[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100534551":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":26,"locations":32,"responsibleParty":53,"collaborators":55,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":60,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":20,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":20,"overallStatus":35,"whyStopped":20,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"NHS Greater Glasgow and Clyde","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Rheumatoid Arthritis - neurofeedback training","EXPERIMENTAL","Intervention: visual neurofeedback\n\nResearch Assessments\n\n* EEG: relaxed state and motor imagery\n* Quantitative sensory testing\n\nQuestionnaires (after each intervention session):\n\n* visual analog scale - rate pain intensity\n* pain description and pain intensity reporting\n* mental strategies, affects (emotional experience) and sensations during NF\n* adverse event reporting\n* NASA task load index\n\nQuestionnaires (week before and week after intervention weeks)\n\n* Routine Assessment of Patient Index Data 3 (RAPID3)\n* American College of Rheumatology Fibromyalgia Scale (ACRFS)\n* McGill Pain Questionnaire\n* Patient-Reported Outcomes Measurement Information System (PROMIS) Depression\n* PROMIS-Anxiety\n* PROMIS-Fatigue\n* PROMIS-Sleep related impairment\n* Pain Number Rating Scale\n* Generalised Self-Efficiency Scale questionnaire\n* Multidimensional Health Locus of Control Scale questionnaires\n\nRemote follow-up: semi-structured interview over the telephone",[13],"Procedure: Neurofeedback",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","Neurofeedback","A noninvasive method based on the voluntary modulation of brain activity, with feedback provided through a graphical user interface shown on a computer screen",[9],null,[22],{"name":23,"affiliation":24,"role":25},"Neil Basu, MD, PhD","NHS Greater Galsgow and Clyde","PRINCIPAL_INVESTIGATOR",[27],{"name":28,"role":29,"phone":30,"phoneExt":20,"email":31},"Aleksandra Vuckovic, PhD","CONTACT","+44 7906441955","aleksandra.vuckovic@glasgow.ac.uk",[33],{"facility":34,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Clinical Research Facility (CRF), Queen Elizabeth University Hospital","RECRUITING","Glasgow","Scotland","G51 4LS","United Kingdom","UK",{"type":42,"coordinates":43},"Point",[44,45],-4.25763,55.86515,{"lat":45,"lon":44},[48,52],{"name":49,"role":29,"phone":50,"phoneExt":20,"email":51},"Manager","+44141 232 7600","Glasgow.CRF@ggc.scot.nhs.uk",{"name":23,"role":25,"phone":20,"phoneExt":20,"email":20},{"type":54,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR",[56],{"name":57,"class":6},"University of Glasgow","100534551","neurofeedback-for-nociplastic-pain-in-rheumatoid-arthritis-nectar-100534551",false,"NCT06240299","Neurofeedback for Nociplastic Pain in Rheumatoid Arthritis (NECTAR)","Neurofeedback for Nociplastic Pain in Rheumatoid Arthritis","NECTAR","Inclusion Criteria:\n\n* Fulfilment of the ACR\u002FEULAR Classification Criteria for rheumatoid arthritis (RA)\n* Fulfilment of the American College of Rheumatology criteria for chronic widespread pain\n* Stable disease (swollen joint count ≤1 and CRP ≤10)\n* Has normal or corrected to normal vision and hearing abilities\n* Right-handed (to reduce baseline motor response test heterogeneity)\n* Pain intensity equal or larger than 4 on the Visual Numerical Scale (0 no pain, 10, max pain imaginable)\n\nExclusion Criteria:\n\n* Unable to understand the task.\n* Unable to provide a written informed consent.\n* Unable to understand English.\n* Major confounding neurological diseases including Multiple Sclerosis, Stroke, Traumatic Brain Injury, Parkinson's Disease, and Alzheimer's Disease)\n* Medical or psychiatric conditions that in the judgment of study personnel would preclude participation in the study (psychosis, suicidal ideation etc)\n* Under active management of pain team (changing medications, other non pharmacological pain treatment)\n* Involved in other interventional experimental studies","ALL","18 Years","75 Years",{"count":70,"type":71},16,"ESTIMATED","INTERVENTIONAL",[74],"NA","Rheumatoid arthritis is an autoimmune condition, causing inflammation and pain. Yet pain may persist even when inflammation has been treated. This residual pain, called nociplastic pain, has symptoms of a chronic pain condition called fibromyalgia. There are few effective therapies to address this residual pain. Published literature shows that fibromyalgia can be treated by neurofeedback, a noninvasive method that is based on the voluntary modulation of cortical activity. In this pilot study, the investigators want to test the effect of neurofeedback on the fibromyalgia component of pain in rheumatoid arthritis, and also to investigate its effects on related symptoms such as fatigue and sleep disturbance.",[77,78],"Rheumatoid Arthritis","Chronic Widespread Pain","2025-06-11",{"date":81,"type":82},"2025-06-15","ACTUAL",{"date":84,"type":82},"2024-06-24",{"date":86,"type":71},"2027-01-29",{"name":5,"class":6},1]