[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586150":3},{"organization":4,"armGroups":7,"interventions":28,"overallOfficials":34,"centralContacts":44,"locations":50,"responsibleParty":534,"collaborators":536,"id":539,"slug":540,"hasResults":541,"nctId":542,"briefTitle":543,"officialTitle":544,"acronym":545,"eligibilityCriteria":546,"healthyVolunteers":541,"sex":547,"minAge":548,"maxAge":34,"enrollmentInfo":549,"targetDuration":34,"studyType":552,"phases":553,"briefSummary":555,"conditions":556,"keywords":559,"overallStatus":53,"whyStopped":34,"lastUpdateSubmitDate":561,"lastUpdatePostDateStruct":562,"startDateStruct":565,"completionDateStruct":567,"leadSponsor":569,"locationsCount":570},{"fullName":5,"class":6},"Tempus AI","INDUSTRY",[8,15,19,25],{"label":9,"type":10,"description":11,"interventionNames":12},"High Risk Device","EXPERIMENTAL","The device result will be returned to the treating provider and participants will undergo a study sponsored diagnostic work-up consisting of a transthoracic echocardiogram and an RHC.",[13,14],"Device: ECG-based AI Device - Results Returned to Investigator","Procedure: Echocardiogram and Right Heart Catheterization",{"label":16,"type":10,"description":17,"interventionNames":18},"Not High Risk Device","The device result will be returned to the treating provider. Participants will continue to be evaluated for PH according to the current standard of care with any diagnostic procedures ordered at the discretion of the treating provider.",[13],{"label":20,"type":21,"description":22,"interventionNames":23},"High Risk Control Arm","OTHER","The device result will not be returned to the treating provider. Participants will continue to be evaluated for PH according to the current standard of care with any diagnostic procedures ordered at the discretion of the treating provider.",[24],"Device: ECG-based AI Device - Results Not Returned to Investigator",{"label":26,"type":21,"description":22,"interventionNames":27},"Not High Risk Control Arm",[24],[29,35,40],{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"DEVICE","ECG-based AI Device - Results Returned to Investigator","An ECG-based AI device that predicts undiagnosed PH using data from a 12-lead ECG. Device results will be returned to the Investigators.",[9,16],null,{"type":36,"name":37,"description":38,"armGroupLabels":39,"otherNames":34},"PROCEDURE","Echocardiogram and Right Heart Catheterization","Echocardiogram- an ultrasound study of the heart and Right Heart Catheterization- a procedure to measure pressures in the heart",[9],{"type":30,"name":41,"description":42,"armGroupLabels":43,"otherNames":34},"ECG-based AI Device - Results Not Returned to Investigator","An ECG-based AI device that predicts undiagnosed PH using data from a 12-lead ECG. Device results will not be returned to the Investigators.",[20,26],[45],{"name":46,"role":47,"phone":48,"phoneExt":34,"email":49},"Momentous Study","CONTACT","(833) 514-4187","momentous-study@tempus.com",[51,73,90,103,120,137,154,166,183,192,209,226,242,259,276,292,309,326,343,356,373,390,407,424,437,454,471,488,500,517],{"facility":52,"status":53,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"University of Alabama at Birmingham","RECRUITING","Birmingham","Alabama","35205","United