[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100532099":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":26,"locations":31,"responsibleParty":50,"collaborators":10,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":10,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Shengjing Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental: Diagnostic (MRE)",null,"Patients undergo a preoperative routine MRI scan and MRE the day before their scheduled surgery to assess OSS and NOSS. After surgery, the HGP of tumor will be assessed by H\\&E-stained sections.",[13],"Diagnostic Test: Magnetic Resonance Elastography and routine MRI",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","Magnetic Resonance Elastography and routine MRI","Assessed boundary conditions through MRE-base SII before surgery and recorded HGP of tumor after surgery.",[9],[21],"MRE",[23],{"name":24,"affiliation":5,"role":25},"Yu Shi, M.D.","PRINCIPAL_INVESTIGATOR",[27],{"name":24,"role":28,"phone":29,"phoneExt":10,"email":30},"CONTACT","18940259980","18940259980@163.com",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Shengjing Hospital of China Medical University","RECRUITING","Shenyang","Liaoning","110004","China","CN",{"type":41,"coordinates":42},"Point",[43,44],123.43278,41.79222,{"lat":44,"lon":43},[47],{"name":48,"role":28,"phone":49,"phoneExt":10,"email":30},"Yu Shi, MD","+8618940259980",{"type":25,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Yu Shi","Deputy director of department of radiology","100532099","mre-for-assessment-of-histopathological-growth-patterns-in-colorectal-liver-metastases-100532099",false,"NCT06208397","MRE for Assessment of Histopathological Growth Patterns in Colorectal Liver Metastases","Noninvasive Evaluation in Diagnosis and Treatment of Histopathological Growth Patterns in Colorectal Liver Metastases Using MR Elastography-based Shear Strain Mapping","Inclusion Criteria:\n\n* Diagnosed CRLM\n* Pathologic results obtained in surgical patients\n* No contraindications for magnetic resonance imaging examination\n\nExclusion Criteria:\n\n* Image quality does not meet the measurement requirements.\n* the diameter of CRLM \\\u003C1cm\n* Combined with other important organ dysfunction\n* Combined with malignant tumor\n* Patients who do not sign an informed consent\n* Patients with metallic implants or foreign bodies in their bodies (pacemakers, artificial metallic heart valves, metal joints, metal implants, and those who cannot remove dentures, insulin pumps, or contraceptive rings)",true,"ALL","18 Years","80 Years",{"count":65,"type":66},50,"ESTIMATED","OBSERVATIONAL","The goal of this study is to investigate the value of MR elastography-based SII as a means of detecting HGP noninvasively in patients with pathology-proven CRLM. MRE will provide a direct measure of tumor-liver adhesion to investigate the relationship between imaging findings and pathophysiological changes in the Liver.",[70],"Metastatic Colorectal Cancer",[72,73,74,75],"colorectal cancer liver metastasis","Magnetic Resonance Imaging","Magnetic Resonance Elastography","Histopathological growth patterns","2025-05-14",{"date":78,"type":79},"2025-05-15","ACTUAL",{"date":81,"type":79},"2023-12-24",{"date":83,"type":66},"2026-12-24",{"name":5,"class":6},1]