[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100486024":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":31,"centralContacts":35,"locations":43,"responsibleParty":80,"collaborators":30,"id":82,"slug":83,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":86,"acronym":30,"eligibilityCriteria":87,"healthyVolunteers":84,"sex":88,"minAge":89,"maxAge":30,"enrollmentInfo":90,"targetDuration":30,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":30,"overallStatus":45,"whyStopped":30,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"University of Chicago","OTHER",[8,13,17,21],{"label":9,"type":6,"description":10,"interventionNames":11},"High Risk- Positive Germline Mutation (n=40):","Men who harbor known germline mutations that have been associated with an increased risk of prostate cancer and aggressive disease (e.g. BRCA2, ATM, PALB2, etc.) with or without a known family history of prostate cancer.",[12],"Other: Prostate MRI",{"label":14,"type":6,"description":15,"interventionNames":16},"High Risk- High GRS (n=40):","Men who harbor significantly increased disease risk based upon genetic risk score (GRS) value \\>1.5 with or without a known family history of prostate cancer.",[12],{"label":18,"type":6,"description":19,"interventionNames":20},"High Risk- Family History (n=45):","Men with a family history of prostate cancer in at least one sibling, father, uncle, or grandfather but no known increased genetic risk of prostate cancer (has no pathogenic or likely pathogenic mutation along with a low genetic risk score (GRS\\\u003C1.5).",[12],{"label":22,"type":6,"description":23,"interventionNames":24},"Low Risk (n=125):","No known germline mutation, low genetic risk score (GRS \\\u003C1.5), and no known family history of prostate cancer.",[12],[26],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"Prostate MRI","Group placement is determined by GRS score, Family history, and germline testing",[18,14,9,22],null,[32],{"name":33,"affiliation":5,"role":34},"Scott Eggener, MD","PRINCIPAL_INVESTIGATOR",[36,40],{"name":33,"role":37,"phone":38,"phoneExt":30,"email":39},"CONTACT","7737021001","seggener@surgery.bsd.uchicago.edu",{"name":41,"role":37,"phone":30,"phoneExt":30,"email":42},"Teresa Barry","tbarry@bsd.uchicago.edu",[44,62],{"facility":5,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","Chicago","Illinois","60637","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-87.65005,41.85003,{"lat":55,"lon":54},[58,60],{"name":33,"role":37,"phone":59,"phoneExt":30,"email":39},"773-702-1001",{"name":41,"role":37,"phone":61,"phoneExt":30,"email":42},"7737025681",{"facility":63,"status":45,"city":64,"state":47,"zip":65,"country":49,"countryCode":50,"cosmosGeoPoint":66,"geoPoint":70,"contacts":71},"NorthShore University Health System - Glenbrook Hospital","Glenview","60026",{"type":52,"coordinates":67},[68,69],-87.78784,42.06975,{"lat":69,"lon":68},[72,75,78],{"name":73,"role":37,"phone":30,"phoneExt":30,"email":74},"Pooja Talaty","ptalaty@northshore.org",{"name":76,"role":37,"phone":30,"phoneExt":30,"email":77},"Svetlana Brumer","sbrumer@northshore.org",{"name":79,"role":34,"phone":30,"phoneExt":30,"email":30},"Brian Helfand, MD",{"type":81,"investigatorFullName":30,"investigatorTitle":30,"investigatorAffiliation":30,"oldNameTitle":30,"oldOrganization":30},"SPONSOR","100486024","mri-screening-in-men-at-high-risk-of-developing-prostate-cancer-100486024",false,"NCT05608694","MRI Screening in Men at High Risk of Developing Prostate Cancer","Inclusion Criteria:\n\n* Male age 18 and older\n* No known history of prostate cancer\n* No previous prostate resection or ablation (e.g. TURP, photovaporization)\n\nExclusion Criteria:\n\n* Unable to tolerate MRI due to metal fragments or claustrophobia\n* Lack of a rectum\n* Hip arthroplasty","MALE","18 Years",{"count":91,"type":92},250,"ESTIMATED","INTERVENTIONAL",[95],"NA","The purpose of this study is to determine whether or not Magnetic Resonance Images (MRI) will identify high-grade cancers earlier and more frequently in men at high risk of developing prostate cancer.",[98],"Prostate Cancer Screening","2026-02-27",{"date":101,"type":102},"2026-03-02","ACTUAL",{"date":104,"type":102},"2022-03-02",{"date":106,"type":92},"2039-03-01",{"name":5,"class":6},2]