States","US",{"type":60,"coordinates":61},"Point",[62,63],-86.80249,33.52066,{"lat":63,"lon":62},[66,70],{"name":67,"role":47,"phone":68,"phoneExt":34,"email":69},"Andrea Ford","205-0934-8904","afcook@uabmc.edu",{"name":71,"role":72,"phone":34,"phoneExt":34,"email":34},"Meenakshi Sridhar, MD","PRINCIPAL_INVESTIGATOR",{"facility":74,"status":53,"city":75,"state":76,"zip":77,"country":57,"countryCode":58,"cosmosGeoPoint":78,"geoPoint":82,"contacts":83},"Banner University Medical Center","Phoenix","Arizona","84006",{"type":60,"coordinates":79},[80,81],-112.07404,33.44838,{"lat":81,"lon":80},[84,88],{"name":85,"role":47,"phone":86,"phoneExt":34,"email":87},"Clinical Research Coordinator","602-521-6400","slmarch@arizona.edu",{"name":89,"role":72,"phone":34,"phoneExt":34,"email":34},"Sally Suliman, MD",{"facility":91,"status":53,"city":75,"state":76,"zip":92,"country":57,"countryCode":58,"cosmosGeoPoint":93,"geoPoint":95,"contacts":96},"Dignity Health - St. Joseph's Hospital and Medical Center-Norton Thoracic Institute","85013",{"type":60,"coordinates":94},[80,81],{"lat":81,"lon":80},[97,101],{"name":98,"role":47,"phone":99,"phoneExt":34,"email":100},"Dominique Robertson","602-406-1295","dominique.robertson900@commonspirit.org",{"name":102,"role":72,"phone":34,"phoneExt":34,"email":34},"Rajat Walia, MD",{"facility":104,"status":53,"city":105,"state":106,"zip":107,"country":57,"countryCode":58,"cosmosGeoPoint":108,"geoPoint":112,"contacts":113},"National Jewish Health","Denver","Colorado","80206",{"type":60,"coordinates":109},[110,111],-104.9847,39.73915,{"lat":111,"lon":110},[114,118],{"name":115,"role":47,"phone":116,"phoneExt":34,"email":117},"Adrea Arthofer","720-945-8608","arthofera@NJHealth.org",{"name":119,"role":72,"phone":34,"phoneExt":34,"email":34},"Joshua Solomon, MD",{"facility":121,"status":53,"city":122,"state":123,"zip":124,"country":57,"countryCode":58,"cosmosGeoPoint":125,"geoPoint":129,"contacts":130},"AdventHealth Orlando","Orlando","Florida","32803",{"type":60,"coordinates":126},[127,128],-81.37924,28.53834,{"lat":128,"lon":127},[131,135],{"name":132,"role":47,"phone":133,"phoneExt":34,"email":134},"Kimberly Stark","407-303-9984","kimberly.stark@adventhealth.com",{"name":136,"role":72,"phone":34,"phoneExt":34,"email":34},"Onix Cantres-Fonseca, MD",{"facility":138,"status":53,"city":139,"state":140,"zip":141,"country":57,"countryCode":58,"cosmosGeoPoint":142,"geoPoint":146,"contacts":147},"Northwestern University","Chicago","Illinois","60611",{"type":60,"coordinates":143},[144,145],-87.65005,41.85003,{"lat":145,"lon":144},[148,152],{"name":149,"role":47,"phone":150,"phoneExt":34,"email":151},"Taryn Holt","312-503-2157","taryn.holt@northwestern.edu",{"name":153,"role":72,"phone":34,"phoneExt":34,"email":34},"Ruben Mylvaganam, MD",{"facility":155,"status":53,"city":139,"state":140,"zip":156,"country":57,"countryCode":58,"cosmosGeoPoint":157,"geoPoint":159,"contacts":160},"University of Illinois Health","60612",{"type":60,"coordinates":158},[144,145],{"lat":145,"lon":144},[161,165],{"name":162,"role":47,"phone":163,"phoneExt":34,"email":164},"Dustin Fraidenburg, MD","866-600-2273","dfraiden@uic.edu",{"name":162,"role":72,"phone":34,"phoneExt":34,"email":34},{"facility":167,"status":53,"city":168,"state":169,"zip":170,"country":57,"countryCode":58,"cosmosGeoPoint":171,"geoPoint":175,"contacts":176},"Indiana University Health