[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642892":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":18,"locations":24,"responsibleParty":53,"collaborators":10,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":10,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":10,"studyType":68,"phases":10,"briefSummary":69,"conditions":70,"keywords":10,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Claris Biotherapeutics, Inc.","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Non-interventional",null,"No product administration.",[13],"Other: Non-interventional",[15],{"type":16,"name":9,"description":9,"armGroupLabels":17,"otherNames":10},"OTHER",[9],[19],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Central Operations Representative","CONTACT","919-205-0012","clinicaltrials@clarisbio.com",[25,42],{"facility":26,"status":27,"city":28,"state":29,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Midwest Cornea Associates, LLC","RECRUITING","Carmel","Indiana","46290","United States","US",{"type":34,"coordinates":35},"Point",[36,37],-86.11804,39.97837,{"lat":37,"lon":36},[40],{"name":41,"role":21,"phone":10,"phoneExt":10,"email":10},"Study Coordinator",{"facility":43,"status":27,"city":44,"state":29,"zip":45,"country":31,"countryCode":32,"cosmosGeoPoint":46,"geoPoint":50,"contacts":51},"Francis Price Jr, MD","Indianapolis","46260",{"type":34,"coordinates":47},[48,49],-86.15804,39.76838,{"lat":49,"lon":48},[52],{"name":41,"role":21,"phone":10,"phoneExt":10,"email":10},{"type":54,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100642892","multi-center-prospective-non-interventional-study-in-subjects-with-limbal-stem-cell-deficiency-100642892",false,"NCT07636590","Multi-Center, Prospective, Non-Interventional Study in Subjects With Limbal Stem Cell Deficiency","A Multi-Center, Prospective, Non-Interventional Study in Subjects With Limbal Stem Cell Deficiency","Inclusion Criteria:\n\n* A photopic BCVA in the prospective study eye(s) of ≤ 70 letters at the Screening and Day 1 visits AND a change of ≤ 10 letters in photopic BCVA at Day 1 compared to the Screening Visit\n* Qualifying LSCD diagnosis in the study eye(s) prior to enrollment at Day 1\n* Written confirmation that exclusions on retinal findings are met in the study eye(s) prior to enrollment at Day 1\n* Inflammation associated with LSCD or other non-infectious inflammation (e.g., dry eye, ocular rosacea, and blepharitis) that will not interfere with the subject's participation in the opinion of the investigator is permitted.\n\nExclusion Criteria:\n\n* Any active ocular infection in either eye at either the Screening or Day 1 visits\n* Active sterile iritis or uveitis in either eye at Screening or Day 1 visits\n* Screening visit retinal exam finding, in the opinion of the investigator, that would limit potential for visual acuity gain in the study eye(s)\n\nNote: Other inclusion\u002Fexclusion criteria apply.","ALL","12 Years","99 Years",{"count":66,"type":67},500,"ESTIMATED","OBSERVATIONAL","The goal of this non-interventional, observational study is to describe the natural history, clinical course, and management patterns of subjects with limbal stem cell deficiency (LSCD).",[71],"Limbal Stem Cell Deficiency","2026-06-03",{"date":74,"type":75},"2026-06-09","ACTUAL",{"date":77,"type":75},"2026-05-22",{"date":79,"type":67},"2028-03",{"name":5,"class":6},2]