[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100528632":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":24,"locations":30,"responsibleParty":48,"collaborators":10,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":10,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":10,"overallStatus":33,"whyStopped":10,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"Universidade Nova de Lisboa","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control",null,"Healthy volunteers",[13],"Diagnostic Test: MRI advanced techniques",{"label":15,"type":10,"description":16,"interventionNames":17},"Disease","Patients affected by disease",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DIAGNOSTIC_TEST","MRI advanced techniques","Participants will be submitted to MRI studies at diagnosis, during disease evolution and after treatment. Data collected will be analysed by two different neuroradiologists using advanced techniques.",[9,15],[25],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Nuno A.R. Cristino, M.D.","CONTACT","+351919484946","nuno.cristino.ext@nms.unl.pt",[31],{"facility":32,"status":33,"city":34,"state":10,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Hospital da Luz Setúbal","RECRUITING","Setúbal","2900-722","Portugal","PT",{"type":39,"coordinates":40},"Point",[41,42],-8.8882,38.5244,{"lat":42,"lon":41},[45],{"name":46,"role":27,"phone":28,"phoneExt":10,"email":47},"Nuno Cristino, MD","nuno.remedio.cristino@hospitaldaluz.pt",{"type":49,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100528632","mri-analysis-and-degenerative-spine-100528632",false,"NCT06163300","MRI Analysis and Degenerative Spine","Inclusion Criteria:\n\n* Age between 50 and 85 years\n* Diagnosis of spinal disease by clinical and imagiological criteria\n* More than 3 months duration of disease\n* Ability to give consent\n* Fluent portuguese speaker\n\nExclusion Criteria:\n\n* Previous spine surgery\n* Spinal instability\n* Neurological disease that might interfere with walking\n* Known orthopedic conditions that causes significant gait impairment\n* Dementia or development disorder with cognitive impairment\n* Inability to give consent",true,"ALL","50 Years","85 Years",{"count":61,"type":62},200,"ESTIMATED","OBSERVATIONAL","Analysis of MRI advanced techniques in degenerative spinal disease.\n\nThe main questions it aims to answer are:\n\n* Can we assess microstructural integrity of compressed nerve roots in degenerative spinal disease\n* What are the image biomarkers affected by disease\n* How they evolve with disease progression and treatment",[66],"Spine Disease","2024-01-26",{"date":69,"type":70},"2024-01-30","ACTUAL",{"date":72,"type":70},"2024-01-01",{"date":74,"type":62},"2026-09",{"name":5,"class":6},1]