[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643039":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":28,"responsibleParty":86,"collaborators":10,"id":89,"slug":90,"hasResults":91,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":10,"eligibilityCriteria":95,"healthyVolunteers":91,"sex":96,"minAge":97,"maxAge":10,"enrollmentInfo":98,"targetDuration":10,"studyType":101,"phases":10,"briefSummary":102,"conditions":103,"keywords":105,"overallStatus":49,"whyStopped":10,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":117},{"fullName":5,"class":6},"Capital Medical University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"post-intensive care syndrome group",null,"PICS patients who come from a general hospital ICU and are transferred to a participating HDU",[13],"Other: Data Collection and Assessment",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Data Collection and Assessment","1. General clinical data collection: demographic characteristics, primary disease, duration of tracheostomy tube retention, duration of mechanical ventilation before transfer, and length of ICU stay before transfer; history of organ dysfunction; tube\u002Fcatheter status; disease severity; nutritional status.\n2. Physical function assessment: diaphragmatic excursion, diaphragm thickness, thickening fraction, PEF; Medical Research Council score for muscle strength, ICU Mobility Scale; comprehensive score: Chelsea Critical Care Physical Assessment Tool score.\n3. Cognitive function assessment: Standardized Five Questions，Mini-Mental State Examination.\n4. Psychological status assessment: Patient Health Questionnaire-9 for depression, Generalized Anxiety Disorder 7-item scale , Pittsburgh Sleep Quality Index, Brief Pain Inventory-9, Hospital Anxiety and Depression Scale for family caregivers.\n5. Quality of life and functional capacity: Barthel Index, EQ-5D-5L.",[9],[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Jingyi Ge","CONTACT","+861056981098","ge_jingyi2020@163.com",{"name":26,"role":22,"phone":23,"phoneExt":10,"email":27},"Hongying Jiang, MD","6jhy@163.com",[29,47,62,71],{"facility":30,"status":31,"city":32,"state":33,"zip":10,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Anhui Wanbei Rehabilitation Hospital","NOT_YET_RECRUITING","Huaibei","Anhui","China","CN",{"type":37,"coordinates":38},"Point",[39,40],116.79167,33.97444,{"lat":40,"lon":39},[43],{"name":44,"role":22,"phone":45,"phoneExt":10,"email":46},"Weiwei Ge","15956181729","1790183840@qq.com",{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":34,"countryCode":35,"cosmosGeoPoint":53,"geoPoint":57,"contacts":58},"Beijing Rehabilitation Hospital, Capital Medical University, Beijing,China","RECRUITING","Beijing","Beijing Municipality","100043",{"type":37,"coordinates":54},[55,56],116.39723,39.9075,{"lat":56,"lon":55},[59],{"name":60,"role":22,"phone":61,"phoneExt":10,"email":27},"Hong ying Jiang","+8601056981555",{"facility":63,"status":31,"city":64,"state":64,"zip":65,"country":34,"countryCode":35,"cosmosGeoPoint":10,"geoPoint":10,"contacts":66},"Hunan Rehabilitation Hospital","Hunan","410000",[67],{"name":68,"role":22,"phone":69,"phoneExt":10,"email":70},"Pan Li","86-18674765825","584703769@qq.com",{"facility":72,"status":31,"city":73,"state":74,"zip":75,"country":34,"countryCode":35,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"Zhengzhou Central Hospital Affiliated to Zhengzhou University","Henan","Zhengzhou","450007",{"type":37,"coordinates":77},[78,79],112.22494,37.92189,{"lat":79,"lon":78},[82],{"name":83,"role":22,"phone":84,"phoneExt":10,"email":85},"Yajing Wang","86-15515645380","wangya568@163.com",{"type":87,"investigatorFullName":26,"investigatorTitle":88,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Sponsor-Investigator","100643039","multidimensional-dysfunction-in-patients-with-post-intensive-care-syndrome-in-china-100643039",false,"NCT07585578","Multidimensional Dysfunction in Patients With Post-Intensive Care Syndrome in China","Multidimensional Dysfunction in Patients With Post-Intensive Care Syndrome in China: A Multi-center Real-world Study","Inclusion Criteria:\n\n* Age ≥18 years\n* First admission to ICU, with ICU length of stay ≥ 48 hours before transfer to HDU\n* Complete the PICS assessment within 7 days after HDU admission\n* Complete clinical data available (demographics, ICU-related information)\n* Signed informed consent obtained from participants or legal guardians\n\nExclusion Criteria:\n\n* Prior ICU admission\n* Terminal illness or estimated life expectancy \\\u003C6 months\n* Participants or family members refuse to complete questionnaires","ALL","18 Years",{"count":99,"type":100},800,"ESTIMATED","OBSERVATIONAL","Over the past two decades, the rapid advancement of critical care medicine has significantly reduced short-term mortality among critically ill patients. However, a growing number of intensive care unit (ICU) survivors experience persistent physical, cognitive, and psychological impairments after hospital discharge, a syndrome termed post-intensive care syndrome (PICS). Although PICS has gained increasing attention in recent years, existing studies still have multiple limitations. Given the continuously increasing number of ICU survivors in China and the marked heterogeneity in critical care delivery models across different regions and healthcare institutions, there is an urgent need for large-scale multicenter observational studies to systematically characterize the epidemiological features, multidimensional functional impairment profiles, and clinical impact of PICS in Chinese patients, thereby providing an evidence-based foundation for the development of a scientific post-ICU continuum of care.",[104],"Post-Intensive Care Syndrome (PICS)",[104,106,107],"High-dependency unit","functional outcome","2026-06-09",{"date":110,"type":111},"2026-06-11","ACTUAL",{"date":113,"type":111},"2026-05-12",{"date":115,"type":100},"2027-05-31",{"name":26,"class":6},4]