[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100533262":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":33,"responsibleParty":51,"collaborators":54,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":20,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":20,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":78,"overallStatus":36,"whyStopped":20,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Anglia Ruskin University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Music intervention","EXPERIMENTAL","Music-based exercises for arm\u002Fhand coordination, range of movement and dexterity using a selection of hand percussion, stand-mounted percussion and tablet with touchscreen instruments.",[13],"Behavioral: Therapeutic Instrumental Music Performance",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BEHAVIORAL","Therapeutic Instrumental Music Performance","Exercises using musical instruments to improve hemiparetic hand and arm function",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Alexander J Street, PhD","PRINCIPAL_INVESTIGATOR",[26,30],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":29},"CONTACT","07799392838","alex.street@anglia.ac.uk",{"name":31,"role":27,"phone":20,"phoneExt":20,"email":32},"Clemens Maidhof, PhD","clemens.maidhof@aru.ac.uk",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":20,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Cambridgeshire COmmunity Services NHS Trust","RECRUITING","Bedford","Bedfordshire","United Kingdom","UK",{"type":42,"coordinates":43},"Point",[44,45],-0.46632,52.13459,{"lat":45,"lon":44},[48],{"name":49,"role":27,"phone":20,"phoneExt":20,"email":50},"Paula Waddingham, PhD","paula.waddingham@nhs.net",{"type":24,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Alex Street","Senior Research Fellow (Music therapy)",[55],{"name":56,"class":6},"Cambridgeshire Community Services NHS Trust","100533262","neural-mechanisms-of-music-intervention-chronic-arm-hemiparesis-following-stroke-a-single-case-series-eeg-study-100533262",false,"NCT06223529","Neural Mechanisms of Music Intervention Chronic Arm Hemiparesis Following Stroke: A Single Case Series EEG Study","The Neural Mechanisms of Music Intervention for Chronic Arm Hemiparesis Following Stroke: A Single Case Series EEG Study","Inclusion Criteria:\n\n1. Aged 18+\n2. Ischemic stroke\n3. Three weeks to 60 months post-stroke\n4. 12 to 49\u002F57 Action Research Arm Test (ARAT) score \\*\n5. Able to follow instructions and consent\n6. Right-hand dominant\n\nExclusion Criteria:\n\n1. Hemorrhagic stroke\n2. No movement in arm\n3. Unable to move thumb and one finger. Loss of sensation and proprioceptive impairment will not lead to exclusion.\n4. Unable to consent to participate\n5. Currently receiving music therapy\n6. Left-hand dominant\n7. Ambidextrous\n8. Not registered with a GP. We will require GP details to inform them in case of any incidental findings in the EEG.","ALL","18 Years","110 Years",{"count":68,"type":69},5,"ESTIMATED","INTERVENTIONAL",[72],"NA","The aims of the study are to recruit five participants with stroke upper limb hemiparesis and determine the effects on neural reorganisation of a three-week music intervention using electroencephalogram measures.\n\nSecondly, the researchers will measure for changes in arm function before and after the three-week music intervention.\n\nThis is a single-arm pre-\u002Fpost experiment\n\nPrimary research questions:\n\nWhat are the neuroplastic changes induced by Therapeutic Instrumental Music Performance (TIMP)?\n\nSecondary research questions What are the functional changes in hemiparetic arm and hand induced by TIMP?\n\nParticipants will be recruited once they have completed their statutory community stroke rehabilitation.\n\nThey will receive 15 X music therapy sessions in their home over three-weeks. Exercises will be delivered by trained clinicians, including music therapists and stroke rehabilitations specialists.\n\nExercises will be facilitated for full range of arm movement, using a range of percussion instruments on stands and handheld, and iPad with touchscreen instruments, which include keyboards and string instruments that can be played using pinch-grip, holding a stylus\u002Fplectrum.\n\nPre-\u002Fpost intervention period EEG recordings will made. Stroke Specific Quality of Life (SSQoL), Action Research Arm Test and nine-hole-peg-test data will be collected from participants in their homes at weeks: 1, 4, 7 and 10.",[75,76,77],"Stroke","Hemiparesis","Home-based",[79,80],"Neurologic Music Therapy","electroencephalography","2024-07-30",{"date":83,"type":84},"2024-07-31","ACTUAL",{"date":86,"type":84},"2024-07-01",{"date":88,"type":69},"2025-05-01",{"name":5,"class":6},1]