[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100504211":3},{"organization":4,"armGroups":7,"interventions":31,"overallOfficials":10,"centralContacts":36,"locations":42,"responsibleParty":58,"collaborators":10,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":10,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":10,"studyType":75,"phases":10,"briefSummary":76,"conditions":77,"keywords":10,"overallStatus":44,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"The Mind Research Network","OTHER",[8,13,16,19,22,25,28],{"label":9,"type":10,"description":10,"interventionNames":11},"Stimulant Use Severity High",null,[12],"Other: Decision task",{"label":14,"type":10,"description":10,"interventionNames":15},"Stimulant Use Severity Medium",[12],{"label":17,"type":10,"description":10,"interventionNames":18},"Stimulant Use Severity Low",[12],{"label":20,"type":10,"description":10,"interventionNames":21},"Psychopathic Traits High",[12],{"label":23,"type":10,"description":10,"interventionNames":24},"Psychopathic Traits Medium",[12],{"label":26,"type":10,"description":10,"interventionNames":27},"Psychopathic Traits Low",[12],{"label":29,"type":10,"description":10,"interventionNames":30},"Community (Healthy) Controls",[12],[32],{"type":6,"name":33,"description":34,"armGroupLabels":35,"otherNames":10},"Decision task","Participants will complete a simple and\u002For moral decision making functional MRI task.",[29,20,26,23,9,17,14],[37],{"name":38,"role":39,"phone":40,"phoneExt":10,"email":41},"Carla Harenski","CONTACT","505-272-5028","charenski@mrn.org",[43],{"facility":5,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"RECRUITING","Albuquerque","New Mexico","87106","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-106.65114,35.08449,{"lat":54,"lon":53},[57],{"name":38,"role":39,"phone":40,"phoneExt":10,"email":41},{"type":59,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Kent Kiehl","Professor of Psychology, Neuroscience and Law, Executive Science Officer","100504211","neurocognitive-abnormalities-in-stimulant-abuse-among-high-risk-women-100504211",false,"NCT05845333","Neurocognitive Abnormalities in Stimulant Abuse Among High-Risk Women","Inclusion Criteria:\n\n* Biological sex is female\n* Intelligence Quotient 70 or higher\n* Reading level 5th grade or higher\n* Able to speak and understand English\n\nExclusion Criteria:\n\n* Uncorrectable auditory or visual deficits\n* Currently pregnant\n* MRI contraindication\n* Central nervous system disease\n* Current major medical condition\n* Hypertension with complications (e.g., stroke)\n* Diabetes with complications\n* Lifetime history of psychotic disorder\n* Self-report of psychotic disorder (with psychiatric hospitalization) in first degree relative\n* Drug use in past three months\n\n(Healthy controls only):\n\n* History of arrest\n* Substance use beyond light alcohol or marijuana use\n* Currently taking psychotropic medications",true,"FEMALE","18 Years","70 Years",{"count":73,"type":74},334,"ESTIMATED","OBSERVATIONAL","Substance use disorders and psychopathy are serious and costly mental health issues. Psychopathy is known to be associated with aberrant moral decision making and there is considerable interest in determining whether substance use disorders lead to impairments in these same cognitive processes. Recent large-scale research initiatives in forensic settings have begun to identify substance abuse and psychopathy-related disruption in the neural mechanisms involved in moral decision-making processes, and associations between these neural networks and future relapse and antisocial behavior. Here the investigators extend prior work (with incarcerated men) to examine these issues among incarcerated women in order to better understand sex differences. This project addresses the overall lack of neurocognitive research in criminal offenders with substance use disorders, thereby focusing on a major public health issue in an underserved and understudied population.",[78,79],"Stimulant Abuse","Criminal Behavior","2025-05-05",{"date":82,"type":83},"2025-05-08","ACTUAL",{"date":85,"type":83},"2022-08-01",{"date":87,"type":74},"2027-05-31",{"name":5,"class":6},1]