[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560170":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":40,"responsibleParty":65,"collaborators":26,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":26,"eligibilityCriteria":73,"healthyVolunteers":74,"sex":75,"minAge":76,"maxAge":26,"enrollmentInfo":77,"targetDuration":26,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":90,"overallStatus":42,"whyStopped":26,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"The Hong Kong Polytechnic University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Perturbation-based balance training group","EXPERIMENTAL","This group will receive two sessions of treadmill walking at their comfortable speed involving perturbations",[13],"Behavioral: Perturbation-based balance training (PBT)",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","PLACEBO_COMPARATOR","This group will receive two sessions of treadmill walking at their comfortable speed involving no perturbations",[19],"Behavioral: Walking exercise (control)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Perturbation-based balance training (PBT)","It will be a two-session training with each session lasting for approximately an hour. Perturbations will be induced during treadmill walking. Participants will be instructed to recover their balance and continue walking after the perturbations.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Walking exercise (control)","It will be a two-session training with each session lasting for approximately an hour. The same training duration and format will be used as the PBT group, except that no perturbations will be induced during the treadmill walking.",[15],[32],{"name":33,"affiliation":5,"role":34},"Sau Lan Tsang, PhD","PRINCIPAL_INVESTIGATOR",[36],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","852 3400 8965","charlotte-sl.tsang@polyu.edu.hk",[41],{"facility":5,"status":42,"city":43,"state":26,"zip":26,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","Hong Kong","HK",{"type":46,"coordinates":47},"Point",[48,49],114.17469,22.27832,{"lat":49,"lon":48},[52,53,54,57,59,61,63],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},{"name":33,"role":34,"phone":26,"phoneExt":26,"email":26},{"name":55,"role":56,"phone":26,"phoneExt":26,"email":26},"Georg Kranz, PhD","SUB_INVESTIGATOR",{"name":58,"role":56,"phone":26,"phoneExt":26,"email":26},"Thomson Wong, PhD",{"name":60,"role":56,"phone":26,"phoneExt":26,"email":26},"Roy Cheung, PhD",{"name":62,"role":56,"phone":26,"phoneExt":26,"email":26},"Timothy Kwok, MD",{"name":64,"role":56,"phone":26,"phoneExt":26,"email":26},"Shamay Ng, PhD",{"type":66,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100560170","neurophysiological-changes-after-perturbation-based-training-in-older-adults-100560170",false,"NCT06573658","Neurophysiological Changes After Perturbation-based Training in Older Adults","Short-term Neurophysiological Changes After a Perturbation-based Training in Community-dwelling Older Adults: A Pilot Study","Inclusion Criteria:\n\n* Aged ≥ 60 years old\n* Community-dwelling\n* Right-handed\n* Able to communicate effectively in Cantonese or Mandarin\n* Able to walk independently on level ground for ≥ 30 minutes\n* Abbreviated Mental Test (Hong Kong version) score ≥ 6\n\nExclusion Criteria:\n\n* Metal implants (e.g. pacemaker, artificial cochlea)\n* Uncorrected vision or hearing impairment\n* Osteoporosis\n* Hip or knee replacement within the last year\n* Musculoskeletal, cardiovascular, mental, or neurological disorders (such as Parkinson's disease) which can affect MRI examination, balance control, or exercise participation.",true,"ALL","60 Years",{"count":78,"type":79},88,"ESTIMATED","INTERVENTIONAL",[82],"NA","This is an assessor-blinded neurophysiological study. Participants will be randomly assigned to a perturbation-based training (PBT) or a walking (control) group. Changes in postural stability and neurophysiology in the brain following PBT compared to walking exercise without perturbation will be investigated.",[85,86,87,88,89],"Falling","Community Dwelling Older Adults","Postural Stability","Brain Connectivity","Brain Structure",[91,92,93,94,95,96,97,98],"Perturbation","Magnetic Resonance Image","MRI","step training","responsive postural control","balance","external disturbance","fall","2025-09-19",{"date":101,"type":102},"2025-09-24","ACTUAL",{"date":104,"type":102},"2024-04-18",{"date":106,"type":79},"2026-10-14",{"name":5,"class":6},1]