[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100596051":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":26,"centralContacts":21,"locations":31,"responsibleParty":43,"collaborators":21,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":48,"sex":54,"minAge":55,"maxAge":21,"enrollmentInfo":56,"targetDuration":21,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":76,"whyStopped":21,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Campus Bio-Medico University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"PENG Block with MRI-Based Local Anesthetic Spread Assessment","EXPERIMENTAL","All patients receive standardized multimodal analgesia before surgery. Patients in this arm receive an ultrasound-guided PENG block in the supine position under sterile conditions. A low-frequency (2-5 MHz) curvilinear probe is placed above the AIIS and rotated \\~45° to align with the pubic ramus. Using an in-plane lateral-to-medial approach, a 10 cm, 20G needle is advanced to the interfascial plane between the iliopsoas tendon and pubic ramus. After negative aspiration, ropivacaine hydrochloride 0.5% is injected in 5 mL increments up to 20 mL, observing spread via ultrasound. A pelvic MRI is then performed to assess anesthetic diffusion before the patient proceeds to total hip arthroplasty.",[13,14],"Procedure: PENG Block","Procedure: Magnetic resonance imaging",[16,22],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"PROCEDURE","PENG Block","Preoperative ultrasound giuded PENG block (ropivacaine 0,5% 20mL)",[9],null,{"type":17,"name":23,"description":24,"armGroupLabels":25,"otherNames":21},"Magnetic resonance imaging","The patient will undergo a pelvic MRI to assess anesthetic diffusion after PENG block",[9],[27],{"name":28,"affiliation":29,"role":30},"Francesca Gargano, Medical Doctor","Policlinico Universitario Campus Bio-Medico","PRINCIPAL_INVESTIGATOR",[32],{"facility":29,"status":21,"city":33,"state":34,"zip":35,"country":34,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":21},"Roma","Italy","00128","IT",{"type":38,"coordinates":39},"Point",[40,41],11.10642,44.99364,{"lat":41,"lon":40},{"type":30,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":21,"oldOrganization":21},"Francesca Gargano","Medical doctor, Anesthesiologist","100596051","mri-based-assessment-of-local-anesthetic-spread-in-the-peng-block-compartment-100596051",false,"NCT07040423","MRI-Based Assessment of Local Anesthetic Spread in the PENG Block Compartment","Evaluation of Local Anesthetic Distribution in the PENG Block Compartment Using Pelvic MRI","MRI-PENG","Inclusion Criteria:\n\n* Patients scheduled for total hip replacement surgery\n* Age ≥ 18 years\n* ASA physical status classification I-III\n* Signed informed consent obtained\n* Orthopedic indication for preoperative MRI study\n\nExclusion Criteria:\n\n* Allergy to local anesthetics\n* Infection at the planned puncture site\n* Refusal or inability to provide informed consent\n* Age \\\u003C 18 years\n* Claustrophobia\n* Altered consciousness or severe dementia\n* Presence of MRI-incompatible implanted devices (e.g., pacemakers implanted before 2000)\n* Pregnancy or breastfeeding","ALL","18 Years",{"count":57,"type":58},6,"ESTIMATED","INTERVENTIONAL",[61],"NA","This study uses MRI imaging to evaluate the spread of local anesthetic following the administration of a pericapsular nerve group (PENG) block. The goal is to determine whether a distinct fascial plane exists between neurovascular structures, potentially explaining the block's observed clinical effectiveness.",[64,65],"Total Hip Arthroplasty (THA)","Postoperative Pain Management After Total Hip Arthroplasty",[67,68,69,70,71,72,73,74,75],"Anesthetics","Anesthetics, Local","Pain","Acute Pain","PENG block","Pelvic MRI","Regional anesthesia","Fascial plane","Local anesthetic spread","NOT_YET_RECRUITING","2025-06-18",{"date":79,"type":80},"2025-06-27","ACTUAL",{"date":82,"type":58},"2025-06",{"date":84,"type":58},"2026-10",{"name":5,"class":6},1]