[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100053577":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":32,"centralContacts":36,"locations":42,"responsibleParty":59,"collaborators":40,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":40,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":85,"overallStatus":45,"whyStopped":40,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Emory University","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Older adults with MCI","EXPERIMENTAL","Participants will attend daily (3-5 times\u002Fweek) lessons that will last 1.5h for a month (e.g., 3-5 weeks) and will receive contact and monitoring from study staff. The Principal Investigator will monitor fidelity via weekly reports from interventionists.",[13],"Other: Complex Rhythmic Movement Sequences (CRMS) Sessions",{"label":15,"type":16,"description":11,"interventionNames":17},"Older adults without MCI","ACTIVE_COMPARATOR",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Older adults with PD","Participants will attend daily (3-5 times\u002Fweek) lessons that will last 1.5 h for a month (e.g., 3-5 weeks) and will receive contact and monitoring from study staff. The Principal Investigator will monitor fidelity via weekly reports from interventionists.",[13],{"label":23,"type":16,"description":11,"interventionNames":24},"Young adults and adults with normal cognition (NC)",[13],[26],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"Complex Rhythmic Movement Sequences (CRMS) Sessions","Researchers will establish complex rhythmic movement sequences (CRMS) as an experimental paradigm to identify spatial and temporal components and learning time courses of complex rhythmic movement.\n\nParticipants will dance with new partners every 15-20 minutes, a widely practiced method of the dance community to enhance learning. The class format is:\n\n1. practicing previously learned steps\n2. 25-minute warmup, partnering\u002Frhythmic exercises\n3. learning new steps\n4. combining old and new steps\n5. cool down\n\nParticipants dance both leading and following roles, learn how to interpret motor goals through touch, and perform activities to foster understanding of the temporal relationship of movement to music.",[9,19,15,23],[31],"Spatiotemporal activity modification (STEAM)",[33],{"name":34,"affiliation":5,"role":35},"Madeleine E. Hackney, PhD","PRINCIPAL_INVESTIGATOR",[37],{"name":34,"role":38,"phone":39,"phoneExt":40,"email":41},"CONTACT","314-412-4852",null,"mehackn@emory.edu",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Emory University, Executive Park, Wesley Woods","RECRUITING","Atlanta","Georgia","30329","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-84.38798,33.749,{"lat":55,"lon":54},[58],{"name":34,"role":38,"phone":40,"phoneExt":40,"email":41},{"type":35,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":40,"oldOrganization":40},"Madeleine Eve Hackney","Associate Professor, Emory University School of Medicine","100053577","moving-yourself-in-space-and-time-mystic-100053577",false,"NCT07697664","Moving Yourself in Space and Time: MYSTIC","Moving Yourself in Space and Time Identifying Spatial and Temporal Components of Complex Rhythmic Movement Training for People With Parkinson's Disease and Cognitive Impairment","MYSTIC","Inclusion Criteria for Young adults and adults with normal cognition (NC):\n\n* 18 to 35 Years old\n* Montreal Cognitive Assessment (MoCA) score of 26 to 30\n\nInclusion Criteria for Older Adults:\n\n* 50 to 79 with or without MCI\n* 50 to 79 years old with Parkinson's disease (PD), who do NOT have impaired decision-making capacity\n* Participants who achieve less than 150 minutes moderate or 75 minutes vigorous aerobic activity per week (as per the US Department of Health and Human Services (HHS)),\n\nExclusion Criteria for all groups:\n\n* Acute medical illness requiring hospitalization;\n* Uncontrolled congestive heart failure;\n* History of stroke in the past three years;\n* Inability to perform study procedures;\n* Medical or physical conditions that would preclude participation (e.g., severe arthritis or mobility problems, uncontrolled hypertension or diabetes, renal failure, history of angina with activity);\n* On medications that could adversely affect cognition, e.g., antipsychotics, opioids, stimulants, chemotherapy, and neurologic prescriptions to treat Multiple Sclerosis. When applicable, enrollment will be delayed until dosages are stable on e.g., Aricept, Namenda, anticholinesterase inhibitors, for at least 3 months\n* Psychotic disorders\n* Confounding neurologic conditions \\[e.g., active central nervous system (CNS) opportunistic infections, seizure disorders, head injury with loss of consciousness \\>30 minutes, intracranial neoplasms, stroke with neurological or neuropsychiatric sequelae\\]\n* Substance Use Disorder, Major Depressive Disorder, and Generalized Anxiety Disorder within six months of evaluation.\n* Inability to provide informed consent",true,"ALL","18 Years","79 Years",{"count":75,"type":76},210,"ESTIMATED","INTERVENTIONAL",[79],"NA","This study is being done to answer the question: Do people with Parkinson's benefit from a new stepping therapy, and how do people with Parkinson's best learn new steps and rhythms set to music? Researchers will also compare individuals with Parkinson's Disease with people with Mild Cognitive Impairment, and with people with neither of these conditions.\n\nThe purpose of this study is to identify principles of human-music interactions to establish underlying guiding theories for application to music-based rehabilitation for older populations with neurodegenerative disease, leading to more refined and targeted music-based rhythmic movement therapies.",[82,83,84],"Parkinson's Disease (PD)","Alzheimer's Disease (AD) and Related Disorders","Older Adults (60 - 85 Years Old)",[86,87,88,89,90,91,92,93,94],"Dance","Music","Therapy","Rehabilitation","Neurodegenerative","Parkinson's","Alzheimer's","Motor learning","Motor control","2026-07-07",{"date":97,"type":98},"2026-07-13","ACTUAL",{"date":100,"type":98},"2022-03-25",{"date":102,"type":76},"2028-12",{"name":5,"class":6},1]