[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609485":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":16,"locations":25,"responsibleParty":40,"collaborators":10,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":10,"enrollmentInfo":51,"targetDuration":10,"studyType":54,"phases":10,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":65,"whyStopped":10,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"University of Oxford","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Adults with acquired brain injury",null,"We will follow adults with either stroke or traumatic brain injury for one year post-injury to examine the associations between sleep, mental health and motor recovery.",[13],{"name":14,"affiliation":5,"role":15},"Melanie Fleming, PhD","PRINCIPAL_INVESTIGATOR",[17,21],{"name":14,"role":18,"phone":19,"phoneExt":10,"email":20},"CONTACT","00 44 1865 611 461","melanie.fleming@ndcn.ox.ac.uk",{"name":22,"role":18,"phone":23,"phoneExt":10,"email":24},"Brent Elliott, MBBBS MSc","00 44 7967 418523","brent.elliott@keble.ox.ac.uk",[26],{"facility":27,"status":10,"city":28,"state":10,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Wellcome Centre for Integrative Neuroimaging (WIN) FMRIB, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford OX3 9DU","Oxford","OX3 9DU","United Kingdom","UK",{"type":33,"coordinates":34},"Point",[35,36],-1.25596,51.75222,{"lat":36,"lon":35},[39],{"name":14,"role":18,"phone":19,"phoneExt":10,"email":20},{"type":41,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100609485","neuropsychiatric-outcomes-and-disrupted-sleep-following-acquired-brain-injury-100609485",false,"NCT07215195","Neuropsychiatric Outcomes and Disrupted Sleep Following Acquired Brain Injury","NODS","Inclusion Criteria:\n\n* Willing and able to give informed consent for participation in the study.\n* Aged 18 years or above.\n* At least one week, but less than 12 months post-injury\n* Clinical diagnosis of acquired brain injury (stroke, haemorrhage or traumatic).\n* Participants with Traumatic Brain Injury will have a Mild (probable) or Moderate-severe (definite) brain injury according to the Mayo classification\n* Participants must be willing to consent to us contacting their general practitioner (GP) or direct care team if we have concerns about their mental health\n\nExclusion Criteria:\n\n* Brain injury not caused by trauma, haemorrhage or stroke\n* Previous brain injury.\n* Other relevant neurological conditions which could affect outcome measures (e.g., Parkinson's or Alzheimer's disease)\n* No stable and suitable place to sleep","ALL","18 Years",{"count":52,"type":53},150,"ESTIMATED","OBSERVATIONAL","The two most common causes of brain injury are stroke and trauma. Both sleep and mental health problems are common after brain injury; we will investigate whether there is a relationship between poor sleep quality and worse mental health in this group. We will also follow patients up, at approximately three-monthly intervals until one year after injury, to see how sleep and mental health symptoms change over time and with recovery.\n\nWe will assess sleep in detail using questionnaires, a sleep monitor worn on the wrist, a portable brain activity sensor, and a sleep mat. We will assess mental health (neuropsychiatric) symptoms using questionnaires.\n\nParticipants will be asked to complete these assessments at baseline and at approximately 3-monthly intervals until they reach 12 months post-injury.\n\nThis data will allow us to explore the types of sleep disruption seen after brain injury and examine the association between sleep and mental health symptoms.",[57],"Acquired Brain Injury (Including Stroke)",[59,60,61,62,63,64],"stroke","traumatic brain injury","neuropsychiatric disorder","movement","sleep","brain injury","NOT_YET_RECRUITING","2025-10-01",{"date":68,"type":69},"2025-10-10","ACTUAL",{"date":66,"type":53},{"date":72,"type":53},"2027-11-30",{"name":5,"class":6},1]