[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100402474":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":29,"centralContacts":34,"locations":40,"responsibleParty":55,"collaborators":38,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":60,"sex":66,"minAge":67,"maxAge":38,"enrollmentInfo":68,"targetDuration":38,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":38,"overallStatus":42,"whyStopped":38,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Institut Investigacio Sanitaria Pere Virgili","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"16W group","ACTIVE_COMPARATOR","Multimodal prehabilitation program (MPP) will be implemented during 16 weeks, 12 weeks during chemotherapy (CT) and 4 weeks while waiting for surgery.",[13],"Behavioral: Physical Prehabilitation",{"label":15,"type":10,"description":16,"interventionNames":17},"4W group","Multimodal prehabilitation program (MPP) will start at the end of preoperative chemotherapy (CT) until surgery (4 weeks in total).",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","Physical Prehabilitation","The prehabilitation program consists of the following interventions: in-hospital high-moderate intensive exercise training, nutritional assessment and high-protein supplementation, smoking cessation, psychological support and Comprehensive Geriatric Assessment.",[9,15],[25,26,27,28],"Nutritional intervention","Psychological intervention","Smoking cessation","Comprehensive Geriatric Assessment (CGA) and co-morbidity assessment",[30],{"name":31,"affiliation":32,"role":33},"Laia Estalella, PhD","Hospital Universitari de Tarragona Joan XXIII","PRINCIPAL_INVESTIGATOR",[35],{"name":31,"role":36,"phone":37,"phoneExt":38,"email":39},"CONTACT","+34 628164461",null,"laiaestalella2@gmail.com",[41],{"facility":32,"status":42,"city":43,"state":38,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Tarragona","43005","Spain","ES",{"type":48,"coordinates":49},"Point",[50,51],1.24544,41.11905,{"lat":51,"lon":50},[54],{"name":31,"role":36,"phone":37,"phoneExt":38,"email":39},{"type":33,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":38,"oldOrganization":38},"Laia Estalella Mercade","Principal Investigator","100402474","multimodal-prehabilitation-during-chemotherapy-in-patients-with-colorectal-liver-metastases-100402474",false,"NCT04520737","Multimodal Prehabilitation During Chemotherapy in Patients With Colorectal Liver Metastases","Multimodal Prehabilitation During Neoadjuvant Chemotherapy in Patients With Colorectal Liver Metastases: a Randomized Controlled Trial","PREHABMET","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Written informed consent obtained from subject to participate in the study.\n\nExclusion Criteria:\n\n* Age \\\u003C18 years\n* ASA health class status IV-V\n* Mental conditions or disabling orthopedic and neuromuscular disease that prevent physical exercise or may compromise adherence to the program\n* Medical contraindication to perform exercise\n* Inability to obtain informed consent","ALL","18 Years",{"count":69,"type":70},84,"ESTIMATED","INTERVENTIONAL",[73],"NA","Liver resection is the only curative treatment for patients with colorectal liver metastases (CRLM). Most patients undergo chemotherapy (CT) before liver surgery. CT objectively decreases patient functional capacity. It has already been demonstrated that a structured training program carried out during the 4 weeks following CT, while the patient is waiting for liver resection, is able to return the functional capacity to baseline levels. Despite this, multimodal prehabilitation programs (MPP) during preoperative CT have not been evaluated or implemented.\n\nThe aim of this study is to investigate whether a 16-week MPP applied during and following CT in CRLM patients will result in a significant increase in physical fitness when compared to those that undergo MPP only during the 4-weeks, between the end of CT and liver resection.",[76,77,78],"Prehabilitation","Neoadjuvant Therapy","Liver Metastases","2024-06-27",{"date":81,"type":82},"2024-07-01","ACTUAL",{"date":84,"type":82},"2021-02-01",{"date":86,"type":70},"2026-12-31",{"name":5,"class":6},1]