[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100592879":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":30,"responsibleParty":50,"collaborators":10,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":10,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":10,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":33,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"University Hospital Muenster","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"HCC patients undergoing TACE or SIRT",null,"Patients with hepatocellular carcinoma scheduled for TACE or SIRT, undergoing multiparametric MRI at three defined time points.",[13],"Diagnostic Test: Multiparametric MRI",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Multiparametric MRI","Diagnostic multiparametric liver MRI, performed at three time points: before (≤14 days), 24 hours after, and 4-6 weeks after TACE or 3 months after SIRT.",[9],[21,26],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Max Masthoff, MD","CONTACT","+492518343018","max.masthoff@ukmuenster.de",{"name":27,"role":23,"phone":28,"phoneExt":10,"email":29},"Philipp Schindler, MD","+492518343015","philipp.schindler@ukmuenster.de",[31],{"facility":32,"status":33,"city":34,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Clinic of Radiology, University of Münster","RECRUITING","Münster","Germany","DE",{"type":38,"coordinates":39},"Point",[40,41],7.62571,51.96236,{"lat":41,"lon":40},[44,45,47,48],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},{"name":22,"role":46,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"name":27,"role":46,"phone":10,"phoneExt":10,"email":10},{"name":49,"role":46,"phone":10,"phoneExt":10,"email":10},"Emily Hoffmann, MD",{"type":46,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Emily Hoffmann","MD","100592879","multiparametric-mri-for-characterization-of-hepatocellular-carcinoma-100592879",false,"NCT06999174","Multiparametric MRI for Characterization of Hepatocellular Carcinoma","Multiparametric MRI for Optimized Imaging-based Characterization and Therapy Management of Hepatocellular Carcinoma","Inclusion Criteria:\n\n* Age ≥18 years\n* Confirmed or suspected diagnosis of HCC\n* Scheduled to receive TACE or SIRT as part of standard clinical care\n* Eligibility for liver MRI\n* Willing and able to provide written informed consent\n\nExclusion Criteria:\n\n* Contraindications to MRI (e.g., pacemakers, ferromagnetic implants, severe claustrophobia)\n* Known allergy or intolerance to gadolinium-based contrast agents\n* Renal insufficiency with estimated glomerular filtration rate (eGFR) \\\u003C30 mL\u002Fmin\u002F1.73m²\n* Pregnancy or breastfeeding\n* Inability to provide informed consent","ALL","18 Years",{"count":63,"type":64},128,"ESTIMATED","OBSERVATIONAL","This prospective observational study investigates using multiparametric magnetic resonance imaging (MRI) to improve the characterization and management of therapy for hepatocellular carcinoma (HCC). The goal is to evaluate whether advanced MRI parameters can support noninvasive diagnostic assessments and personalized treatment plans for patients with HCC. The study is being conducted at a single university center in Germany and includes adult patients with confirmed or suspected HCC. Participants will undergo standardized multiparametric MRI examinations, and the imaging data will be correlated with clinical, pathological, and therapeutic outcomes. No study-specific interventions or medications will be administered.",[68],"Hepatocellular Carcinoma (HCC)",[17,70,71],"TACE","SIRT","2025-06-28",{"date":74,"type":75},"2025-07-02","ACTUAL",{"date":77,"type":75},"2025-05-01",{"date":79,"type":64},"2028-05-01",{"name":5,"class":6},1]