[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100253471":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":17,"locations":26,"responsibleParty":133,"collaborators":136,"id":139,"slug":140,"hasResults":141,"nctId":142,"briefTitle":143,"officialTitle":143,"acronym":144,"eligibilityCriteria":145,"healthyVolunteers":141,"sex":146,"minAge":147,"maxAge":148,"enrollmentInfo":149,"targetDuration":152,"studyType":153,"phases":10,"briefSummary":154,"conditions":155,"keywords":159,"overallStatus":164,"whyStopped":10,"lastUpdateSubmitDate":165,"lastUpdatePostDateStruct":166,"startDateStruct":169,"completionDateStruct":171,"leadSponsor":173,"locationsCount":174},{"fullName":5,"class":6},"Semmelweis University Heart and Vascular Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Coronary CT Angiography (CCTA)",null,"Patients included in the OPeRA Registry are those that have previously undergone 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Maurovich-Horvat","Assistant Professor",[137],{"name":138,"class":6},"Hungarian Academy of Sciences","100253471","national-plaque-registry-and-database-100253471",false,"NCT02578355","National Plaque Registry and Database","OPeRA","Inclusion Criteria:\n\n* Age \\> 18 years\n* Subject providing written informed consent\n* Scheduled to undergo a clinically indicated coronary CTA\n\nExclusion Criteria:\n\n* Age \\\u003C18 years\n* Suspicion of acute coronary syndrome (acute myocardial infarction and unstable angina)\n* Recent prior myocardial infarction within 30 days prior to coronary CTA or between coronary CTA and ICA\n* Pregnancy or unknown pregnancy status in subject of childbearing potential\n* Subject requires an emergent procedure\n* Evidence of ongoing or active clinical instability, including acute chest pain (sudden onset), cardiogenic shock, unstable blood pressure with systolic blood pressure \\\u003C90 mmHg, and severe congestive heart failure (NYHA III or IV) or acute pulmonary edema\n* Inability to comply with study procedures","ALL","18 Years","90 Years",{"count":150,"type":151},20000,"ESTIMATED","5 Years","OBSERVATIONAL","The ultimate goal of this project is to develop a risk score to identify patients with vulnerable coronary atherosclerotic plaques, who are prone to suffer acute coronary syndrome. Early identification of vulnerable plaques may have an enormous impact on public health through primary and secondary prevention of acute myocardial infarction.\n\nInvestigators hypothesize that a risk score that incorporates non-invasive coronary CT imaging (calcium score and\u002For coronary CTA) in combination with clinical characteristics (classical risk prediction models) will improve the identification of patients who are at highest risk to suffer myocardial infarction or sudden cardiac death.\n\nThe overall goal of the OPeRA project is to develop, implement and validate a novel risk assessment tool based on image markers and clinical characteristics to identify patients who are at increased risk to suffer myocardial infarction or sudden cardiac death.",[156,157,158],"Atherosclerosis","Coronary Artery Disease","Cardiovascular Disease",[156,157,158,160,161,162,163,144],"Coronary Computed Tomographic Angiography","CCTA","Myocardial Infarction","MI","NOT_YET_RECRUITING","2017-04-24",{"date":167,"type":168},"2017-04-25","ACTUAL",{"date":170,"type":10},"2016-09",{"date":172,"type":151},"2030-12",{"name":5,"class":6},11]