[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100571489":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":35,"responsibleParty":53,"collaborators":11,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":59,"sex":65,"minAge":11,"maxAge":11,"enrollmentInfo":66,"targetDuration":11,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":37,"whyStopped":11,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Beijing Tiantan Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Open Surgery (anterior temporal lobectomy, ATL)","EXPERIMENTAL",null,[13],"Procedure: Open Surgery",{"label":15,"type":16,"description":11,"interventionNames":17},"Minimally Invasive Surgery (MRgLITT)","ACTIVE_COMPARATOR",[18],"Procedure: Resonance-guided Laser Interstitial Thermal Therapy (MRgLITT)",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"PROCEDURE","Resonance-guided Laser Interstitial Thermal Therapy (MRgLITT)","MRgLITT employs laser energy delivered through a stereotactically placed laser applicator to precisely ablate the epileptogenic tissue.",[15],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Open Surgery","Traditional Open Surgery",[9],[30],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"Kai Zhang, Dr.","CONTACT","86 01059975051","zhangkai62035@sina.com",[36],{"facility":5,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"RECRUITING","Beijing","Beijing Municipality","100070","China","CN",{"type":44,"coordinates":45},"Point",[46,47],116.39723,39.9075,{"lat":47,"lon":46},[50],{"name":51,"role":32,"phone":33,"phoneExt":11,"email":52},"Jiajie Mo, Dr.","jiajiemo@foxmail.com",{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Kai Zhang","Dr.","100571489","mrglitt-for-mtle-a-probe-trial-100571489",false,"NCT06720922","MRgLITT for mTLE: A PROBE Trial","Magnetic Resonance-guided Laser Interstitial Thermal Therapy for Mesial Temporal Lobe Epilepsy: A Prospective, Randomized, Open Blinded, End-point Trial","MINE","Inclusion Criteria:\n\n* 18-65 years.\n* Drug-resistant mesial temporal lobe epilepsy.\n* Seizure frequency ≥ 1 time \u002Fmonth.\n* Participants approved.\n\nExclusion Criteria:\n\n* History of brain surgery.\n* Intracranial space occupying lesions.\n* Individuals with significant medical comorbidities or conditions that pose an excessive risk for surgery, such as severe cardiovascular disease, respiratory disorders, or uncontrolled systemic infections.","ALL",{"count":67,"type":68},120,"ESTIMATED","INTERVENTIONAL",[71],"NA","How does magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) impact clinical prognosis in mesial temporal lobe epilepsy (mTLE)?",[74],"Temporal Lobe Epilepsy (TLE)",[76,26,77],"Magnetic Resonance-guided Laser Interstitial Thermal Therapy","Temporal Lobe Epilepsy","2026-01-19",{"date":80,"type":81},"2026-01-21","ACTUAL",{"date":83,"type":81},"2025-07-21",{"date":85,"type":68},"2028-01-01",{"name":5,"class":6},1]