[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100429603":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":37,"centralContacts":43,"locations":50,"responsibleParty":83,"collaborators":85,"id":91,"slug":92,"hasResults":93,"nctId":94,"briefTitle":95,"officialTitle":95,"acronym":23,"eligibilityCriteria":96,"healthyVolunteers":97,"sex":98,"minAge":99,"maxAge":100,"enrollmentInfo":101,"targetDuration":23,"studyType":104,"phases":105,"briefSummary":107,"conditions":108,"keywords":23,"overallStatus":52,"whyStopped":23,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":119},{"fullName":5,"class":6},"Duke University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"RNS Participants","EXPERIMENTAL","Subjects with RNS implants.",[13,14,15,16],"Device: Deep Brain Stimulation","Behavioral: Memory and spatial navigation tasks","Behavioral: Physiological Signals","Behavioral: Questionnaires and Assessments",[18,24,29,33],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"DEVICE","Deep Brain Stimulation","Deep brain stimulation will be used",[9],null,{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":23},"BEHAVIORAL","Memory and spatial navigation tasks","Tasks may include walking around the room, on a treadmill, or in a controlled environment using VR (virtual reality) or AR (augmented reality) technology designed to simulate real-world navigation. Participants may also use Meta Ray-Ban glasses to capture new memories while recording neural activity.",[9],{"type":25,"name":30,"description":31,"armGroupLabels":32,"otherNames":23},"Physiological Signals","Physiological signals such as heart rate, respiration, and skin conductance will be monitored while completing lab tasks. Motion capture and eye-tracking may also be used.",[9],{"type":25,"name":34,"description":35,"armGroupLabels":36,"otherNames":23},"Questionnaires and Assessments","Participants complete questionnaires and assessments to assess subjective emotional experience.",[9],[38,42],{"name":39,"affiliation":40,"role":41},"Nanthia Suthana, PhD","University of California, Los Angeles","PRINCIPAL_INVESTIGATOR",{"name":39,"affiliation":5,"role":41},[44,49],{"name":45,"role":46,"phone":47,"phoneExt":23,"email":48},"Gabriela Vilchez","CONTACT","9196812577","suthanalab@duke.edu",{"name":39,"role":46,"phone":47,"phoneExt":23,"email":48},[51,70],{"facility":40,"status":52,"city":53,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"RECRUITING","Los Angeles","California","90024","United States","US",{"type":59,"coordinates":60},"Point",[61,62],-118.24368,34.05223,{"lat":62,"lon":61},[65,69],{"name":66,"role":46,"phone":67,"phoneExt":23,"email":68},"Sonja Hiller","310-794-7517","shiller@mednet.ucla.edu",{"name":39,"role":41,"phone":23,"phoneExt":23,"email":23},{"facility":5,"status":52,"city":71,"state":72,"zip":73,"country":56,"countryCode":57,"cosmosGeoPoint":74,"geoPoint":78,"contacts":79},"Durham","North Carolina","27705",{"type":59,"coordinates":75},[76,77],-78.89862,35.99403,{"lat":77,"lon":76},[80,82],{"name":45,"role":46,"phone":81,"phoneExt":23,"email":48},"919-681-2577",{"name":39,"role":41,"phone":23,"phoneExt":23,"email":23},{"type":84,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR",[86,89],{"name":87,"class":88},"National Institute of Neurological Disorders and Stroke (NINDS)","NIH",{"name":90,"class":88},"National Institute of Mental Health (NIMH)","100429603","neural-correlates-of-real-world-spatial-navigation-in-humans-100429603",false,"NCT04874220","Neural Correlates of Real World Spatial Navigation in Humans","Inclusion Criteria:\n\n* 12 years of age or older and has undergone RNS system placement\n* Willing to provide informed consent and participate the study\n* Ability to read and write English fluently\n\nExclusion Criteria:\n\n* Unwilling to provide informed consent",true,"ALL","12 Years","70 Years",{"count":102,"type":103},70,"ESTIMATED","INTERVENTIONAL",[106],"NA","The purpose of this study is to understand the neural mechanisms that support real world spatial navigation in humans using deep brain recordings and stimulation during virtual reality (VR), augmented reality, and real world memory tasks. We will determine the cognitive (i.e., memory) and behavioral (i.e., body, head, eye position and movement) factors that modulate deep brain activity and the consequent effects of memory-enhancing deep brain stimulation.",[109],"Memory, Delayed","2026-05-13",{"date":112,"type":113},"2026-05-15","ACTUAL",{"date":115,"type":113},"2020-09-30",{"date":117,"type":103},"2026-06-30",{"name":5,"class":6},2]