[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100498792":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":10,"locations":18,"responsibleParty":44,"collaborators":46,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":10,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":10,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":20,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Istituti Clinici Scientifici Maugeri SpA","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"All healthy participants",null,"All healthy participants will undergo behavioral assessment and fMRI or EEG",[13],"Other: No intervention",[15],{"type":6,"name":16,"description":16,"armGroupLabels":17,"otherNames":10},"No intervention",[9],[19],{"facility":5,"status":20,"city":21,"state":22,"zip":23,"country":24,"countryCode":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":32},"RECRUITING","Pavia","Ita","27100","Italy","IT",{"type":27,"coordinates":28},"Point",[29,30],9.15917,45.19205,{"lat":30,"lon":29},[33,38,42],{"name":34,"role":35,"phone":36,"phoneExt":10,"email":37},"Nicola Canessa, PhD","CONTACT","+390382375845","nicola.canessa@icsmaugeri.it",{"name":39,"role":35,"phone":40,"phoneExt":10,"email":41},"Tiziana Bachetti","+390382593210","tiziana.bachetti@icsmaugeri.it",{"name":34,"role":43,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":45,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[47],{"name":48,"class":6},"Istituto Universitario di Studi Superiori Pavia","100498792","neural-bases-of-social-cognitive-processing-in-healthy-individuals-100498792",false,"NCT05774860","Neural Bases of Social Cognitive Processing in Healthy Individuals","A Non-interventional Functional Magnetic Resonance Imaging (fMRI) and ElectroEncephalography (EEG) Study on the Neural Bases of Social Cognitive Processing in Healthy Individuals","Inclusion Criteria:\n\n* Healthy participants, as determined by screening assessments and principal investigator judgment\n* The participant must be able to comply with study requirements as judged by the principal investigator\n\nExclusion Criteria:\n\n* Any history of alcohol and\u002For drug abuse, addiction or suspicion of regular consumption of drugs of abuse\n* Use of any psychoactive medication, or medications known to have effect on central nervous system (CNS) or blood flow\n* Any contraindications for magnetic resonance imaging (MRI) scans or any brain\u002Fhead abnormalities restricting MRI eligibility","ALL","18 Years","60 Years",{"count":60,"type":61},200,"ESTIMATED","OBSERVATIONAL","The goal of this single center non-interventional fMRI and EEG study is to assess the neural bases of social cognitive processing in healthy individuals, and whether\u002Fhow their responsiveness is modulated by ageing. The main questions it aims to answer are:\n\n* are there specific brain regions where individual differences in social cognitive performance reflect well-established metrics of social cogntion such as empathy and mentalizing?\n* is there a relationship, at the behavioral and neural levels, between ageing-related changes in social cognitive performance and empathy\u002Fmentalizing?\n\nHealthy participants will be recruited for:\n\n* a behavioral assessment including multiple tests of social cognition focused on empathy and mentalizing;\n* for half participants: a fMRI session to collect data concerning a) brain activity associated with action observation and social cognitive processing, b) brain structural morphometriy (grey-matter volume\u002Fdensity), and c) brain structural connectivity (diffusion weighted imaging)\n* for half participants: a EEG session to collect data concerning brain responsiveness to social cognitive processing with higher temporal resolution than that afforded by fMRI.\n\nResults will provide an useful baseline for investigating alterations of social cognitive processing, and of their neural bases, in pathological conditions.",[65],"Healthy Volunteers",[67,68,69,70,71],"social cognitive processing","empathy","mentalizing","fMRI","ageing","2026-05-04",{"date":74,"type":75},"2026-05-08","ACTUAL",{"date":77,"type":75},"2018-07-14",{"date":79,"type":61},"2027-10-31",{"name":5,"class":6},1]