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Scheduled to or received solid organ transplant within 7 days before or after enrollment\n* Participant is receiving care at the time of enrollment at one of the study participating institutions.\n* Parent\u002Fguardian willing and able to provide informed consent, and if appropriate, child willing and able to provide informed assent.\n\nDonor Inclusion Criteria\n\n* Donor for HCT recipient enrolled on the VIPER study.\n* Willing and able to provide informed consent.\n\nExclusion Criteria:\n\nRecipient Exclusion Criteria\n\nNone\n\nDonor Exclusion Criteria\n\n* Is not an HCT donor for a participant enrolled on the VIPER study.\n* Not available to provide pre-transplant research blood sample.","ALL","18 Years",{"count":454,"type":455},2000,"ESTIMATED","OBSERVATIONAL","The participants are being asked to take part in this clinical trial, a type of research study, because the participants are scheduled to receive or have recently received a hematopoietic cell transplant (HCT) or a solid organ transplant (SOT).\n\nPrimary Objective\n\nTo determine if pre-transplant screening for respiratory viral load predicts RVI within 1- year post-transplant among survivors.\n\nSecondary Objectives:\n\n* To develop and validate a classifier based on pre-transplant immunological profile predictive of developing an acute respiratory viral infection (aRVI), with RSV\u002FPIV3\u002FHMPV\u002FSARS-CoV-2 through one-year post-transplant among survivors.\n* To develop and validate a classifier based on Day +100 post-transplant immunological profiles predictive of developing an acute respiratory viral infection (aRVI),with RSV\u002FPIV3\u002FHMPV\u002FSARS-CoV-2 through one-year post-transplant among survivors .",[459,460,461],"Hematopoietic Cell Transplant","Solid Organ Transplant","Respiratory Viral Infection","2025-09-29",{"date":464,"type":465},"2025-10-02","ACTUAL",{"date":467,"type":465},"2022-12-13",{"date":469,"type":455},"2029-08",{"name":5,"class":6},27]