[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100581301":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":24,"locations":29,"responsibleParty":53,"collaborators":24,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":24,"eligibilityCriteria":61,"healthyVolunteers":58,"sex":62,"minAge":63,"maxAge":24,"enrollmentInfo":64,"targetDuration":24,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":24,"overallStatus":32,"whyStopped":24,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"University of Pennsylvania","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Participants without Deep Brain Stimulators","EXPERIMENTAL","Multimodal neurophysiology (for example, electroencephalography and electromyography) will be measured during the following:\n\nMovement disorder medication administration -The patient's movement disorders medications, prescribed by their treating physicians outside of this study, may be administered during an experimental session.",[13],"Other: Prescribed Medications",{"label":15,"type":10,"description":16,"interventionNames":17},"Participants with Deep Brain Stimulators","Multimodal neurophysiology (for example, electroencephalography and electromyography) will be measured during the following:\n\nMovement disorder medication administration -The patient's movement disorders medications, prescribed by their treating physicians outside of this study, may be administered during an experimental session.\n\nDeep brain stimulator (DBS) adjustment - Participants who have had deep brain stimulation implantation as part of their standard-of-care clinical treatment may participate in this study. The patient's stimulator may be adjusted within normal clinical limits during an experimental session.",[13,18],"Other: Deep brain stimulation adjustment",[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Prescribed Medications","participant's movement disorders medications, prescribed by their treating physician",[15,9],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Deep brain stimulation adjustment","Deep brain stimulator parameters may be adjusted within normal clinical limits",[15],[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Pennsylvania Hospital","RECRUITING","Philadelphia","Pennsylvania","19107","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-75.16362,39.95238,{"lat":42,"lon":41},[45,50],{"name":46,"role":47,"phone":48,"phoneExt":24,"email":49},"Charlotte Abeshaus","CONTACT","215-746-4850","Charlotte.Abeshaus@PennMedicine.upenn.edu",{"name":51,"role":52,"phone":24,"phoneExt":24,"email":24},"Lauren Hammer, MD, PhD","PRINCIPAL_INVESTIGATOR",{"type":52,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Lauren Hammer","Assistant Professor of Neurology","100581301","neurophysiology-of-the-basal-ganglia-thalamus-and-cerebellum-in-patients-with-movement-disorders-100581301",false,"NCT06848530","Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement Disorders","Inclusion Criteria:\n\n* Patients 18 years of age and above\n* Any patient who has been diagnosed by a movement disorders neurologist with one of the following movement disorders:\n* Parkinson's disease\n* Dystonia\n* Tremor, including essential tremor\n* Cerebellar ataxia\n* Other hyperkinetic movement disorders, such as chorea and tics\n\nExclusion Criteria:\n\n\\- Patients with dementia","ALL","18 Years",{"count":65,"type":66},100,"ESTIMATED","INTERVENTIONAL",[69],"NA","The research study is being conducted to better understand parts of the human brain called the cortex, basal ganglia, thalamus, and cerebellum in patients with movement disorders (such as Parkinson's disease, essential tremor, dystonia, or ataxia). These brain structures are involved in movement disorders. This study attempts to better understand the brain electrical activity associated with these disorders, both in patients with and without deep brain stimulation (DBS). Recordings are made from the scalp with a noninvasive electrode and\u002For through the DBS stimulator if the participant has a stimulator model that is able to sense brain activity. These recordings are analyzed along with measures of movement disorder symptoms to identify brain signal signatures of symptoms.",[72],"Movement Disorders","2026-03-08",{"date":75,"type":76},"2026-03-11","ACTUAL",{"date":78,"type":76},"2025-12-10",{"date":80,"type":66},"2030-04",{"name":5,"class":6},1]