[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100490227":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":14,"responsibleParty":31,"collaborators":35,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":7,"eligibilityCriteria":45,"healthyVolunteers":41,"sex":46,"minAge":47,"maxAge":7,"enrollmentInfo":48,"targetDuration":7,"studyType":51,"phases":7,"briefSummary":52,"conditions":53,"keywords":7,"overallStatus":17,"whyStopped":7,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":64},{"fullName":5,"class":6},"Erasmus Medical Center","OTHER",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Justin Pijpe, MD DDS PhD MSc","CONTACT","+31641397764","j.pijpe@erasmusmc.nl",[15],{"facility":16,"status":17,"city":18,"state":7,"zip":19,"country":20,"countryCode":21,"cosmosGeoPoint":22,"geoPoint":27,"contacts":28},"Erasmus Mc","RECRUITING","Rotterdam","3015gd","Netherlands","NL",{"type":23,"coordinates":24},"Point",[25,26],4.47917,51.9225,{"lat":26,"lon":25},[29],{"name":30,"role":11,"phone":12,"phoneExt":7,"email":13},"justin pijpe, md dds phd",{"type":32,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Dr. Justin Pijpe","Assistent Professor",[36],{"name":37,"class":38},"Institut Straumann AG","INDUSTRY","100490227","mucograft-seal-in-arp-follow-up-100490227",false,"NCT05663385","Mucograft Seal in ARP Follow-up","Alveolar Ridge Preservation With a Xenograft (Bio-Oss® Collagen) and a Collagen Matrix (Mucograft® Seal) or a Free Connective Tissue Graft Versus Spontaneous Healing:A 5-year Follow up","Inclusion Criteria:\n\n* All patients previously included in the above mentioned RCT.\n\nExclusion Criteria:\n\n* Patients treated with radiotherapy during follow-up in the head-and-neck region or current chemotherapy; disability (mental and\u002For physical) to maintain basic oral hygiene procedures.","ALL","18 Years",{"count":49,"type":50},75,"ESTIMATED","OBSERVATIONAL","Rationale: Early implant placement with alveolar ridge preservation (ARP) using either a collagen matrix or a palatal graft rendered similar esthetic, clinical and PROMs to early implant placement without ARP, up to 1 year after functional loading.\n\nObjective: The aim of this study is to evaluate esthetic and clinical outcomes and patient satisfaction following single-tooth replacement in the anterior maxilla in patients treated with a xenograft and a collagen matrix or a free connective tissue graft versus spontaneous healing 5 years after loading\n\nStudy design: prospective observational study with 5-year follow-up\n\nIntervention (if applicable): not applicable\n\nMain study parameters\u002Fendpoints: Comparison of the level of the buccal marginal gingiva (midfacial mucosa level) between ARP versus spontaneous healing\n\nSecondary parameters\u002Fendpoint: Peri-implant esthetic score (PES) and white esthetic score (WES), complications, implant survival; and success, Plaque Index, Modified bleeding index, Gingival Index, Probing Depth, PROMs, bone and soft tissue volumetric dimensional changes.",[54],"Dental Implant","2025-08-07",{"date":57,"type":58},"2025-08-12","ACTUAL",{"date":60,"type":58},"2024-04-16",{"date":62,"type":50},"2025-10-01",{"name":5,"class":6},1]