[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622048":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":18,"locations":24,"responsibleParty":38,"collaborators":40,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":10,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Nantes University Hospital","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Age-matched Controls",null,"Age matched non-affected men, matched for men with Becker and Duchenne Muscular Dystrophies",{"label":13,"type":10,"description":14,"interventionNames":10},"Boys\u002FMen with Duchenne Muscular Dystrophy","This group will include ambulatory and non-ambulatory boys\u002Fmen with Duchenne Muscular Dystrophy ranging from 5-30 years old.",{"label":16,"type":10,"description":17,"interventionNames":10},"Boys\u002FMen with Becker Muscular Dystrophy","This group will include ambulatory and non-ambulatory men with Becker Muscular Dystrophy ranging from 5-60 years old.",[19],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Yann PEREON","CONTACT","0240083704","yann.pereon@chu-nantes.fr",[25],{"facility":26,"status":27,"city":28,"state":10,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":10},"CHU de Nantes","RECRUITING","Nantes","44093","France","FR",{"type":33,"coordinates":34},"Point",[35,36],-1.55336,47.21725,{"lat":36,"lon":35},{"type":39,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[41],{"name":42,"class":43},"AGENCE NATIONALE DE RECHERCHE","UNKNOWN","100622048","multiparametric-ultrafast-ultrasound-biomarkers-for-duchenne-and-becker-muscular-dystrophies-100622048",false,"NCT07378553","Multiparametric Ultrafast Ultrasound Biomarkers for Duchenne and Becker Muscular Dystrophies","Multiparametric Ultrafast Ultrasound Evaluation of Skeletal Muscle in Duchenne and Becker Muscular Dystrophies","INNOVAN","Inclusion Criteria:\n\n* Inclusion Criteria for patients with Duchenne Muscular Dystrophy: Ambulatory and non-ambulatory males (ages 5-30 at baseline testing) previously diagnosed with Duchenne Muscular Dystrophy based on absence of dystrophin expression.\n* Inclusion Criteria for patients with Becker Muscular Dystrophy: Ambulatory and non-ambulatory males (ages 5-60 at baseline testing) previously diagnosed with Becker Muscular Dystrophy based on genetically confirmed, reduced or dysfunctional dystrophin.\n* Inclusion Criteria for Aged-matched controls: Ambulatory males (ages 5-60 years) without disease or injury to the lower and\u002For upper extremities\n\nExclusion Criteria:\n\n* Exclusion Criteria for patients with Duchenne and Becker Muscular Dystrophies:\n\nInability to undergo static exam, missing measurement site (resection\u002Famputation), neurocognitive impairment preventing informed consent\n\n* Exclusion Criteria for Age-matched controls: Any condition affecting muscle metabolism\u002Ffunction, neuromuscular disease, or injury to the lower and\u002For upper extremities in the past 5 years",true,"MALE","5 Years","60 Years",{"count":57,"type":58},60,"ESTIMATED","OBSERVATIONAL","The purpose of this research study is to determine the potential of a multiparametric ultrasound approach to non-invasively monitor disease progression and to serve as an objective outcome measure for future clinical trials in Duchenne and Becker Muscular Dystrophies.\n\nThe investigators will compare the muscles of ambulatory or non-ambulatory boys\u002Fmen with Duchenne and Becker Dystrophies with muscles of healthy age-matched individuals of the same age and monitor disease progression in those with muscular dystrophies over a 12-month year period.\n\nThe ultrafast ultrasound technology used in this study allows the simultaneous assessment of muscle structure, mechanics and physiology, including stiffness, anisotropy, viscosity, intramuscular fat, muscle volume, and microvascular perfusion. The amount of muscle alteration measured will be related to performance in daily activities, such as walking and muscle strength, in order to identify sensitive and objective markers of disease progression.",[62,63],"Duchene Muscular Dystrophy","Becker Muscular Dystrophy",[65,63,66,67,68],"Duchenne Muscular Dystrophy","Ultrasound Imaging","Ultrafast Ultrasound","Muscle","2026-06-23",{"date":71,"type":72},"2026-06-24","ACTUAL",{"date":74,"type":72},"2026-03-03",{"date":76,"type":58},"2029-03-03",{"name":5,"class":6},1]