training as a promising fall prevention intervention for people with MS.",[79],"Multiple Sclerosis (Relapsing Remitting)",[81,82,83,84],"Falls","Fall prevention","Slips","Trips","2026-06-15",{"date":87,"type":88},"2026-06-17","ACTUAL",{"date":90,"type":88},"2026-04-06",{"date":92,"type":73},"2028-12",{"name":5,"class":6},1]