[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100571602":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":46,"centralContacts":47,"locations":53,"responsibleParty":76,"collaborators":46,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":84,"acronym":46,"eligibilityCriteria":85,"healthyVolunteers":86,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":46,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":99,"overallStatus":56,"whyStopped":46,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"University of Texas, El Paso","OTHER",[8,14,20,25],{"label":9,"type":10,"description":11,"interventionNames":12},"Control","PLACEBO_COMPARATOR","Participants will receive stimulation only up to sensory level.",[13],"Device: Neuromuscular Electrical Stimulation (Sensory)",{"label":15,"type":16,"description":17,"interventionNames":18},"NMES","EXPERIMENTAL","Participants will receive stimulation up to maximum tolerable level.",[19],"Device: Neuromuscular Electrical Stimulation",{"label":21,"type":10,"description":22,"interventionNames":23},"Resistance Training","Participants will receive exercise training with stimulation up to sensory level.",[13,24],"Other: Resistance Training",{"label":26,"type":16,"description":27,"interventionNames":28},"Resistance Training + NMES","Participants will receive exercise training with stimulation up to maximum tolerable intensity.",[19,24],[30,36,42],{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"DEVICE","Neuromuscular Electrical Stimulation (Sensory)","Group will receive Electrical Stimulation up to sensory level",[9,21],[9],{"type":31,"name":37,"description":38,"armGroupLabels":39,"otherNames":40},"Neuromuscular Electrical Stimulation","Group will receive Electrical Stimulation up to maximum tolerable level",[15,26],[41],"NMES Group",{"type":6,"name":21,"description":43,"armGroupLabels":44,"otherNames":45},"Group will receive exercise training.",[21,26],[9],null,[48],{"name":49,"role":50,"phone":51,"phoneExt":46,"email":52},"Sudip Bajpeyi, PhD","CONTACT","9157475461","sbajpeyi@utep.edu",[54],{"facility":55,"status":56,"city":57,"state":58,"zip":59,"country":60,"countryCode":61,"cosmosGeoPoint":62,"geoPoint":67,"contacts":68},"University of Texas at El Paso","RECRUITING","El Paso","Texas","79968","United States","US",{"type":63,"coordinates":64},"Point",[65,66],-106.48693,31.75872,{"lat":66,"lon":65},[69,71,74],{"name":49,"role":50,"phone":70,"phoneExt":46,"email":52},"915-747-5461",{"name":72,"role":73,"phone":46,"phoneExt":46,"email":46},"Zahra Fatahimeiabadi, B.S.","SUB_INVESTIGATOR",{"name":75,"role":73,"phone":46,"phoneExt":46,"email":46},"Jehu N Apaflo, MS",{"type":77,"investigatorFullName":78,"investigatorTitle":79,"investigatorAffiliation":5,"oldNameTitle":46,"oldOrganization":46},"PRINCIPAL_INVESTIGATOR","Sudip Bajpeyi","Professor","100571602","neuromuscular-electrical-stimulation-a-novel-treatment-for-improving-metabolism-100571602",false,"NCT06722391","Neuromuscular Electrical Stimulation: A Novel Treatment for Improving Metabolism","Inclusion Criteria:\n\n* Overweight\u002FObese (BMI ≥25)\n* Sedentary Lifestyle: Physical Activity Level\\<1.4\n* Less than 150min\u002Fweek of structured Exercise\n\nExclusion Criteria:\n\n* Use of anti-hypertensive, lipid-lowering or insulin sensitizing medications\n* Excessive alcohol, drug abuse, smoking\n* Pregnant Women\n* Unwilling to adhere to the study Intervention",true,"ALL","18 Years","65 Years",{"count":91,"type":92},80,"ESTIMATED","INTERVENTIONAL",[95],"NA","Once written consent is obtained, the participant will be provided with an accelerometer to be worn for 7 days to assess current physical activity levels. Subjects will be provided with a standardized diet (55\u002F15\u002F30% CHO\u002FPRO\u002FFAT) prior to collection of pre-intervention data of insulin sensitivity. Individuals will then participate in an 8-week electrical stimulation intervention (30min\u002Fday, 3x\u002Fweek) and randomized into placebo\u002Fcontrol, NMES, resistance training combined with NMES (RT +NMES), or resistance training (RT) group (n=20 per group), followed by collection of post-intervention data. The control group will receive electrical stimulation up to sensory level, the NMES group will receive stimulation up to tolerable intensity to induce visible muscle contraction, the RT+ NMES will receive stimulation up to tolerable intensity during resistance training, and the RT group will only receive exercise training. Control and NMES group will self administer stimulation at home. Pre-and post-intervention data includes measurements for body composition, resting metabolic rate, VO2max, insulin sensitivity, and comprehensive blood work.",[98],"Insulin Resistance",[37,100,101,102,103],"Glucose Continuous Monitor","Blood Glucose","Obesity","Resting Metabolic rate","2024-12-03",{"date":106,"type":107},"2024-12-09","ACTUAL",{"date":109,"type":107},"2024-08-19",{"date":111,"type":92},"2031-09-01",{"name":5,"class":6},1]