[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626412":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":24,"locations":25,"responsibleParty":43,"collaborators":45,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":24,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":24,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":24,"overallStatus":28,"whyStopped":24,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"National University Hospital, Singapore","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"real-sham","EXPERIMENTAL","Subjects will receive 10 sessions of real nTMS, 5 times a week for 2 weeks, followed by 10 sessions of sham nTMS, 5 times a week for 2 weeks. There will be a 2-week break between the 2 types of nTMS.",[13],"Device: navigated rTMS",{"label":15,"type":10,"description":16,"interventionNames":17},"sham-real","Subjects will receive 10 sessions of sham nTMS, 5 times a week for 2 weeks, followed by 10 sessions of real nTMS, 5 times a week for 2 weeks. There will be a 2-week break between the 2 types of nTMS.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","navigated rTMS","Each session of rTMS (real or sham) consists of 1200 stimulations\u002Fday, conducted at once a day for five consecutive days (from Monday to Friday).\n\nFor sham stimulation, the TMS coil will still centre on the same scalp position, but it was tilted to 90° so that scalp contact and discharging noise were similar, but the magnetic field did not reach cortical neurons at a biologically active level.\n\nThe localization of the rTMS stimulation site (left Temporal Cortex) will be directed by a neuronavigation system imported with subject's MRI scan imaging to ensure the accuracy of rTMS stimulation area.",[9,15],null,[26],{"facility":27,"status":28,"city":29,"state":24,"zip":24,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Alexandra Hospital","RECRUITING","Singapore","SG",{"type":32,"coordinates":33},"Point",[34,35],103.85007,1.28967,{"lat":35,"lon":34},[38],{"name":39,"role":40,"phone":41,"phoneExt":24,"email":42},"Nicodemus Edrick Oey, MBBS, PhD","CONTACT","8798 5734","nicodemus_edrick_oey@nuhs.edu.sg",{"type":44,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR",[46],{"name":27,"class":6},"100626412","navigated-repetitive-tms-for-chronic-tinnitus-100626412",false,"NCT07435298","Navigated Repetitive TMS for Chronic Tinnitus","Neuronavigated Transcranial Magnetic Stimulation As An Adjunctive Treatment For Chronic Tinnitus","Inclusion Criteria:\n\n1. Age 21-80 years old;\n2. Subjective tinnitus severity as per Tinnitus-Visual Analogue Scale of 1\u002F10 and above (in any domain: sound, distress, Quality of Life)\n\nExclusion Criteria:\n\n1. Pregnancy;\n2. Any metal implants inside the body that are contraindications of MRI scan;\n3. Cardiac pacemakers;\n4. Epilepsy with recurrent seizures;\n5. Cognitively impaired patients will be excluded;\n6. Claustrophobia;\n7. Uncontrolled medical conditions including hypertension, diabetes mellitus and unstable angina;\n8. Major depression and a history of psychotic disorders;\n9. Terminal diagnosis with life expectancy \\\u003C=1 year.","ALL","21 Years","80 Years",{"count":58,"type":59},50,"ESTIMATED","INTERVENTIONAL",[62],"NA","This study is testing whether a special type of brain stimulation called neuronavigated TMS can help reduce tinnitus (ringing in the ears). 50 people with tinnitus will each receive 20 treatment sessions - 10 real treatments and 10 sham treatments in random order, with a 2-week break between them. Before starting, participants get an MRI brain scan to guide where the stimulation device is placed. Questionnaires of measuring tinnitus severity will be asked four times throughout the study to determine to check the effect of TMS on treating tinnitus.",[65],"Tinnitus","2026-02-20",{"date":68,"type":69},"2026-02-27","ACTUAL",{"date":71,"type":69},"2025-11-01",{"date":73,"type":59},"2027-10-30",{"name":5,"class":6},1]