[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612359":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":31,"responsibleParty":43,"collaborators":18,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":47,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":18,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":69,"overallStatus":76,"whyStopped":18,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Chung Shan Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Cold Water Rinse","EXPERIMENTAL","Participants will rinse their mouth with cold water at approximately 15-20°C, four times daily for 30-60 seconds throughout six weeks of radiotherapy, followed by a two-week follow-up period.",[13],"Behavioral: Water Rinse at Different Temperatures",{"label":15,"type":16,"description":17,"interventionNames":18},"Room Temperature Water Rinse","NO_INTERVENTION","Participants will rinse their mouth with room-temperature water at approximately 30-35°C, with identical frequency and duration as the experimental arm.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","Water Rinse at Different Temperatures","rinse their mouth with cold water at approximately 15-20°C",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Yueh-Chun Lee, MD-PhD","CONTACT","+886937355888","lee.yuehchun@gmail.com",[32],{"facility":5,"status":18,"city":33,"state":34,"zip":18,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":18},"Taichung","Taiwan (r.o.c.)","Taiwan","TW",{"type":38,"coordinates":39},"Point",[40,41],120.6839,24.1469,{"lat":41,"lon":40},{"type":44,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100612359","mouthwash-temperature-and-oral-mucositis-in-head-and-neck-radiotherapy-100612359",false,"NCT07252557","Mouthwash Temperature and Oral Mucositis in Head and Neck Radiotherapy","Effectiveness of Different Mouthwash Temperatures on Oral Mucositis Pain and Patient Comfort During Radiotherapy for Head and Neck Cancer: A Randomized Controlled Trial","CoolRinseHNC","Inclusion Criteria:\n\n* Histologically confirmed head and neck cancer (HNC) receiving radiotherapy for the first time, with or without concurrent chemotherapy.\n* Conscious, communicative, and able to perform the rinsing procedure and complete questionnaires.\n* Provided written informed consent prior to enrollment.\n\nExclusion Criteria:\n\n* Non-HNC diagnoses or radiotherapy to sites outside the oral\u002Foropharyngeal region.\n* Cognitive impairment or inability to complete the rinsing protocol.","ALL","20 Years","80 Years",{"count":57,"type":58},200,"ESTIMATED","INTERVENTIONAL",[61],"NA","This single-center randomized controlled trial evaluates the effects of cold (15-20°C) versus room-temperature (30-35°C) water gargling on oral mucositis severity, pain, and comfort in patients with head and neck cancer undergoing radiotherapy. Participants will rinse their mouth four times daily for 30-60 seconds over a 6-week radiotherapy course, with follow-up for two additional weeks. The study hypothesizes that cold-water rinsing can reduce the severity of radiation-induced oral mucositis (RTOM) and pain, improve oral comfort, and minimize treatment interruptions.",[64,65,66,67,68],"Head and Neck Cancer (H&Amp;Amp;N)","Radiation-induced Oral Mucositis","Supportive Care","Nursing Interventions","Radiotherapy Side Effects",[70,71,72,9,66,73,74,75],"Head and Neck Cancer","Radiation-Induced Oral Mucositis","Water Temperature","Pain Management","Radiotherapy","Nursing Intervention","NOT_YET_RECRUITING","2025-11-24",{"date":79,"type":80},"2025-11-26","ACTUAL",{"date":82,"type":58},"2026-01-01",{"date":84,"type":58},"2027-03-31",{"name":5,"class":6},1]