[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637772":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":33,"locations":10,"responsibleParty":42,"collaborators":10,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":10,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":58,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":71,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":10},{"fullName":5,"class":6},"Poznan University of Physical Education","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Elite male rowers",null,"Male elite rowers aged 19-24 years performing standardized 2000-m and 6000-m rowing ergometer tests during two training phases. Exercise-related biological and psychophysiological responses will be assessed before exercise, immediately after exercise, and after 1 hour of recovery.",[13,14],"Other: 2000-m rowing ergometer test","Other: 6000-m rowing ergometer test",{"label":16,"type":10,"description":17,"interventionNames":18},"Elite female rowers","Female elite rowers aged 19-24 years performing standardized 2000-m and 6000-m rowing ergometer tests during two training phases. Exercise-related biological and psychophysiological responses will be assessed before exercise, immediately after exercise, and after 1 hour of recovery.",[13,14],[20,24],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"2000-m rowing ergometer test","A standardized maximal rowing ergometer exercise test performed over a distance of 2000 meters during the competitive phase of the training season to evaluate acute physiological and molecular responses to high-intensity exercise.",[16,9],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"6000-m rowing ergometer test","A standardized prolonged rowing ergometer exercise test performed over a distance of 6000 meters during the preparatory phase of the training season to evaluate physiological and molecular responses to prolonged submaximal exercise.",[16,9],[29],{"name":30,"affiliation":31,"role":32},"Anna Skarpańska-Stejborn, Professor","Poznan University of Physical Education, Gorzów Wielkopolski; Faculty of Sport Sciences in Gorzów Wielkopolski; Department of Biological Sciences,","PRINCIPAL_INVESTIGATOR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":10,"email":38},"Joanna Ostapiuk-Karolczuk, PhD","CONTACT","+48573337282","j.ostapiuk@awf-gorzow.edu.pl",{"name":40,"role":36,"phone":37,"phoneExt":10,"email":41},"Anna Kasperska, PhD","annakasperska.awf@gmail.com",{"type":43,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100637772","multilevel-exercise-response-in-rowers-100637772",false,"NCT07613619","Multilevel Exercise Response in Rowers","Multilevel Assessment of Physiological, Molecular, Metabolic, Intestinal, and Psychophysiological Responses to Rowing Ergometer Exercise in Competitive Rowers","Inclusion Criteria:\n\n* Male and female members of the Polish Youth National Rowing Team.\n* Age between 19 and 24 years.\n* Regular participation in structured rowing training.\n* Medical clearance for participation in maximal exercise testing.\n* Ability and willingness to provide written informed consent.\n\nExclusion Criteria:\n\n* Lack of consent for blood sampling or study participation.\n* Current injury or health condition contraindicating maximal exercise.\n* Acute infection, fever, or inflammatory condition at the time of testing.\n* Use of anti-inflammatory medications.\n* Use of performance-enhancing substances.\n* Use of dietary supplements within 3 months before study participation.\n* Any medical contraindications identified by the study physician.",true,"ALL","19 Years","24 Years",{"count":56,"type":57},30,"ESTIMATED","6 Months","OBSERVATIONAL","This observational study aims to evaluate multilevel physiological, molecular, metabolic, intestinal, immunological, and psychophysiological responses to rowing-specific exercise in elite rowers. The study is designed to investigate how maximal and prolonged rowing ergometer exercise influences integrated adaptive mechanisms related to mitochondrial function, metabolic regulation, intestinal permeability, immune activation, DNA damage response, and psychological status.\n\nThirty members of the Polish Youth National Rowing Team, aged 19-24 years, will participate in the study during two different training periods. During the competitive phase, participants will perform a 2000-m maximal rowing ergometer test, whereas during the preparatory phase they will complete a 6000-m rowing ergometer test. Blood samples and physiological measurements will be collected before exercise, immediately after exercise, and after 1 hour of recovery.\n\nThe study will assess gene expression, circulating biomarkers, flow cytometry parameters, blood morphology, lactate concentration, continuous glucose monitoring data, wearable metabolic sensor measurements, nutritional status, and psychological responses. The primary objective is to identify integrated biomarkers reflecting exercise load, recovery dynamics, and adaptive capacity in highly trained athletes. The study also aims to improve understanding of the interaction between metabolic, mitochondrial, intestinal, immunological, and psychophysiological responses to intensive exercise in rowing.",[62],"Healthy Adult Participants",[64,65,66,67,68,69,70],"Rowing","Exercise physiology","Mitochondrial function","Intestinal permeability","DNA damage response","Psychophysiology","Elite athletes","NOT_YET_RECRUITING","2026-05-21",{"date":74,"type":75},"2026-05-29","ACTUAL",{"date":77,"type":57},"2026-05-17",{"date":79,"type":57},"2027-01-30",{"name":5,"class":6}]