[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100478503":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":19,"centralContacts":24,"locations":29,"responsibleParty":46,"collaborators":49,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":18,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":32,"whyStopped":18,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"University Hospital of Mont-Godinne","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"RRMS patients","RRMS patients initiating a new DMT",[12],"Other: Multiparametric assessment",[14],{"type":6,"name":15,"description":16,"armGroupLabels":17,"otherNames":18},"Multiparametric assessment","neuropsychological assessment, PRO measures, non-conventional MRI metrics",[9],null,[20],{"name":21,"affiliation":22,"role":23},"Frédéric London, MD","University Hospital Mont-Godinne","PRINCIPAL_INVESTIGATOR",[25],{"name":21,"role":26,"phone":27,"phoneExt":18,"email":28},"CONTACT","+3282413345","frederic.london@chuuclnamur.uclouvain.be",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":18,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"CHU UCL Namur site Godinne","RECRUITING","Yvoir","Namur","Belgium","BE",{"type":38,"coordinates":39},"Point",[40,41],4.88059,50.3279,{"lat":41,"lon":40},[44],{"name":21,"role":26,"phone":45,"phoneExt":18,"email":28},"+3281423345",{"type":23,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Frédéric London","Principal Investigator",[50],{"name":51,"class":52},"Saint-Luc University Hospital","UNKNOWN","100478503","multiparametric-assessment-to-investigate-prognostic-factors-for-disease-evolution-a-nd-evolutionary-patterns-of-cognitive-status-in-rrms-100478503",false,"NCT05510817","Multiparametric Assessment to Investigate Prognostic Factors for Disease Evolution a nd Evolutionary Patterns of Cognitive Status in RRMS","Multiparametric Clinical, Radiological, Neuropsychological, and Neurophysiological Assessment to Investigate Prognostic Factors for Disease Evolution and Treatment Response in MS: a Prospective Study.","COGNIT-MS","Inclusion Criteria:\n\n* active MS, according to the Lublin criteria\n* disease duration \\\u003C 10 years before initiating or changing a disease-modifying therapies,\n* relapse- and steroid-free for at least 1 month before MRI acquisition\n* between 18-50 years old\n* having given informed consent\n* with no significant comorbidity other than MS or substance abuse that could interfere with cognitive performances\n\nExclusion Criteria:\n\n* progressive forms of MS","ALL","18 Years","50 Years",{"count":65,"type":66},50,"ESTIMATED","INTERVENTIONAL",[69],"NA","This prospective study combining non conventional MRI techniques, neuropsychological screening tools, and a neurophysiological work-up using a sensitive and validated battery, will evaluate the predictive value of these measures and will explore the changes of the cognitive scores from baseline.",[72],"Multiple Sclerosis, Relapsing-Remitting",[74,75,76,77],"MRI","evoked potentials","cognitive function","PROMs","2023-12-03",{"date":80,"type":81},"2023-12-05","ACTUAL",{"date":83,"type":81},"2022-06-06",{"date":85,"type":66},"2026-06-06",{"name":5,"class":6},1]