Methodist Hospital","Indianapolis","Indiana","46202",{"type":60,"coordinates":172},[173,174],-86.15804,39.76838,{"lat":174,"lon":173},[177,181],{"name":178,"role":47,"phone":179,"phoneExt":34,"email":180},"Isabell Mwaura","317-274-0822","imwaura@iu.edu",{"name":182,"role":72,"phone":34,"phoneExt":34,"email":34},"Onydika Ilonze, MD",{"facility":184,"status":53,"city":168,"state":169,"zip":185,"country":57,"countryCode":58,"cosmosGeoPoint":186,"geoPoint":188,"contacts":189},"Community Health Network","46237",{"type":60,"coordinates":187},[173,174],{"lat":174,"lon":173},[190],{"name":191,"role":72,"phone":34,"phoneExt":34,"email":34},"Satish Krishnan, MD",{"facility":193,"status":53,"city":194,"state":195,"zip":196,"country":57,"countryCode":58,"cosmosGeoPoint":197,"geoPoint":201,"contacts":202},"University of Kentucky","Lexington","Kentucky","40536",{"type":60,"coordinates":198},[199,200],-84.47772,37.98869,{"lat":200,"lon":199},[203,207],{"name":204,"role":47,"phone":205,"phoneExt":34,"email":206},"Srushan Bhaktula","859-323-5000","ssh486@uky.edu",{"name":208,"role":72,"phone":34,"phoneExt":34,"email":34},"Michael Powers, MD",{"facility":210,"status":53,"city":211,"state":212,"zip":213,"country":57,"countryCode":58,"cosmosGeoPoint":214,"geoPoint":218,"contacts":219},"Louisiana State University Health Shreveport","Shreveport","Louisiana","71102",{"type":60,"coordinates":215},[216,217],-93.75018,32.52515,{"lat":217,"lon":216},[220,224],{"name":221,"role":47,"phone":222,"phoneExt":34,"email":223},"Teresa Leeth","318-675-5920","teresa.leeth@lsuhs.edu",{"name":225,"role":72,"phone":34,"phoneExt":34,"email":34},"Afsana Asharaf, MD",{"facility":227,"status":53,"city":228,"state":229,"zip":230,"country":57,"countryCode":58,"cosmosGeoPoint":231,"geoPoint":235,"contacts":236},"Brigham and Women's Hospital","Boston","Massachusetts","02115",{"type":60,"coordinates":232},[233,234],-71.05977,42.35843,{"lat":234,"lon":233},[237,240],{"name":85,"role":47,"phone":238,"phoneExt":34,"email":239},"970-846-2343","eharris@bwh.harvard.edu",{"name":241,"role":72,"phone":34,"phoneExt":34,"email":34},"Aaron Waxman, MD",{"facility":243,"status":53,"city":244,"state":245,"zip":246,"country":57,"countryCode":58,"cosmosGeoPoint":247,"geoPoint":251,"contacts":252},"University of Michigan - Michigan Medicine","Ann Arbor","Michigan","48109-5360",{"type":60,"coordinates":248},[249,250],-83.74088,42.27756,{"lat":250,"lon":249},[253,257],{"name":254,"role":47,"phone":255,"phoneExt":34,"email":256},"Catherine Crombez","734-232-4176","cathercr@med.umich.edu",{"name":258,"role":72,"phone":34,"phoneExt":34,"email":34},"Elizabeth Belloli, MD",{"facility":260,"status":53,"city":261,"state":262,"zip":263,"country":57,"countryCode":58,"cosmosGeoPoint":264,"geoPoint":268,"contacts":269},"University of Minnesota","Minneapolis","Minnesota","55455",{"type":60,"coordinates":265},[266,267],-93.26384,44.97997,{"lat":267,"lon":266},[270,274],{"name":271,"role":47,"phone":272,"phoneExt":34,"email":273},"Mandi DeGrote","612-626-7609","carl1032@umn.edu",{"name":275,"role":72,"phone":34,"phoneExt":34,"email":34},"Anupam Kumar, MD",{"facility":277,"status":53,"city":278,"state":279,"zip":280,"country":57,"countryCode":58,"cosmosGeoPoint":281,"geoPoint":285,"contacts":286},"Hannibal Regional Healthcare