[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608245":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":17,"centralContacts":21,"locations":7,"responsibleParty":26,"collaborators":7,"id":29,"slug":30,"hasResults":31,"nctId":32,"briefTitle":33,"officialTitle":34,"acronym":7,"eligibilityCriteria":35,"healthyVolunteers":36,"sex":37,"minAge":38,"maxAge":39,"enrollmentInfo":40,"targetDuration":7,"studyType":43,"phases":7,"briefSummary":44,"conditions":45,"keywords":49,"overallStatus":54,"whyStopped":7,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":7},{"fullName":5,"class":6},"Başakşehir Çam & Sakura City Hospital","OTHER_GOV",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":13},"OTHER","Neuro-Mimic Observation Protocol","Observation of eyelid reflex, eye movements, and pupil responses at three standardized intraoperative time points (after induction, during skin incision, and mid-surgery). Parameters will be recorded alongside BIS values without any intervention, device application, or additional risk to patients.",[14,15,16],"Eyelid Reflex Monitoring","Eye Movement Observation","Pupil Diameter Assessment",[18],{"name":19,"affiliation":5,"role":20},"Emine Ozcan, MD","PRINCIPAL_INVESTIGATOR",[22],{"name":19,"role":23,"phone":24,"phoneExt":7,"email":25},"CONTACT","+905301592856","dr.emine3419@gmail.com",{"type":20,"investigatorFullName":27,"investigatorTitle":28,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Emine OZCAN","Principal Investigator","100608245","neuro-mimic-indicators-of-anesthesia-depth-during-general-anesthesia-100608245",false,"NCT07199049","Neuro-Mimic Indicators of Anesthesia Depth During General Anesthesia","Monitoring Eyelid Reflex, Eye Movements, and Pupil Responses in Patients Undergoing General Anesthesia: Neuro-Mimic Indicators of Anesthesia Depth","Inclusion Criteria:\n\n* The study will include patients aged 18-65 who will undergo elective abdominal surgery (e.g., cholecystectomy\u002Fgastrectomy\u002Fcolorectal surgery\u002Fprostatectomy\u002Fhysterectomy, etc.) under general anesthesia, with a planned duration of 1-3 hours.\n* Patients whose eye area is left uncovered and who are in a position suitable for observation\n* Patients who have signed the informed consent form\n* Patients with an ASA score of I-III\n\nExclusion Criteria:\n\n* Patients undergoing surgical procedures in the head, neck, or face region (e.g., ENT, eye, jaw surgery, neurosurgery, thyroid\u002Fparathyroid)\n* Patients whose eye area must be completely covered with a sterile drape\n* Patients with an ASA score of IV or higher\n* Individuals with neurological disorders and impaired pupil response, patients who have previously undergone eye trauma or surgery and cannot undergo pupil evaluation\n* Patients who are unable to communicate and cannot provide informed consent\n* Emergency surgeries (e.g., appendectomy\u002Fileus\u002Fgastrointestinal perforation\u002Fcesarean section\u002Fgunshot wounds\u002Fstab wounds\u002Fmultiple trauma\u002Ftraffic accidents, etc.)\n* Individuals who have previously been included in this study (to prevent repeated inclusion)",true,"ALL","18 Years","65 Years",{"count":41,"type":42},60,"ESTIMATED","OBSERVATIONAL","This prospective observational study will evaluate neuro-mimic indicators of anesthesia depth, including eyelid reflex, eyeball movements, and pupil responses, in patients undergoing elective surgery under general anesthesia. Sixty adult patients will be observed at three standardized time points: after induction, during skin incision, and mid-surgery. All parameters will be recorded alongside bispectral index (BIS) monitoring. The study aims to determine whether these observable signs correlate with anesthesia depth, contribute to early detection of intraoperative awareness, and provide a basis for developing non-invasive depth monitoring systems.",[46,47,48],"General Anesthesia","Intraoperative Awareness","Eye Movements",[50,51,52,48,53],"Anesthesia, General","Awareness, Intraoperative","Pupillary Reflex","Reflex, Blink (Eyelid Reflex)","NOT_YET_RECRUITING","2026-02-04",{"date":57,"type":58},"2026-02-05","ACTUAL",{"date":60,"type":42},"2026-02-03",{"date":62,"type":42},"2026-07-28",{"name":5,"class":6}]