[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100321802":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":32,"locations":42,"responsibleParty":251,"collaborators":254,"id":259,"slug":260,"hasResults":261,"nctId":262,"briefTitle":263,"officialTitle":264,"acronym":265,"eligibilityCriteria":266,"healthyVolunteers":261,"sex":267,"minAge":18,"maxAge":268,"enrollmentInfo":269,"targetDuration":18,"studyType":272,"phases":273,"briefSummary":275,"conditions":276,"keywords":278,"overallStatus":45,"whyStopped":18,"lastUpdateSubmitDate":291,"lastUpdatePostDateStruct":292,"startDateStruct":295,"completionDateStruct":297,"leadSponsor":299,"locationsCount":300},{"fullName":5,"class":6},"University of Leipzig","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Perioperative mucous fistula refeeding","EXPERIMENTAL","Perioperative mucous fistula refeeding between enterostomy creation and enterostomy closure",[13],"Other: mucous fistula refeeding",{"label":15,"type":16,"description":17,"interventionNames":18},"No mucous fistula refeeding","NO_INTERVENTION","No perioperative mucous fistula refeeding",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"mucous fistula refeeding","Transfer of infants' own stool",[9],[25,29],{"name":26,"affiliation":27,"role":28},"Omid Madadi-Sanjani, PD Dr. med.","University Medical Center Hamburg-Eppendorf (UKE), Department of Pediatric Surgery","PRINCIPAL_INVESTIGATOR",{"name":30,"affiliation":31,"role":28},"Martin Lacher, Prof. Dr. med.","University of Leipzig, Department of Pediatric Surgery",[33,38],{"name":30,"role":34,"phone":35,"phoneExt":36,"email":37},"CONTACT","+49-341-97","26400","muc-fire-leipzig@medizin.uni-leipzig.de",{"name":26,"role":34,"phone":39,"phoneExt":40,"email":41},"+49-176","20192676","O.Madadi-Sanjani@uke.de",[43,59,71,86,99,110,123,132,145,156,166,177,189,202,214,225,239],{"facility":44,"status":45,"city":46,"state":18,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Universitätsklinik für Kinder- und Jugendchirurgie","RECRUITING","Graz","8036","Austria","AT",{"type":51,"coordinates":52},"Point",[53,54],15.44197,47.06733,{"lat":54,"lon":53},[57],{"name":58,"role":34,"phone":18,"phoneExt":18,"email":18},"Holger Till, Univ. Prof.",{"facility":60,"status":45,"city":61,"state":18,"zip":62,"country":48,"countryCode":49,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"Universitätsklinik für Kinder- und Jugendheilkunde","Vienna","1090",{"type":51,"coordinates":64},[65,66],16.37208,48.20849,{"lat":66,"lon":65},[69],{"name":70,"role":34,"phone":18,"phoneExt":18,"email":18},"Christoph Binder, Dr.",{"facility":72,"status":45,"city":73,"state":74,"zip":75,"country":76,"countryCode":77,"cosmosGeoPoint":78,"geoPoint":82,"contacts":83},"Universitätsklinik für Kinder- und Jugendmedizin Tübingen","Tübingen","Baden-Wurttemberg","72076","Germany","DE",{"type":51,"coordinates":79},[80,81],9.05222,48.52266,{"lat":81,"lon":80},[84],{"name":85,"role":34,"phone":18,"phoneExt":18,"email":18},"Christian Poets, Prof. Dr.",{"facility":87,"status":45,"city":88,"state":89,"zip":90,"country":76,"countryCode":77,"cosmosGeoPoint":91,"geoPoint":95,"contacts":96},"Städtisches Klinikum München GmbH\u002F Klinikum Schwabing","München","Bavaria","80804",{"type":51,"coordinates":92},[93,94],13.46314,48.69668,{"lat":94,"lon":93},[97],{"name":98,"role":34,"phone":18,"phoneExt":18,"email":18},"Stuart Hosie, Prof. Dr.",{"facility":100,"status":101,"city":102,"state":103,"zip":104,"country":76,"countryCode":77,"cosmosGeoPoint":105,"geoPoint":109,"contacts":18},"Zentrum