[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100436511":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":33,"locations":42,"responsibleParty":76,"collaborators":80,"id":83,"slug":84,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":10,"eligibilityCriteria":89,"healthyVolunteers":85,"sex":90,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":96,"studyType":97,"phases":10,"briefSummary":98,"conditions":99,"keywords":105,"overallStatus":44,"whyStopped":10,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":119},{"fullName":5,"class":6},"Peking University First Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Neuraxial analgesia exposure",null,"For mothers who accept neuraxial labor analgesia, epidural analgesia or combined spinal-epidural analgesia will be provided according to routine practice of each study center.",[13],"Procedure: Neuraxial labor analgesia",{"label":15,"type":10,"description":16,"interventionNames":17},"No neuraxial analgesia exposure","For patients who do not accept neuraxial labor analgesia, analgesics will be prescribed by obstetricians according to routine practice.",[18],"Procedure: No neuraxial labor analgesia",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"PROCEDURE","Neuraxial labor analgesia","Epidural or combined spinal-epidural labor analgesia will be performed according to the routine practice of each study center.",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"No neuraxial labor analgesia","Neuraxial analgesia will not be performed. Analgesics will be prescribed by the obstetricians according to routine practice.",[15],[30],{"name":31,"affiliation":5,"role":32},"Dong-Xin Wang, MD,PHD","PRINCIPAL_INVESTIGATOR",[34,38],{"name":31,"role":35,"phone":36,"phoneExt":10,"email":37},"CONTACT","86-13910731903","wangdongxin@hotmail.com",{"name":39,"role":35,"phone":40,"phoneExt":10,"email":41},"Ting Ding, MD","86-13718803529","athenading01@hotmail.com",[43,63],{"facility":5,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"RECRUITING","Beijing","Beijing Municipality","100034","China","CN",{"type":51,"coordinates":52},"Point",[53,54],116.39723,39.9075,{"lat":54,"lon":53},[57,60],{"name":58,"role":35,"phone":59,"phoneExt":10,"email":37},"Dong-Xin Wang, MD, PHD","+8610-83572784",{"name":39,"role":35,"phone":61,"phoneExt":10,"email":62},"13718803529","athena_d@sina.com",{"facility":64,"status":44,"city":65,"state":66,"zip":67,"country":48,"countryCode":49,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"Shenzhen Maternity and Child Healthcare Hospital","Shenzhen","Guangdong","518100",{"type":51,"coordinates":69},[70,71],114.0683,22.54554,{"lat":71,"lon":70},[74],{"name":75,"role":35,"phone":10,"phoneExt":10,"email":10},"Yuantao Li, MD",{"type":77,"investigatorFullName":78,"investigatorTitle":79,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Dong-Xin Wang","Professor and Chairman, Department of Anesthesiology and Critical Care Medicine",[81],{"name":82,"class":6},"Shenzhen Maternity & Child Healthcare Hospital","100436511","neuraxial-labor-analgesia-and-offspring-neurodevelopment-100436511",false,"NCT04964206","Neuraxial Labor Analgesia and Offspring Neurodevelopment","Impact of Maternal Neuraxial Labor Analgesia on Offspring Neurodevelopment. A Multicenter, Prospective, Longitudinal Cohort Study","Inclusion Criteria:\n\n1. Primiparae between 18 and 35 years of age with term single cephalic pregnancy;\n2. Undergo regular prenatal examination in the study centers;\n3. Preparing to deliver vaginally.\n\nExclusion Criteria:\n\n1. History of psychiatric diseases (indicate those that are diagnosed before or during pregnancy by psychiatrists);\n2. History of diseases involving the hypothalamic-pituitary-adrenal axis;\n3. Presence of contraindications to epidural analgesia, which includes: (1) History of infectious disease of the central nervous system (poliomyelitis, cerebrospinal meningitis, encephalitis, etc.); (2) History of spinal or intra-spinal disease (trauma or surgery of spinal column, intra-spinal canal mass, etc.); (3) Systemic infection (sepsis); (4) Skin or soft tissue infection at the site of epidural puncture; (5) Coagulopathy.\n4. Presence of contraindications to vaginal delivery;\n5. Other reasons that are considered unsuitable for study participation.","FEMALE","18 Years","35 Years",{"count":94,"type":95},4645,"ESTIMATED","24 Months","OBSERVATIONAL","How perinatal factors affect the long-term development of children has always been an issue of much concern. This study is designed to explore the potential impact of maternal neuraxial labor analgesia exposure on offspring neurodevelopment.",[100,101,102,103,104],"Pregnant Women","Labor Pain","Analgesia, Epidural","Infants","Neurodevelopmental Disorders",[106,107,108,103,109],"Pregnant women","Labor pain","Neuraxial labour analgesia","Neurodevelopmental disorders","2026-06-05",{"date":112,"type":113},"2026-06-09","ACTUAL",{"date":115,"type":113},"2022-10-14",{"date":117,"type":95},"2028-12",{"name":78,"class":6},2]