[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100542155":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":17,"locations":25,"responsibleParty":55,"collaborators":58,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":77,"sex":83,"minAge":7,"maxAge":7,"enrollmentInfo":84,"targetDuration":7,"studyType":87,"phases":7,"briefSummary":88,"conditions":89,"keywords":92,"overallStatus":28,"whyStopped":7,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Monash University","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","Venepuncture","A single blood draw at the time of presentation to clinic or whilst an inpatient.",[14],{"name":15,"affiliation":5,"role":16},"Prof. Amy Brodtmann, MBBS, FRACP, PhD, FANZAN","PRINCIPAL_INVESTIGATOR",[18,22],{"name":15,"role":19,"phone":20,"phoneExt":7,"email":21},"CONTACT","03 9094 9540","amy.brodtmann@monash.edu",{"name":23,"role":19,"phone":7,"phoneExt":7,"email":24},"Svetlana Ivanic, BSc(Hons)","svetlana.ivanic@monash.edu",[26,43],{"facility":27,"status":28,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Box Hill Hospital","RECRUITING","Box Hill","Victoria","3128","Australia","AU",{"type":35,"coordinates":36},"Point",[37,38],145.12545,-37.81887,{"lat":38,"lon":37},[41],{"name":42,"role":19,"phone":7,"phoneExt":7,"email":24},"Svetlana Ivanic",{"facility":44,"status":28,"city":45,"state":30,"zip":46,"country":32,"countryCode":33,"cosmosGeoPoint":47,"geoPoint":51,"contacts":52},"Wantirna Health","Wantirna","3152",{"type":35,"coordinates":48},[49,50],145.21667,-37.85,{"lat":50,"lon":49},[53],{"name":54,"role":19,"phone":7,"phoneExt":7,"email":7},"Sarah Shue",{"type":16,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Amy Brodtmann","Professor",[59,61,63,65,67,69,72],{"name":60,"class":6},"Eastern Health",{"name":62,"class":6},"University of Melbourne",{"name":64,"class":6},"Wake Forest University",{"name":66,"class":6},"Deakin University",{"name":68,"class":6},"The Florey Institute of Neuroscience and Mental Health",{"name":70,"class":71},"Invitae Corporation","INDUSTRY",{"name":73,"class":74},"Redenlab","UNKNOWN","100542155","neurofilament-light-chain-and-voice-acoustic-analyses-in-dementia-diagnosis-100542155",false,"NCT06339190","Neurofilament Light Chain And Voice Acoustic Analyses In Dementia Diagnosis","A Blood Test for Dementia? A Cohort Study to Assess the Diagnostic Utility of Plasma Neurofilament Light Chain Protein in All-cause Dementia","NAVAIDD","Inclusion Criteria:\n\n* All patients presenting to Eastern Health services with a cognitive complaint or potential neurodegenerative disorder\n\nExclusion Criteria:\n\n* Prognosis \\\u003C12 months\n* No cognitive complaint\n* Patients not involved within the single healthcare network","ALL",{"count":85,"type":86},1000,"ESTIMATED","OBSERVATIONAL","This cohort study aims to determine if a blood test can aid with diagnosing dementia in anyone presenting with cognitive complaints to a single healthcare network. The investigators will measure levels of a brain protein, Neurofilament light chain (Nfl), and assess changes in language using speech tests.\n\nParticipants will have a single blood test and speech test, and will be followed up at 12-months to complete questionnaires and cognitive scales over the phone. The speech test will also be completed again at 12-months.\n\nIndividuals at risk of a Fronto-temporal dementia syndrome will be eligible to complete optional genetic testing involving an 'at home' saliva sample.",[90,91],"Neurodegenerative Diseases","Dementia",[93,91,94,95,96,97,98],"Alzheimer's disease","Neurofilament light chain","Speech","Neurodegeneration","Biomarker","Health care disparity","2025-05-29",{"date":101,"type":102},"2025-05-30","ACTUAL",{"date":104,"type":102},"2021-08-01",{"date":106,"type":86},"2027-12",{"name":5,"class":6},2]