[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100443407":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":35,"locations":45,"responsibleParty":128,"collaborators":131,"id":138,"slug":139,"hasResults":140,"nctId":141,"briefTitle":142,"officialTitle":143,"acronym":18,"eligibilityCriteria":144,"healthyVolunteers":140,"sex":145,"minAge":146,"maxAge":18,"enrollmentInfo":147,"targetDuration":18,"studyType":150,"phases":151,"briefSummary":153,"conditions":154,"keywords":18,"overallStatus":48,"whyStopped":18,"lastUpdateSubmitDate":156,"lastUpdatePostDateStruct":157,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":165},{"fullName":5,"class":6},"Zealand University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"NAVIGATE intervention arm","EXPERIMENTAL","Nurse navigation",[13],"Behavioral: NAVIGATE",{"label":15,"type":16,"description":17,"interventionNames":18},"Navigate control arm","NO_INTERVENTION","Standard treatment and care",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","NAVIGATE","Patients' symptoms are systematically monitored by use of bi-weekly patient reported outcomes and nurse navigators will initiate appropriate actions in terms of medical treatment or guidance of self-management strategies. Nurse navigators will motivate and support patients in health behavior changes and in selfmanaging their treatment and symptoms, and, if relevant, refer to existing rehabilitation services at the hospital or at the local rehabilitation center. Physiotherapists will supervise a training program aimed at improving patients' physical function and thus potentially surgery and overall treatment adherence and outcomes.",[9],[26,29,32],{"name":27,"affiliation":5,"role":28},"Susanne O Dalton, Professor","PRINCIPAL_INVESTIGATOR",{"name":30,"affiliation":31,"role":28},"Pernille E Bidstrup, PhD","Danish Cancer Society",{"name":33,"affiliation":34,"role":28},"Erik Jakobsen, PhD","The Danish Lung Cancer Research Center",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":18,"email":40},"Rikke Langballe, PhD","CONTACT","+45 35 25 79 72","ril@cancer.dk",{"name":42,"role":38,"phone":43,"phoneExt":18,"email":44},"Randi V Karlsen, MEd","+45 35 25 76 65","randi@cancer.dk",[46,62,74,89,100,113],{"facility":47,"status":48,"city":49,"state":18,"zip":18,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Aalborg University Hospital","RECRUITING","Aalborg","Denmark","DK",{"type":53,"coordinates":54},"Point",[55,56],9.9187,57.048,{"lat":56,"lon":55},[59],{"name":60,"role":38,"phone":18,"phoneExt":18,"email":61},"Tine Krogh Mcculloch","tine.mcculloch@rn.dk",{"facility":63,"status":48,"city":64,"state":18,"zip":18,"country":50,"countryCode":51,"cosmosGeoPoint":65,"geoPoint":69,"contacts":70},"Gødstrup Hospital","Herning",{"type":53,"coordinates":66},[67,68],8.97662,56.13615,{"lat":68,"lon":67},[71],{"name":72,"role":38,"phone":18,"phoneExt":18,"email":73},"Hanne Linnet","hansin@rm.dk",{"facility":75,"status":48,"city":76,"state":18,"zip":18,"country":50,"countryCode":51,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"Odense University Hospital","Odense",{"type":53,"coordinates":78},[79,80],10.38831,55.39594,{"lat":80,"lon":79},[83,86],{"name":84,"role":38,"phone":18,"phoneExt":18,"email":85},"Christian Borbjerg Laursen","Christian.B.Laursen@rsyd.dk",{"name":87,"role":38,"phone":18,"phoneExt":18,"email":88},"Line Larsen","Line.Larsen2@rsyd.dk",{"facility":5,"status":48,"city":90,"state":18,"zip":18,"country":50,"countryCode":51,"cosmosGeoPoint":91,"geoPoint":95,"contacts":96},"Roskilde",{"type":53,"coordinates":92},[93,94],12.08035,55.64152,{"lat":94,"lon":93},[97],{"name":98,"role":38,"phone":18,"phoneExt":18,"email":99},"Mads Nordahl Svendsen","mnsv@regionsjaelland.dk",{"facility":101,"status":48,"city":102,"state":18,"zip":18,"country":50,"countryCode":51,"cosmosGeoPoint":103,"geoPoint":107,"contacts":108},"Sønderborg Sygehus","Sønderborg",{"type":53,"coordinates":104},[105,106],9.78917,54.90896,{"lat":106,"lon":105},[109,111],{"name":110,"role":38,"phone":18,"phoneExt":18,"email":18},"Kim Wedervang",{"name":18,"role":38,"phone":18,"phoneExt":18,"email":112},"Kim.Wedervang@rsyd.dk",{"facility":114,"status":48,"city":115,"state":18,"zip":18,"country":50,"countryCode":51,"cosmosGeoPoint":116,"geoPoint":120,"contacts":121},"Vejle Sygehus","Vejle",{"type":53,"coordinates":117},[118,119],9.5357,55.70927,{"lat":119,"lon":118},[122,125],{"name":123,"role":38,"phone":18,"phoneExt":18,"email":124},"Ole Hilberg","Ole.Hilberg@rsyd.dk",{"name":126,"role":38,"phone":18,"phoneExt":18,"email":127},"Kirsten Jones","Kirsten.Jones@rsyd.dk",{"type":28,"investigatorFullName":129,"investigatorTitle":130,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Susanne Dalton","Professor, MD, PhD",[132,133,134,136],{"name":31,"class":6},{"name":75,"class":6},{"name":135,"class":6},"Vejle Hospital",{"name":137,"class":6},"Hospital of Southern Jutland","100443407","navigate---improving-survival-and-quality-of-life-in-vulnerable-lung-cancer-patients-100443407",false,"NCT05053997","Navigate - Improving Survival and Quality of Life in Vulnerable Lung Cancer Patients","NAVIGATE - Improving Survival and Quality of Life in Vulnerable Lung Cancer Patients Through Nurse Navigation, Symptom Monitoring and Exercise: Study Protocol for a Multicenter Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥ 18 years of age\n* Diagnosed with NSCLC at all stages regardless of treatment intension at the participating departments\n* Performance status ≤ 2\n* Vulnerable according to pre-defined criteria\n\nExclusion Criteria:\n\n* Severe untreated psychiatric disorder (e.g. psychosis) or cognitive problems (e.g. dementia) preventing informed consent\n* Not able to receive treatment\n* Not able to read and understand Danish -","ALL","18 Years",{"count":148,"type":149},250,"ESTIMATED","INTERVENTIONAL",[152],"NA","Half of patients with lung cancer face a limited life span of one-year survival, which is characterized by severe physical and psychological symptoms. Differences in stage, comorbidity but also treatment may explain a large proportion of the social inequality in lung cancer survival. Some vulnerable patients may not receive first line treatment as planned either due to poor performance status or if they are not able to adhere to treatment appointments. Knowing how to navigate the health system may be a barrier preventing vulnerable patients in receiving optimal treatment. The primary aim of this randomised, controlled trial is to test whether a nurse-led individually tailored program including systematic screening of symptoms using PROs and a physical training program will significantly improve a composite outcome of survival and quality of life as the primary outcome among vulnerable lung cancer patients compared with standard care. Secondary outcomes include adherence to cancer treatment, symptom burden and overall survival.",[155],"Lung Cancer","2025-12-20",{"date":158,"type":159},"2025-12-29","ACTUAL",{"date":161,"type":159},"2022-03-01",{"date":163,"type":149},"2026-12-31",{"name":5,"class":6},6]