System","Hannibal","Missouri","63401",{"type":60,"coordinates":282},[283,284],-91.35848,39.70838,{"lat":284,"lon":283},[287,290],{"name":34,"role":47,"phone":288,"phoneExt":34,"email":289},"573-629-3926","humam.farah@hannibalclinic.com",{"name":291,"role":72,"phone":34,"phoneExt":34,"email":34},"Humam Farah, MD",{"facility":293,"status":53,"city":294,"state":295,"zip":296,"country":57,"countryCode":58,"cosmosGeoPoint":297,"geoPoint":301,"contacts":302},"CHI Health Creighton University Medical Center - Bergan Mercy","Omaha","Nebraska","68124",{"type":60,"coordinates":298},[299,300],-95.94043,41.25626,{"lat":300,"lon":299},[303,307],{"name":304,"role":47,"phone":305,"phoneExt":34,"email":306},"Chloe Andersen","402-343-8511","chloe.andersen900@commonspirit.org",{"name":308,"role":72,"phone":34,"phoneExt":34,"email":34},"Alexander Staller, MD",{"facility":310,"status":53,"city":311,"state":312,"zip":313,"country":57,"countryCode":58,"cosmosGeoPoint":314,"geoPoint":318,"contacts":319},"Renown Regional Medical Center","Reno","Nevada","89502",{"type":60,"coordinates":315},[316,317],-119.8138,39.52963,{"lat":317,"lon":316},[320,324],{"name":321,"role":47,"phone":322,"phoneExt":34,"email":323},"Merlino","775-982-7878","amanda.merlino@renown.org",{"name":325,"role":72,"phone":34,"phoneExt":34,"email":34},"Farah Madhani-Lovely, MD",{"facility":327,"status":53,"city":328,"state":329,"zip":330,"country":57,"countryCode":58,"cosmosGeoPoint":331,"geoPoint":335,"contacts":336},"University of New Mexico","Albuquerque","New Mexico","87131",{"type":60,"coordinates":332},[333,334],-106.65114,35.08449,{"lat":334,"lon":333},[337,341],{"name":338,"role":47,"phone":339,"phoneExt":34,"email":340},"Goodale","505-272-6794","LGoodale@salud.unm.edu",{"name":342,"role":72,"phone":34,"phoneExt":34,"email":34},"Tariq Sallam, MD",{"facility":344,"status":53,"city":345,"state":346,"zip":347,"country":57,"countryCode":58,"cosmosGeoPoint":348,"geoPoint":352,"contacts":353},"University of Buffalo","Buffalo","New York","14203",{"type":60,"coordinates":349},[350,351],-78.87837,42.88645,{"lat":351,"lon":350},[354],{"name":355,"role":72,"phone":34,"phoneExt":34,"email":34},"Kristopher Clark, MD",{"facility":357,"status":53,"city":358,"state":359,"zip":360,"country":57,"countryCode":58,"cosmosGeoPoint":361,"geoPoint":365,"contacts":366},"Southeastern Research Center","Winston-Salem","North Carolina","27103",{"type":60,"coordinates":362},[363,364],-80.24422,36.09986,{"lat":364,"lon":363},[367,371],{"name":368,"role":47,"phone":369,"phoneExt":34,"email":370},"Lauren Miller","336-659-8414","lmiller@southeasternresearchcenter.com",{"name":372,"role":72,"phone":34,"phoneExt":34,"email":34},"Hassan Yousaf, MD",{"facility":374,"status":53,"city":375,"state":376,"zip":377,"country":57,"countryCode":58,"cosmosGeoPoint":378,"geoPoint":382,"contacts":383},"University Hospitals Cleveland Medical Center","Cleveland","Ohio","44121",{"type":60,"coordinates":379},[380,381],-81.69541,41.4995,{"lat":381,"lon":380},[384,388],{"name":385,"role":47,"phone":386,"phoneExt":34,"email":387},"Jennie Pexa","216-844-3201","jennie.pexa@uhhospitals.org",{"name":389,"role":72,"phone":34,"phoneExt":34,"email":34},"Maroun Matta, MD",{"facility":391,"status":53,"city":392,"state":393,"zip":394,"country":57,"countryCode":58,"cosmosGeoPoint":395,"geoPoint":399,"contacts":400},"University