[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100363892":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":31,"responsibleParty":47,"collaborators":10,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":51,"sex":57,"minAge":10,"maxAge":10,"enrollmentInfo":58,"targetDuration":10,"studyType":61,"phases":10,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"University Hospital, Lille","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Eosinophilia\u002FHypereosinophilic syndrome",null,"patient with eosinophilia and\u002For hypereosinophilic syndrome",[13],"Biological: Biological sample",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"BIOLOGICAL","Biological sample","Additional blood samples for biobanking",[9],[21],{"name":22,"affiliation":5,"role":23},"Guillaume Lefevre","PRINCIPAL_INVESTIGATOR",[25],{"name":26,"role":27,"phone":28,"phoneExt":29,"email":30},"Guillaume Lefevre, MD","CONTACT","03 20 44 55 72","+33","Guillaume.lefevre@chru-lille.fr",[32],{"facility":33,"status":34,"city":35,"state":10,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Hôpital Roger Salengro, CHU","RECRUITING","Lille","France","FR",{"type":39,"coordinates":40},"Point",[41,42],3.05512,50.63391,{"lat":42,"lon":41},[45],{"name":46,"role":23,"phone":10,"phoneExt":10,"email":10},"Guillaume Lefevre, MD,PhD",{"type":48,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100363892","natural-history-of-hypereosinophilia-and-hypereosinophilic-syndromes-100363892",false,"NCT04018118","Natural History of Hypereosinophilia and Hypereosinophilic Syndromes","Study of Clinical Profiles of Patients Followed for Chronic Hypereosinophilia and\u002For Hypereosinophilic Syndrome by the Creation of a National Cohort","COHESION","Inclusion Criteria:\n\n* Men or Women of any age :\n* With the diagnosis criteria of hyperosinophlia OR hypereosinophilic syndrome OR specific organ eosinophilic disease according to the consensus conference of the International Cooperative Working Group on Eosinophil Disorders (ICOG-EO)\n* With an AEC \\> 1500\u002Fmm3 or organ damage related to the presence of eosinophils in the tissues or organs whatever the context (idiopathic, clonal or reactive, including drug-related, parasitic or allergic)\n* HES diagnosis since 2005\u002F01\u002F01\n* Patients socially insured\n* Patient who agreed to participate to the study, its proceedings and duration.\n\nExclusion Criteria:\n\n* Known HIV infection\n* Not socially insured\n* Person unable to receive a enlighten information\n* Person who refuse to sign the consent\n* Persons deprived of their liberty\n* Persons benefiting from a system of legal protection (tutelage \u002F guardianship)","ALL",{"count":59,"type":60},600,"ESTIMATED","OBSERVATIONAL","Unexplained chronic hypereosinophilia (HE) and hypereosinophilic syndromes (HES) are heterogeneous regarding the organ involvements (heart, lungs, skin, .. or none), the evolutionary profiles, the response to treatments.\n\nUnderlying mechanisms are largely unknown and may associate genetic predisposing factors (germinal ? somatic?), environmental factors (alimentation, tobacco use, hormones, infections, ..) The COHESion study aims to study all clinical and biological characteristics of HE\u002FHES patients and their evolutionary profiles, with a focus on genetic factors and the mechanisms supporting transitory or persistant chronic HE\u002FHES (in absence of any well identified extrinsic trigger like drugs, parasitosis, ..)",[64,65],"Eosinophilia","Hypereosinophilic Syndrome",[64,67,65],"Hypereosinophilia","2026-02-18",{"date":70,"type":71},"2026-02-20","ACTUAL",{"date":73,"type":71},"2019-05-06",{"date":75,"type":60},"2031-05",{"name":5,"class":6},1]