der Chirurgie, Klinik für Kinderchirurgie","TERMINATED","Frankfurt am Main","Hesse","60590",{"type":51,"coordinates":106},[107,108],8.68417,50.11552,{"lat":108,"lon":107},{"facility":111,"status":45,"city":112,"state":113,"zip":114,"country":76,"countryCode":77,"cosmosGeoPoint":115,"geoPoint":119,"contacts":120},"Auf der Bult, Kinder- und Jugendkrankenhaus, Kinderchirurgie und Kinderurologie","Hanover","Lower Saxony","30173",{"type":51,"coordinates":116},[117,118],9.73322,52.37052,{"lat":118,"lon":117},[121],{"name":122,"role":34,"phone":18,"phoneExt":18,"email":18},"Barbara Ludwikowski, PD Dr.",{"facility":124,"status":45,"city":112,"state":113,"zip":125,"country":76,"countryCode":77,"cosmosGeoPoint":126,"geoPoint":128,"contacts":129},"Hannover Medical School, Clinic for Pediatric Surgery","30625",{"type":51,"coordinates":127},[117,118],{"lat":118,"lon":117},[130],{"name":131,"role":34,"phone":18,"phoneExt":18,"email":18},"Julia Brendel, PD Dr. med.",{"facility":133,"status":45,"city":134,"state":135,"zip":136,"country":76,"countryCode":77,"cosmosGeoPoint":137,"geoPoint":141,"contacts":142},"Marien Hospital Witten, Ruhr-University Bochum, Department of Pediatric Surgery","Witten","North Rhine-Westphalia","58452",{"type":51,"coordinates":138},[139,140],7.35258,51.44362,{"lat":140,"lon":139},[143],{"name":144,"role":34,"phone":18,"phoneExt":18,"email":18},"Jochen Hubertus, Prof. Dr.",{"facility":146,"status":147,"city":148,"state":149,"zip":150,"country":76,"countryCode":77,"cosmosGeoPoint":151,"geoPoint":155,"contacts":18},"Universitätsmedizin Mainz, Klinik und Poliklinik für Kinderchirurgie","WITHDRAWN","Mainz","Rhineland-Palatinate","55131",{"type":51,"coordinates":152},[153,154],8.28008,49.98185,{"lat":154,"lon":153},{"facility":157,"status":101,"city":158,"state":159,"zip":160,"country":76,"countryCode":77,"cosmosGeoPoint":161,"geoPoint":165,"contacts":18},"Universitätsklinikum Carl Gustav Carus, Klinik und Poliklinik für Kinderchirurgie","Dresden","Saxony","01304",{"type":51,"coordinates":162},[163,164],13.73832,51.05089,{"lat":164,"lon":163},{"facility":5,"status":45,"city":167,"state":159,"zip":168,"country":76,"countryCode":77,"cosmosGeoPoint":169,"geoPoint":173,"contacts":174},"Leipzig","04103",{"type":51,"coordinates":170},[171,172],12.37129,51.33962,{"lat":172,"lon":171},[175],{"name":176,"role":34,"phone":18,"phoneExt":18,"email":37},"Martin Lacher, Prof. Dr.",{"facility":178,"status":45,"city":179,"state":18,"zip":180,"country":76,"countryCode":77,"cosmosGeoPoint":181,"geoPoint":185,"contacts":186},"University Hospital Augsburg, Clinic for Pediatric Surgery","Augsburg","86156",{"type":51,"coordinates":182},[183,184],10.89851,48.37154,{"lat":184,"lon":183},[187],{"name":188,"role":34,"phone":18,"phoneExt":18,"email":18},"Tobias Schuster, Dr. med.",{"facility":190,"status":191,"city":192,"state":18,"zip":193,"country":76,"countryCode":77,"cosmosGeoPoint":194,"geoPoint":198,"contacts":199},"Hamburg [University Hospital Hamburg Eppendorf\u002FUKE & Altonaer Kinderkrankenhaus\u002FAKK]","NOT_YET_RECRUITING","Hamburg","20246",{"type":51,"coordinates":195},[196,197],9.99302,53.55073,{"lat":197,"lon":196},[200],{"name":201,"role":34,"phone":18,"phoneExt":18,"email":18},"Konrad Reinshagen, Prof. Dr.",{"facility":203,"status":45,"city":204,"state":18,"zip":205,"country":76,"countryCode":77,"cosmosGeoPoint":206,"geoPoint":210,"contacts":211},"University Hospital Marburg, Clinic for Pediatric