[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100493567":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":27,"centralContacts":28,"locations":34,"responsibleParty":51,"collaborators":54,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":27,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":27,"enrollmentInfo":68,"targetDuration":27,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":37,"whyStopped":27,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Istituti Clinici Scientifici Maugeri SpA","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1","EXPERIMENTAL","Group 1 will receive tEs combined with music stimulation for 2 weeks, 1 week of wash out, then sham stimulation combined with noise (placebo) for other 2 weeks.",[13],"Other: Combinatory effect of music stimulation and neurostimulation",{"label":15,"type":10,"description":16,"interventionNames":17},"Group 2","Group 2 will receive sham stimulation and noise (placebo) for the first 2 weeks, then 1 week wash out, and finally tEs and music stimulation for other 2 weeks.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Group 3","Group 3 will receive only music stimulation and sham stimulation for 2 weeks, 1 week of wash out, then sham stimulation and noise (placebo) for another 2 weeks.",[13],[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"Combinatory effect of music stimulation and neurostimulation","music",[9,15,19],null,[29],{"name":30,"role":31,"phone":32,"phoneExt":27,"email":33},"Simona Spaccavento","CONTACT","+393332783524","simona.spaccavento@icsmaugeri.it",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Istituti Clinici Scientifici Maugeri","RECRUITING","Bari","Ba","70025","Italy","IT",{"type":44,"coordinates":45},"Point",[46,47],16.86982,41.12066,{"lat":47,"lon":46},[50],{"name":30,"role":31,"phone":27,"phoneExt":27,"email":27},{"type":52,"investigatorFullName":30,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":27,"oldOrganization":27},"PRINCIPAL_INVESTIGATOR","Principal Investigator",[55,57],{"name":56,"class":6},"University of Bari Aldo Moro",{"name":58,"class":6},"University of Aarhus","100493567","music-intervention-and-transcranial-electrical-stimulation-for-neurological-diseases-100493567",false,"NCT05706831","Music Intervention and Transcranial Electrical Stimulation for Neurological Diseases","Music Intervention and Transcranial Electrical Stimulation for Treating Neurological Diseases","Inclusion Criteria:\n\n* Age \\> 18 years\n* Post-stroke aphasia\n* Post-stroke neglect\n* Patients with disorders of consciusness (DOC)\n\nExclusion Criteria:\n\n* No auditory injury\n* no hystory of neurological disease\n* No hystory of psychiatric disease\n* Previous stroke\n* use of alcohol and drugs\n* premorbid dementia","ALL","18 Years",{"count":69,"type":70},90,"ESTIMATED","INTERVENTIONAL",[73],"NA","The goal of this clinical trial is to evaluate the efficacy of a musical interventionand non-invasive brain stimulation in neurological patients. The main questions it aims to answer are:\n\n* to evaluate the residual neuroplastic processes in DOC state related to music exposure\n* to determine the putative modulation of the aforementioned processes and the clinical outcome of DOC patients by non-pharmacological strategies, i.e., electric (tDCS) and music stimulation\n* to evaluate the impact of this intervention on caregiver's burden and psychological distress.\n\nParticipants will be randomly assigned to one of three different music-listening intervention groups. Primary outcomes will be clinical, that is based on the neurologist's observations of clinical improvement, and neurophysiological, collected pre-intervention, post-intervention and post-placebo.",[76,77],"Disorder of Consciousness","Stroke",[79,80,81,82,83,77],"music stimulation","tDCS","Aphasia","Neglect","DOC","2025-05-30",{"date":86,"type":87},"2025-06-04","ACTUAL",{"date":89,"type":87},"2022-09-01",{"date":91,"type":70},"2026-12-31",{"name":5,"class":6},1]