[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573350":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":31,"responsibleParty":49,"collaborators":18,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":18,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":18,"enrollmentInfo":62,"targetDuration":18,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":18,"overallStatus":34,"whyStopped":18,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Shanghai 10th People's Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Periodontal Health Intervention Group","EXPERIMENTAL","Participants in this arm will receive comprehensive periodontal health interventions, including:\n\n1. Full periodontal evaluation using dental mirrors and probes (assessing visible plaque, probing depth, bleeding on probing, and attachment loss).\n2. Supragingival scaling, root planing, and professional plaque removal.\n3. Temporary restoration of carious lesions and extraction of root remnants, as needed.\n4. Personalized oral hygiene instruction, including the use of multi-tufted brushes, toothpaste, floss, and interdental brushes.",[13],"Procedure: Periodontal surgery",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Care Group","NO_INTERVENTION","Participants in this arm will receive standard care without specific periodontal interventions. This includes routine medical management for myocardial infarction, as per standard clinical guidelines, without structured periodontal treatment.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"PROCEDURE","Periodontal surgery","In the intervention group, patients underwent a comprehensive periodontal evaluation conducted by periodontists at a dental clinic. All permanent teeth, except for third molars, were assessed using dental mirrors and periodontal probes. Each tooth was examined at four sites (vestibular, distal, lingual, and mesial) to evaluate visible plaque, probing depth, probing bleeding, and attachment loss.\n\nDuring the first treatment session, patients were provided with information about periodontal disease, emphasizing the importance of controlling supragingival bacterial biofilms for successful treatment. Plaque-retentive factors (calculus) were removed. Temporary materials were used to restore carious lesions, root remnants were extracted, and maladaptive restorations were adjusted. Supragingival calculus was removed using periodontal scalers, followed by cleaning with a rubber cup, prophylaxis paste, dental floss, and\u002For interdental brushes. No prophylactic antibiotics were used prior to the",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Jiawen Wu","CONTACT","86+17717070557","chloewuu@foxmail.com",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Shanghai Tenth People's Hospital","RECRUITING","Shanghai","Shanghai Municipality","200092","China","CN",{"type":41,"coordinates":42},"Point",[43,44],121.45806,31.22222,{"lat":44,"lon":43},[47],{"name":27,"role":28,"phone":48,"phoneExt":18,"email":30},"17717070557",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Ya-Wei Xu","professor of medicine","100573350","myocardial-infarction-and-periodontitis-periodontal-health-intervention-100573350",false,"NCT06745141","Myocardial Infarction and Periodontitis: Periodontal Health Intervention.","Oral Health Intervention Study in Patients with Myocardial Infarction and Periodontal Disease: a Simulated RCT Trial","Inclusion Criteria:\n\n* 1)Patients diagnosed with ST-segment elevation myocardial infarction (STEMI). 2)Patients with severe periodontal disease, defined as:\n\n  * 5 teeth with clinical attachment loss (CAL) ≥ 4 mm.\n\n    * Subgingival probing depth (PD) ≥ 6 mm. ③≥ 8 teeth with gingival bleeding on probing (BOP). 3）Age ≥30 years. 4）Written informed consent provided.\n\nExclusion Criteria:\n\n* 1\\) under 30 years old; 2) HIV positive, chronic inflammation, tumor disease, drug dependence, use of anticonvulsants, use of immunosuppressive agents, pregnancy, and lactation; 3) significant tooth loss (number of remaining teeth \\\u003C 8); 4) long hospital stay (\\>10 days), new myocardial infarction before randomization, and stent thrombosis; 5) Refusal to sign informed consent.","ALL","30 Years",{"count":63,"type":64},100,"ESTIMATED","INTERVENTIONAL",[67],"NA","The aim of this study is to establish a shared database of acute myocardial infarction patients with periodontitis, to clarify the clinical benefits of periodontitis intervention on acute myocardial infarction patients through simulated RCT study, and to establish a high-level database of acute myocardial infarction patients with periodontitis, so as to promote the application of oral health intervention in clinical practice.",[70,71],"Acute Myocardial Infarction (AMI)","Periodontal Disease","2024-12-17",{"date":74,"type":75},"2024-12-20","ACTUAL",{"date":77,"type":75},"2020-12-01",{"date":79,"type":64},"2025-12-31",{"name":5,"class":6},1]