[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100575267":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":26,"locations":32,"responsibleParty":49,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":54,"sex":58,"minAge":59,"maxAge":10,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":10,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Chronic severe primary mitral regurgitation",null,"Adults with chronic severe primary mitral regurgitation undergoing robotic mitral annuloplasty at Mayo Clinic Rochester",[13],"Diagnostic Test: Cardiac MRI",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Cardiac MRI","Each subject will receive two cardiac MRI scans (with and without contrast), one preoperative and another 6-12 months after. The duration of each MRI is approximately 45-60 minutes",[9],[21,24],{"name":22,"affiliation":5,"role":23},"Arman Arghami, MD, MPH","PRINCIPAL_INVESTIGATOR",{"name":25,"affiliation":5,"role":23},"Alex Bratt, MD",[27],{"name":28,"role":29,"phone":30,"phoneExt":10,"email":31},"Cardiovascular Surgical Research","CONTACT","(507) 266-7982","cvsurgresearch@mayo.edu",[33],{"facility":5,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"RECRUITING","Rochester","Minnesota","55905","United States","US",{"type":41,"coordinates":42},"Point",[43,44],-92.4699,44.02163,{"lat":44,"lon":43},[47],{"name":28,"role":29,"phone":48,"phoneExt":10,"email":31},"507-266-7982",{"type":23,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Alex K. Bratt","Division Chair of Thoracic Radiology","100575267","multimodality-evaluation-of-left-ventricular-remodeling-in-mitral-regurgitation-a-pilot-study-100575267",false,"NCT06770062","Multimodality Evaluation of Left Ventricular Remodeling In Mitral Regurgitation: A Pilot Study","Inclusion Criteria:\n\n* Age \\>= 18\n* Male or Female\n* A diagnosis of severe chronic primary mitral regurgitation\n* Undergoing isolated robotic mitral annuloplasty at Mayo Clinic Rochester\n* Patients must have the ability to consent or have an appropriate representative available to do so.\n\nExclusion Criteria:\n\n* Prior valve intervention,\n* Concomitant valve surgery at the time of mitral annuloplasty (e.g. tricuspid annuloplasty, aortic valve replacement).\n* Concomitant \\>= moderate regurgitation or stenosis in any other valve by preoperative echocardiography\n* History of prior myocardial infarction\n* History of cardiomyopathy unrelated to mitral regurgitation (e.g. dilated, hypertrophic, infiltrative)\n* Pregnancy. Women of childbearing potential will be verbally screened by clinical staff during as part of routine pre-MRI evaluation. If a subject is unsure whether they could be pregnant, a negative pregnancy test will be performed prior to scanning.\n* Implantable devices that would be a contraindication to MRI\n* Severe allergy to gadolinium MRI contrast","ALL","18 Years",{"count":61,"type":62},30,"ESTIMATED","OBSERVATIONAL","The purpose of this research is to determine the feasibility of a larger, future study proposing a multimodal approach using cardiac CT and MRI to assess the risk of developing left ventricular (LV) systolic dysfunction in patients with mitral regurgitation (MR).",[66],"Left Ventricular Systolic Dysfunction","2026-02-27",{"date":69,"type":70},"2026-03-03","ACTUAL",{"date":72,"type":70},"2025-01-20",{"date":74,"type":62},"2027-12",{"name":5,"class":6},1]