of Oklahoma","Oklahoma City","Oklahoma","73104",{"type":60,"coordinates":396},[397,398],-97.51643,35.46756,{"lat":398,"lon":397},[401,405],{"name":402,"role":47,"phone":403,"phoneExt":34,"email":404},"Maria Mason","405-271-6173","Maria-l-mason@ouhsc.edu",{"name":406,"role":72,"phone":34,"phoneExt":34,"email":34},"Jad Kebbe, MD",{"facility":408,"status":53,"city":409,"state":410,"zip":411,"country":57,"countryCode":58,"cosmosGeoPoint":412,"geoPoint":416,"contacts":417},"Thomas Jefferson University","Philadelphia","Pennsylvania","19107",{"type":60,"coordinates":413},[414,415],-75.16362,39.95238,{"lat":415,"lon":414},[418,422],{"name":419,"role":47,"phone":420,"phoneExt":34,"email":421},"Mallem","215-955-9181","djamila.mallem@jefferson.edu",{"name":423,"role":72,"phone":34,"phoneExt":34,"email":34},"Gautam George, MD",{"facility":425,"status":53,"city":409,"state":410,"zip":426,"country":57,"countryCode":58,"cosmosGeoPoint":427,"geoPoint":429,"contacts":430},"Temple University of The Commonwealth System of Higher Education","19140",{"type":60,"coordinates":428},[414,415],{"lat":415,"lon":414},[431,435],{"name":432,"role":47,"phone":433,"phoneExt":34,"email":434},"Kimberly Selwood","215-707-2291","Kim.Selwood@tuhs.temple.edu",{"name":436,"role":72,"phone":34,"phoneExt":34,"email":34},"Parth Rali, MD",{"facility":438,"status":53,"city":439,"state":440,"zip":441,"country":57,"countryCode":58,"cosmosGeoPoint":442,"geoPoint":446,"contacts":447},"Medical University of South Carolina","Charleston","South Carolina","29425",{"type":60,"coordinates":443},[444,445],-79.93275,32.77632,{"lat":445,"lon":444},[448,452],{"name":449,"role":47,"phone":450,"phoneExt":34,"email":451},"Krishna","843-792-1794","georgjam@musc.edu",{"name":453,"role":72,"phone":34,"phoneExt":34,"email":34},"Rachana Krishna, MD",{"facility":455,"status":53,"city":456,"state":457,"zip":458,"country":57,"countryCode":58,"cosmosGeoPoint":459,"geoPoint":463,"contacts":464},"University of Tennessee","Knoxville","Tennessee","37920",{"type":60,"coordinates":460},[461,462],-83.92074,35.96064,{"lat":462,"lon":461},[465,469],{"name":466,"role":47,"phone":467,"phoneExt":34,"email":468},"Herbert","865-305-4893","bherbert@utmck.edu",{"name":470,"role":72,"phone":34,"phoneExt":34,"email":34},"Isaac Biney, MD",{"facility":472,"status":53,"city":473,"state":474,"zip":475,"country":57,"countryCode":58,"cosmosGeoPoint":476,"geoPoint":480,"contacts":481},"Baylor University Medical Center","Dallas","Texas","75246",{"type":60,"coordinates":477},[478,479],-96.80667,32.78306,{"lat":479,"lon":478},[482,486],{"name":483,"role":47,"phone":484,"phoneExt":34,"email":485},"Brianna Kamran","214-820-6856","Brianna.Kamran@bswhealth.org",{"name":487,"role":72,"phone":34,"phoneExt":34,"email":34},"Susan Mathai, MD",{"facility":489,"status":53,"city":490,"state":474,"zip":491,"country":57,"countryCode":58,"cosmosGeoPoint":492,"geoPoint":496,"contacts":497},"Baylor College of Medicine","Houston","77030",{"type":60,"coordinates":493},[494,495],-95.36327,29.76328,{"lat":495,"lon":494},[498],{"name":499,"role":72,"phone":34,"phoneExt":34,"email":34},"Ivan Rosas, MD",{"facility":501,"status":53,"city":502,"state":503,"zip":504,"country":57,"countryCode":58,"cosmosGeoPoint":505,"geoPoint":509,"contacts":510},"University of Utah","Salt Lake