[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633021":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":37,"locations":46,"responsibleParty":68,"collaborators":26,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":26,"eligibilityCriteria":77,"healthyVolunteers":73,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":26,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":26,"overallStatus":49,"whyStopped":26,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Al-Azhar University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"silver-hydroxyapatite nanocoated titanium miniscrews","EXPERIMENTAL","Patients will receive silver-hydroxyapatite nanocoated titanium miniscrews. These miniscrews will be placed in the maxillary bone for en masse retraction of the upper anterior teeth.",[13],"Device: Silver nanoparticles",{"label":15,"type":16,"description":17,"interventionNames":18},"uncoated titanium miniscrews","ACTIVE_COMPARATOR","Patients will receive conventional uncoated titanium miniscrews of the same dimensions and design as Arm 1, but without nano-coating.",[19],"Device: uncoated titanium miniscrews",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Silver nanoparticles","Patients will receive silver-hydroxyapatite nanocoated titanium miniscrews.These miniscrews will be placed in the maxillary bone for en masse retractonof the upper anterior teeth.",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"Patients will receive conventional uncoated titanium miniscrews of the same dimensions and design as the intervention of the group1, but without nano-coating.",[15],[31,35],{"name":32,"affiliation":33,"role":34},"Mahmoud FA Aboelmahasen, Phd","Faculty of Dental Medicine (Boys), Al-Azhar University, Cairo, Egypt","STUDY_DIRECTOR",{"name":36,"affiliation":33,"role":34},"Ahmed Ak El-Awady, Phd",[38,43],{"name":39,"role":40,"phone":41,"phoneExt":26,"email":42},"Hashem Kh Al-Washali, MScCandidate","CONTACT","+01120042296","Hashemalwashali.2.209@azhar.edu.eg",{"name":32,"role":40,"phone":44,"phoneExt":26,"email":45},"+01222993318","MahmoudFathy.209@azhar.edu.eg",[47],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Faculty of Dental Medicine (Boys), Al-Azhar University","RECRUITING","Cairo","Cairo Governorate","4434103","Egypt","EG",{"type":56,"coordinates":57},"Point",[58,59],31.24967,30.06263,{"lat":59,"lon":58},[62,63,66],{"name":39,"role":40,"phone":41,"phoneExt":26,"email":42},{"name":64,"role":40,"phone":65,"phoneExt":26,"email":45},"Mahmoud Fa Aboelmahasen, Phd","+01222993381",{"name":39,"role":67,"phone":26,"phoneExt":26,"email":26},"PRINCIPAL_INVESTIGATOR",{"type":67,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Hashem Khalil Saleh Mohammed","Principle Investigator, MSc Candidate in Orthodontics","100633021","nano-coated-orthodontic-miniscrews-for-en-mass-retraction-of-the-upper-arch-100633021",false,"NCT07521267","Nano Coated Orthodontic Miniscrews for en Mass Retraction of the Upper Arch","Evaluation of Silver-Hydroxyapatite Nano-coated Versus Uncoated Orthodontic Miniscrews for en Masse Retraction of the Upper Anterior Segment: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Class I orthodontic cases with bimaxillary protrusion of the anterior segment of the upper jaw that need at least extraction for orthodontic treatment.\n* Age 14-20 years.\n* Good oral hygiene with healthy periodontium.\n* Need for an absolute skeletal anchorage.\n* Systemically healthy patients.\n\nExclusion Criteria:\n\n* Patient with craniofacial anomalies (e.g, cleft lip and palate)\n* Presence of systemic diseases or syndromes affecting bone metabolism (e.g, osteoporosis, rickets)\n* Poor oral hygiene or uncooperative patients.\n* Extensive dental caries or untreated periodontal disease.\n* History of trauma or surgery affecting the maxilla or mandible.","ALL","14 Years","20 Years",{"count":82,"type":83},14,"ESTIMATED","INTERVENTIONAL",[86],"NA","study will be directed to evaluate silver-hydroxyapatite nano-coated versus uncoated orthodontic miniscrews for en masse retraction of the upper anterior segment.",[89,90,91],"Class I Malocclusion","Maxillary Prognathism","Orthodontic Tooth Movement","2026-04-08",{"date":94,"type":95},"2026-04-13","ACTUAL",{"date":97,"type":83},"2026-05",{"date":99,"type":83},"2029-11",{"name":5,"class":6},1]