[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100571851":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":10,"responsibleParty":26,"collaborators":10,"id":29,"slug":30,"hasResults":31,"nctId":32,"briefTitle":33,"officialTitle":33,"acronym":10,"eligibilityCriteria":34,"healthyVolunteers":31,"sex":35,"minAge":36,"maxAge":37,"enrollmentInfo":38,"targetDuration":41,"studyType":42,"phases":10,"briefSummary":43,"conditions":44,"keywords":10,"overallStatus":47,"whyStopped":10,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":55,"locationsCount":10},{"fullName":5,"class":6},"Zhejiang Chinese Medical University","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"LNM group and NLNM group",null,"The primary objective of this study is to evaluate the accuracy of the ThyMPR-CLNM model in predicting central lymph node metastasis (CLNM) in patients with stage T1 papillary thyroid carcinoma (PTC).",[13],"Diagnostic Test: Thy_CLNM_multi_omics",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Thy_CLNM_multi_omics","Surgery",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Tianhan Zhou","CONTACT","8615556960687","201911122511374@zcmu.edu.cn",{"type":27,"investigatorFullName":22,"investigatorTitle":28,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Clinical Professor","100571851","multiomics-study-of-biological-behavior-of-lymph-node-metastasis-in-papillary-thyroid-carcinoma-100571851",false,"NCT06725628","Multiomics Study of Biological Behavior of Lymph Node Metastasis in Papillary Thyroid Carcinoma","Inclusion Criteria:\n\n1. Pathological confirmation of PTC.\n2. Patients who underwent primary surgery accompanied by central neck lymph node dissection.\n3. Tumors measuring less than 2 cm in diameter.\n4. Postoperative pathological reports including detailed information on the number of lymph nodes dissected and the number of metastatic lymph nodes.\n5. Availability of comprehensive preoperative thyroid ultrasound images for analysis.\n\nExclusion Criteria:\n\n1. Postoperative pathological diagnosis indicating sub-types of PTC.\n2. Tumor invasion into adjacent anatomic structures such as the sternothyroid muscle, surrounding soft tissues, trachea, esophagus, or laryngeal nerve.\n3. History of neck trauma, previous tumor surgery, or adjuvant chemoradiotherapy.\n4. Fewer than three lymph nodes dissected during surgery.\n5. Concurrent acute inflammatory conditions or other hematologic disorders.","ALL","18 Years","80 Years",{"count":39,"type":40},2000,"ESTIMATED","5 Years","OBSERVATIONAL","Establish a predictive model for assessing neck lymph node metastasis of papillary thyroid carcinoma based on metabolomics, proteomics, and imaging omics data, exploring an ideal protocal for the precise diagnosis and treatment of papillary thyroid carcinoma.\"",[45,46],"Papillary Thyroid Carcinoma","Lymph Node Cancer Metastatic","NOT_YET_RECRUITING","2024-12-04",{"date":50,"type":51},"2024-12-10","ACTUAL",{"date":53,"type":40},"2024-12-01",{"date":53,"type":40},{"name":22,"class":6}]