[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100498790":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":10,"locations":18,"responsibleParty":45,"collaborators":47,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":10,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":20,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Istituti Clinici Scientifici Maugeri SpA","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"All healthy participants",null,"All healthy participants will undergo behavioral assessment and fMRI",[13],"Other: No intervention",[15],{"type":6,"name":16,"description":16,"armGroupLabels":17,"otherNames":10},"No intervention",[9],[19],{"facility":5,"status":20,"city":21,"state":22,"zip":23,"country":24,"countryCode":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":32},"RECRUITING","Pavia","Ita","27100","Italy","IT",{"type":27,"coordinates":28},"Point",[29,30],9.15917,45.19205,{"lat":30,"lon":29},[33,38,42],{"name":34,"role":35,"phone":36,"phoneExt":10,"email":37},"Nicola Canessa, Canessa","CONTACT","+390382375845","nicola.canessa@icsmaugeri.it",{"name":39,"role":35,"phone":40,"phoneExt":10,"email":41},"Tiziana Bachetti","+390382593210","tiziana.bachetti@icsmaugeri.it",{"name":43,"role":44,"phone":10,"phoneExt":10,"email":10},"Nicola Canessa, PhD","PRINCIPAL_INVESTIGATOR",{"type":46,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[48],{"name":49,"class":6},"Istituto Universitario di Studi Superiori Pavia","100498790","neural-bases-of-decision-making-in-healthy-individuals-100498790",false,"NCT05774834","Neural Bases of Decision-making in Healthy Individuals","A Non-interventional Functional Magnetic Resonance Imaging (fMRI) Study on the Neural Bases of Decision-making in Healthy Individuals","Inclusion Criteria:\n\n* Healthy participants, as determined by screening assessments and principal investigator judgment\n* The participant must be able to comply with study requirements as judged by the principal investigator\n\nExclusion Criteria:\n\n* Any history of alcohol and\u002For drug abuse, addiction or suspicion of regular consumption of drugs of abuse\n* Use of any psychoactive medication, or medications known to have effect on central nervous system (CNS) or blood flow\n* Any contraindications for magnetic resonance imaging (MRI) scans or any brain\u002Fhead abnormalities restricting MRI eligibility","ALL","18 Years","60 Years",{"count":61,"type":62},150,"ESTIMATED","OBSERVATIONAL","The goal of this single center non-interventional fMRI study is to assess the neural bases of decision-making and executive functioning in healthy individuals,and whether\u002Fhow their responsiveness is modulated by ageing. The main questions it aims to answer are:\n\n1. are there specific neural correlates for ageing effects on executive functioning (particularly inhibitory control) and decision-making?\n2. Is there a relationship, at the behavioral and neural levels, between ageing-related changes in executive functioning and decision-making?\n\nHealthy participants will be recruited for\n\n1. a behavioral assessment including multiple tests of decision-making and executive functioning\u002Finhibitory control;\n2. a fMRI session to collect data concerning a) brain activity associated with decision-making and executive functioning, b) brain structural morphometriy (grey-matter volume\u002Fdensity), and c) brain structural connectivity (diffusion weighted imaging).\n\nResults will provide an useful baseline for investigating alterations of decision-making and executive functioning, and of their neural bases, in pathological conditions.",[66],"Healthy Volunteers",[68,69,70,71],"decision-making","executive functioning","fMRI","ageing","2026-05-04",{"date":74,"type":75},"2026-05-08","ACTUAL",{"date":77,"type":75},"2018-11-10",{"date":79,"type":62},"2027-10-31",{"name":5,"class":6},1]