[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100496024":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":29,"responsibleParty":50,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"National Institutes of Health Clinical Center (CC)","NIH",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Healthy Volunteers",null,"18 years old and up",{"label":13,"type":10,"description":14,"interventionNames":10},"Patients","greater than 2 years old",[16],{"name":17,"affiliation":18,"role":19},"Andrew L Mammen, M.D.","National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)","PRINCIPAL_INVESTIGATOR",[21,26],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Julie G Thompson, R.N.","CONTACT","(301) 480-3191","julie.thompson@nih.gov",{"name":17,"role":23,"phone":27,"phoneExt":10,"email":28},"(301) 594-6667","andrew.mammen@nih.gov",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"National Institutes of Health Clinical Center","RECRUITING","Bethesda","Maryland","20892","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-77.10026,38.98067,{"lat":42,"lon":41},[45],{"name":46,"role":23,"phone":47,"phoneExt":48,"email":49},"NIH Clinical Center Office of Patient Recruitment (OPR)","800-411-1222","TTY dial 711","ccopr@nih.gov",{"type":51,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100496024","natural-history-of-inflammatory-muscle-diseases-100496024",false,"NCT05738824","Natural History of Inflammatory Muscle Diseases","* INCLUSION CRITERIA:\n\nIn order to be eligible to participate in this study, an individual must meet all of the following criteria:\n\n1\\. Ability of subject, or Legally Authorized Representative (LAR) to understand and the willingness to sign a written informed consent and\u002For assent document.\n\n2a. Patients are adults and minors of age 2 or older, with possible inflammatory myopathy (suspected or confirmed)\n\nOR\n\n2b. Healthy volunteers will be adults aged 18 or older.\n\nEXCLUSION CRITERIA:\n\n1\\. Unwilling to participate in research studies or to provide research samples or data.",true,"ALL","2 Years","120 Years",{"count":63,"type":64},500,"ESTIMATED","OBSERVATIONAL","Objective:\n\nTo collect information and biospecimens (such as blood, muscle, and skin samples) that will be used to research causes and treatments of inflammatory muscle diseases.\n\nEligibility:\n\nPeople aged 2 years and older with suspected or confirmed inflammatory muscle disease. Healthy volunteers aged 18 years and older are also needed.\n\nDesign:\n\nParticipants will have at least 1 clinic visit. Each visit will last 4 to 8 hours. Some may return for additional visits.\n\nAll participants will undergo these procedures (unless they are unable to):\n\n* Physical exam, including blood and urine tests.\n* Magnetic resonance imaging (MRI) scan of the thigh. Participants will lie still on a table with padding around 1 thigh. The table will slide into a tube. The scan will last for approximately 40 minutes.\n\nSome procedures are optional:\n\n* Muscle biopsy: An area of skin will be numbed. A quarter-inch cut will be made. Several pieces of muscle tissue, about the size of grains of rice, will be removed.\n* Skin biopsy: An area of skin will be numbed. A piece of skin about a quarter inch in diameter will be removed.\n* Lymph node biopsy: A small sample of fluid or tissue from a lymph node will taken to check for infection.\n* Genetic testing. Some of the samples collected may be used for genetic testing.",[68],"Inflammation In Skeletal Muscle",[70,71,72,73],"Polymyositis","Dermatomyositis","Childhood Dermatomyositis","Natural History","2026-06-25",{"date":76,"type":77},"2026-06-26","ACTUAL",{"date":79,"type":77},"2023-06-01",{"date":81,"type":64},"2032-02-25",{"name":18,"class":6},1]