Surgery","Marburg","35043",{"type":51,"coordinates":207},[208,209],8.77069,50.80904,{"lat":209,"lon":208},[212],{"name":213,"role":34,"phone":18,"phoneExt":18,"email":18},"Guido Seitz, Prof. Dr.",{"facility":215,"status":45,"city":88,"state":18,"zip":216,"country":76,"countryCode":77,"cosmosGeoPoint":217,"geoPoint":221,"contacts":222},"Munich Clinic Harlaching","81545",{"type":51,"coordinates":218},[219,220],13.31243,51.60698,{"lat":220,"lon":219},[223],{"name":224,"role":34,"phone":18,"phoneExt":18,"email":18},"Marcus Krüger, Prof. Dr. med.",{"facility":226,"status":45,"city":227,"state":18,"zip":228,"country":229,"countryCode":230,"cosmosGeoPoint":231,"geoPoint":235,"contacts":236},"Amsterdam University Medical Centers","Amsterdam","1000 GG","Netherlands","NL",{"type":51,"coordinates":232},[233,234],4.88969,52.37403,{"lat":234,"lon":233},[237],{"name":238,"role":34,"phone":18,"phoneExt":18,"email":18},"Ernest van Heurn, Prof. Dr.",{"facility":240,"status":45,"city":241,"state":18,"zip":242,"country":229,"countryCode":230,"cosmosGeoPoint":243,"geoPoint":247,"contacts":248},"Erasmus University Medical Center Rotterdam","Rotterdam","3015 CE",{"type":51,"coordinates":244},[245,246],4.47917,51.9225,{"lat":246,"lon":245},[249],{"name":250,"role":34,"phone":18,"phoneExt":18,"email":18},"H.R. (Hester) Langeveld-Benders, Dr.",{"type":28,"investigatorFullName":252,"investigatorTitle":253,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Martin Lacher","Prof. Dr. med.",[255,257],{"name":256,"class":6},"German Research Foundation",{"name":258,"class":6},"Hannover Medical School","100321802","mucous-fistula-refeeding-reduces-the-time-from-enterostomy-closure-to-full-enteral-feeds-muc-fire-trial-100321802",false,"NCT03469609","Mucous Fistula Refeeding Reduces the Time From Enterostomy Closure to Full Enteral Feeds (\"MUC-FIRE\" Trial)","A Randomized Multicenter Open-label Controlled Trial to Show That Mucous Fistula Refeeding Reduces the Time From Enterostomy Closure to Full Enteral Feeds (MUCous FIstula REfeeding (\"MUC-FIRE\") Trial)","MUC-FIRE","Inclusion Criteria:\n\n1. Infants \\\u003C 366 days,\n2. Ileostomy \u002F Jejunostomy,\n3. double loop enterostomies and split enterostomies (with mucous fistula)\n4. Signed written informed consent obtained by parents\u002Flegal guardians and willingness of parents\u002Flegal guardians to comply with treatment and follow-up procedures of their child\n\nExclusion Criteria:\n\n1. resection of ileocecal valve,\n2. colostomy,\n3. small bowel atresia,\n4. multiple ostomies (more than just an enterostomy and a mucous fistula),\n5. chromosomal abnormalities (if known at the time of randomization),\n6. Hirschsprung's disease,\n7. participation in another drug-intervention study\n8. Intestinal perforation due to a hemodynamic heart defect","ALL","12 Months",{"count":270,"type":271},120,"ESTIMATED","INTERVENTIONAL",[274],"NA","The primary objective of this study is to demonstrate that mucous fistula refeeding between enterostomy creation and enterostomy closure reduces the time to full enteral feeds after enterostomy closure compared to standard of care.",[277],"Enterostomy",[279,280,281,282,283,284,285,286,287,288,289,290],"infants","necrotizing enterocolitis (NEC)","focal intestinal perforation (FIP)","enterostomy creation","bowel reanastomosis","enteral feeding","caloric intake","parenteral nutrition","complication rate","reduction of hospital expenses","length of hospital stay","refeeding","2026-04-27",{"date":293,"type":294},"2026-05-01","ACTUAL",{"date":296,"type":294},"2018-06-18",{"date":298,"type":271},"2027-12",{"name":5,"class":6},17]