[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100509968":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":20,"centralContacts":25,"locations":36,"responsibleParty":55,"collaborators":30,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":30,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":30,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":30,"overallStatus":39,"whyStopped":30,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Ohio State University","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Single Arm","A device-nasal plug will be self-inserted into the nose with a diagonal channel embedded to redirect nasal airflow patterns to different nasal regions. A nose clip will be used to pinch the nose externally, similar to what synchronized swimmers use.",[12],"Other: Nasal Plug",[14],{"type":6,"name":15,"description":16,"armGroupLabels":17,"otherNames":18},"Nasal Plug","Please see the arm description for details.",[9],[19],"Swimmer's nose clip",[21],{"name":22,"affiliation":23,"role":24},"Kai Zhao, Ph.D","Associate Professor","PRINCIPAL_INVESTIGATOR",[26,32],{"name":27,"role":28,"phone":29,"phoneExt":30,"email":31},"Veronica Formanek, BS","CONTACT","630-501-8168",null,"Veronica.Formanek@osumc.edu",{"name":33,"role":28,"phone":34,"phoneExt":30,"email":35},"Beth Miles-Markley, MS","614-366-9244","Beth.Miles-Markley@osumc.edu",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Eye and Ear Institute, 915 Olentangy River Road, ENT, Suite 4000","RECRUITING","Columbus","Ohio","43212","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-82.99879,39.96118,{"lat":49,"lon":48},[52,53,54],{"name":27,"role":28,"phone":29,"phoneExt":30,"email":31},{"name":33,"role":28,"phone":34,"phoneExt":30,"email":35},{"name":22,"role":24,"phone":30,"phoneExt":30,"email":30},{"type":24,"investigatorFullName":56,"investigatorTitle":23,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Kai Zhao","100509968","nasal-obstruction-and-olfactory-losses-100509968",false,"NCT05920330","Nasal Obstruction and Olfactory Losses","Novel Mechanisms and Therapeutic Approaches for Nasal Obstruction and Olfactory Losses","Inclusion Criteria:\n\n1. Smell Loss complaints\n2. Nasal Obstruction\n\nExclusion Criteria:\n\n1. Congenital olfactory losses\n2. Nasal polyps, blocking the olfactory cleft\n3. Significant atrophy\n4. Cystic fibrosis\n5. Wegeners or any other connective tissue disorder\n6. Head trauma",true,"ALL","18 Years","70 Years",{"count":69,"type":70},330,"ESTIMATED","INTERVENTIONAL",[73],"NA","About 13% of US adults, some 30 million people, suffer from nasal sinus disease. Although nasal obstruction and smell loss are two of the major symptoms of the disease that are crucial to disease management, currently there is a lack of clinical tools to effectively evaluate the mechanisms contributing to these symptoms. The proposed study aims to develop novel clinical tools to better evaluate and relieve patients' nasal obstructive symptoms and to enable patients and clinicians to make more informed, personalized decisions regarding treatment strategy.",[76],"Nasal Obstruction","2026-05-21",{"date":79,"type":80},"2026-05-26","ACTUAL",{"date":82,"type":80},"2023-01-25",{"date":84,"type":70},"2028-12-31",{"name":5,"class":6},1]