[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100531366":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":10,"centralContacts":23,"locations":29,"responsibleParty":50,"collaborators":10,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":10,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":10,"enrollmentInfo":63,"targetDuration":66,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Jiangsu Cancer Institute & Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Operable group",null,"Early-stage patients with radical surgery or operable patients with neoadjuvant treatment",[13],"Procedure: Operable",{"label":15,"type":10,"description":16,"interventionNames":10},"Inoperable group","Advanced-stage patients receive non-surgery therapies.",[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"PROCEDURE","Operable","Enrolled patients capable of surgical treatment",[9],[24],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Rong Yin, M.D., Ph.D.","CONTACT","18305185629","rong_yin@njmu.edu.cn",[30],{"facility":5,"status":31,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","Nanjing","Jiangsu","210009","China","CN",{"type":38,"coordinates":39},"Point",[40,41],118.77778,32.06167,{"lat":41,"lon":40},[44,47],{"name":45,"role":26,"phone":10,"phoneExt":10,"email":46},"Jifeng Feng, M.D., Ph.D.","fjif@vip.sina.com",{"name":48,"role":26,"phone":10,"phoneExt":10,"email":49},"Siwei Wang, M.D., Ph.D.","wangsiwei@njmu.edu.cn",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Rong Yin, MD PhD","Professor","100531366","mrd-guided-prognosis-prediction-and-adjuvant-treatment-based-on-ctc-and-ctdna-in-nsclc-100531366",false,"NCT06198868","MRD-guided Prognosis Prediction and Adjuvant Treatment Based on CTC and ctDNA in NSCLC","Minimal Residual Disease (MRD) Guided Prognosis Prediction and Adjuvant Treatment Based on Expression and Mutational Signatures of Circulating Tumor Cell (CTC) and Circulating Tumor DNA (ctDNA) in Non-small Cell Lung Cancer","Inclusion Criteria:\n\n1. Written informed consent must be signed before implementing any enrollment-related procedures;\n2. Age ≥18 years old;\n3. Patients with histologically or cytologically confirmed stage IIA-IIIC NSCLC (International Association for the Study of Lung Cancer and American Joint Committee on Classification of Cancer, 8th Edition TNM staging)；\n4. There is no special restriction on the source of genetic test report.\n5. According to the Response Evaluation Criteria in Solid Tumors (RECIST, version 1.1), there is at least one radiographically measurable lesion.\n6. Have not received any previous systemic antitumor therapy for advanced diseases.\n7. No serious abnormalities of hematopoietic function, heart, lung, liver, kidney function and immune system.\n8. ECOG score: 0-1;\n9. Expected survival time \\> 3 months.\n\nExclusion Criteria:\n\n1. Received surgical treatment for lung tumors.\n2. Received neoadjuvant chemotherapy or radiotherapy.\n3. Received cellular therapy within the last 1 year.\n4. Treated but uncontrolled diabetes, mellitus, asthma, autoimmune diseases and other chronic diseases.\n5. Participated in other clinical trials (including research vaccines, drugs, medical devices, etc.) within one month.","ALL","18 Years",{"count":64,"type":65},60,"ESTIMATED","5 Years","OBSERVATIONAL","This is a prospective cohort study, which aims to evaluate the effectiveness and superiority of a novel minimal residual disease-guided prognosis monitoring and adjuvant treatment in stage IIA-IIIC non-small cell lung cancer.",[70],"Non-small Cell Lung Cancer",[72,73,74,75],"NSCLC","Minimal Residual Disease","Prognosis monitoring","Adjuvant treatment","2024-01-10",{"date":78,"type":79},"2024-01-12","ACTUAL",{"date":81,"type":65},"2024-02-01",{"date":83,"type":65},"2027-02-01",{"name":5,"class":6},1]