City","Utah","84103",{"type":60,"coordinates":506},[507,508],-111.89105,40.76078,{"lat":508,"lon":507},[511,515],{"name":512,"role":47,"phone":513,"phoneExt":34,"email":514},"Stefanos Lakonios","801-581-5811","stefan.lakonios@hsc.utah.edu",{"name":516,"role":72,"phone":34,"phoneExt":34,"email":34},"Matthew Glick, MD",{"facility":518,"status":53,"city":519,"state":520,"zip":521,"country":57,"countryCode":58,"cosmosGeoPoint":522,"geoPoint":526,"contacts":527},"West Virginia University Hospital","Morgantown","West Virginia","26505",{"type":60,"coordinates":523},[524,525],-79.9559,39.62953,{"lat":525,"lon":524},[528,532],{"name":529,"role":47,"phone":530,"phoneExt":34,"email":531},"Chad Glaze","304-293-4661","cglaze@hsc.wvu.edu",{"name":533,"role":72,"phone":34,"phoneExt":34,"email":34},"Himanshu Deshwal, MD",{"type":535,"investigatorFullName":34,"investigatorTitle":34,"investigatorAffiliation":34,"oldNameTitle":34,"oldOrganization":34},"SPONSOR",[537],{"name":538,"class":6},"United Therapeutics","100586150","multi-site-study-of-the-clinical-impact-of-an-ai-assisted-approach-to-referring-patients-with-interstitial-lung-disease-for-diagnostic-evaluation-of-pulmonary-hypertension-100586150",false,"NCT06911632","Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension","MOMENTOUS Study (iMpact Of an Ecg ai ModEl oN The Diagnosis Of pUlmonary hypertenSion)","MOMENTOUS","Inclusion Criteria:\n\n* 18 years or older at the time of consent\n* A known diagnosis of interstitial lung disease\n* Diffusing capacity for carbon monoxide (DLCO) \\\u003C30% predicted, collected within 3 months prior to consent\n* Willing and able to provide informed consent and undergo all study-specific procedures, including echo and RHC, if required\n\nExclusion Criteria:\n\n* A known diagnosis of pulmonary hypertension (including patients prescribed a therapy specifically for pulmonary arterial hypertension (PAH))\n* A RHC was completed within the previous 1 year or ordered and not yet completed at the time of consent\n* LV ejection fraction ≤ 40% on most recent echo or cardiac MRI, if available\n* Unclassifiable Tempus PH ECG risk result after up to 2 ECG acquisitions\n* A contraindication to RHC exists (for example, pregnancy or mechanical right heart valve)\n* Physician decision that if a patient is directed to RHC by the study protocol, the potential risks of RHC outweigh the potential benefits\n* There is a severe concomitant illness limiting life expectancy to less than 6 months (at the discretion of the investigator)\n* There is a medical or social factor that makes the patient a poor candidate for the study and\u002For unlikely to be able to comply with the study protocol or complete study procedures (at the discretion of the investigator)","ALL","18 Years",{"count":550,"type":551},900,"ESTIMATED","INTERVENTIONAL",[554],"NA","MOMENTOUS is a multi-center, randomized study to prospectively evaluate the performance of an ECG-based AI device to predict whether participants with interstitial lung disease (ILD) are at high risk of undiagnosed pulmonary hypertension.",[557,558],"Pulmonary Hypertension","Interstitial Lung Disease (ILD)",[557,560],"Interstitial lung disease (ILD)","2026-06-30",{"date":563,"type":564},"2026-07-02","ACTUAL",{"date":566,"type":564},"2025-07-23",{"date":568,"type":551},"2028-07",{"name":5,"class":6},30]