[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100569032":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":35,"centralContacts":39,"locations":50,"responsibleParty":89,"collaborators":91,"id":95,"slug":96,"hasResults":97,"nctId":98,"briefTitle":99,"officialTitle":100,"acronym":101,"eligibilityCriteria":102,"healthyVolunteers":103,"sex":104,"minAge":105,"maxAge":30,"enrollmentInfo":106,"targetDuration":30,"studyType":109,"phases":110,"briefSummary":112,"conditions":113,"keywords":117,"overallStatus":70,"whyStopped":30,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":129},{"fullName":5,"class":6},"University Hospital, Montpellier","OTHER",[8,15,20],{"label":9,"type":10,"description":11,"interventionNames":12},"patient with early-onset Alzheimer's disease (AD)","EXPERIMENTAL","patients followed up at the Centre Mémoire de Ressources et de Recherche (CMRR) of Montpellier, over 60 with Alzheimer's disease who have cognitive impairment based on an MMSE (Mini Mental State Examination) ≥ 20 and live at home with a relative",[13,14],"Behavioral: neuropsychologist interview","Behavioral: questionnaire",{"label":16,"type":17,"description":18,"interventionNames":19},"patients with parkinson's disease (PD)","ACTIVE_COMPARATOR","patients followed up at the Center Expert Parkinson of Montpellier (CEPMo), over 60 with Parkinson's disease who have cognitive impairment based on an MMSE (Mini Mental State Examination) ≥ 20 and live at home with a relative",[13,14],{"label":21,"type":17,"description":22,"interventionNames":23},"Healthy control","Subjects aged over 60, with no known neurodegenerative disease, living at home with a relative in the Hérault département.",[13,14],[25,31],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"BEHAVIORAL","neuropsychologist interview","It will take place either at the hospital or at the participant's home.\n\nThis interview will consist of :\n\n* socio-demographic data collection\n* neuropsychological tests:\n\n  * MMSE test (Mini Mental State Examination) cognitive function\n  * RL-RI-16 test (16-item free recall\u002Findexed recall test)\n  * BECS test (Semantic knowledge assessment battery )\n  * WCST test (Wisconsin Card Sorting Test )\n  * Musical Cognition Test\n  * Help from the participant's relative to answer certain questions, in particular the MuseEQ-24 questionnaire",[21,9,16],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"questionnaire","The participant answers questionnaires:\n\n* Questionnaire MusEQ-24 self reported (Music Engagement Questionnaire)\n* Questionnaire BMRQ (Barcelona Reward Music Questionnaire)\n* Questionnaire SHAPS (Snaith-Hamilton Pleasure Scale)\n* Questionnaire LARS (Lille's Apathy Rating Scale)\n* Questionnaire PHQ-9 (Patient Health Questionnaire 9 items)",[21,9,16],[36],{"name":37,"affiliation":5,"role":38},"KARIM BENNYS, MD","PRINCIPAL_INVESTIGATOR",[40,46],{"name":41,"role":42,"phone":43,"phoneExt":44,"email":45},"Mikaël Genguelou, PhD","CONTACT","06.04.45.37.94.","+33","mikael.genguelou@univ-montp3.fr",{"name":37,"role":42,"phone":47,"phoneExt":48,"email":49},"04.67.33.72.32","+ 33","k-bennys@chu-montpellier.fr",[51,68,80],{"facility":52,"status":53,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"Montpellier Seniors' Association","NOT_YET_RECRUITING","Montpellier","Hérault","34000","France","FR",{"type":60,"coordinates":61},"Point",[62,63],3.87635,43.61093,{"lat":63,"lon":62},[66],{"name":67,"role":42,"phone":43,"phoneExt":44,"email":45},"Mikaël Guenguelou, PhD",{"facility":69,"status":70,"city":54,"state":55,"zip":71,"country":57,"countryCode":58,"cosmosGeoPoint":72,"geoPoint":74,"contacts":75},"CHU de Montpellier - CEPMo","RECRUITING","34295",{"type":60,"coordinates":73},[62,63],{"lat":63,"lon":62},[76],{"name":77,"role":42,"phone":78,"phoneExt":44,"email":79},"Mahmoud CHARIF, MD","0467337413","m-charif@chu-montpellier.fr",{"facility":81,"status":53,"city":54,"state":55,"zip":71,"country":57,"countryCode":58,"cosmosGeoPoint":82,"geoPoint":84,"contacts":85},"CHU de Montpellier - CMRR",{"type":60,"coordinates":83},[62,63],{"lat":63,"lon":62},[86],{"name":87,"role":42,"phone":88,"phoneExt":44,"email":49},"Karim BENNYS, MD","04.67.33.60.29",{"type":90,"investigatorFullName":30,"investigatorTitle":30,"investigatorAffiliation":30,"oldNameTitle":30,"oldOrganization":30},"SPONSOR",[92],{"name":93,"class":94},"Laboratoire EPSYLON","UNKNOWN","100569032","neuropsychological-profiles-and-musical-engagement-in-parkinsons-and-alzheimers-disease-100569032",false,"NCT06688968","Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease","Observational Pilot Study of Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease. What Are the Effects of Mnestic or Hedonic Impairment on Emotion, Reminiscence and Musical Enjoyment","MUSENGAGE","Inclusion Criteria:\n\nGeneral inclusion criteria:\n\n* 60 years and older\n* French-speaking and volunteering for the study\n* Living at home with a relative\n\nAlzheimer's disease inclusion criteria:\n\n* Biological diagnosis of probable Alzheimer's disease according to NINCDS-ADRDA criteria (McKhann et al., 1984)\n* MMSE greater than or equal to 20\n\nInclusion criteria Parkinson's disease :\n\n* Diagnosis of Idiopathic Parkinson's disease\n* MMSE greater than or equal to 20\n\nExclusion Criteria:\n\n* No known neurological pathologies (epilepsy and other non-degenerative CNS diseases) or psychiatric disorders (chronic psychosis and psychotic episodes)\n* Autistic disorders\n* History of stroke or head trauma\n* Unstable medical condition (cancer)\n* Subject unable to read and\u002For write\n* Hearing impairment without hearing aids\n* Refusal of consent after information\n* Persons unable to give consent, research carried out in emergency situations, etc.)\n* Non-affiliation with a social security scheme\n* Person deprived of liberty (by judicial or administrative decision, or forced hospitalization)\n* Person under legal protection (guardianship, curatorship, legal protection)\n* Person participating in another research project with an exclusion period still in progress",true,"ALL","60 Years",{"count":107,"type":108},120,"ESTIMATED","INTERVENTIONAL",[111],"NA","The goal of this Multicenter observational pilot study is to Compare the specifics of musical engagement (behaviors related to music in everyday life) in subjects aged over 60 with Alzheimer s disease, Parkinson s disease and control subjects.\n\nThe main questions it aims to answer are:\n\n1. The description of different profiles of musical engagement in early-stage AD, in PD and in healthy elderly subjects.\n2. The extent of executive, mnestic and hedonic dysfunctions will impact differently on emotional engagement, autobiographical evocation and sensitivity to musical reward, and will therefore enable distinct profiles to be drawn up.\n\nParticipants will have an intervention consisting of an interview with a neuropsychologist lasting approximately 2 hours, including :\n\n* A semi-structured interview to check the participants eligibility and gather demographic data.\n* Neuropsychological tests and questionnaires will then be administered.\n* A relative of the study participant will help complete questionnaires.",[114,115,116],"Alzheimer Disease, Early Onset","Parkinsons Disease with Dementia","Non Pharmacological Intervention",[118,114,115,119],"Non Pharmacological intervention","Music Therapy","2025-03-14",{"date":122,"type":123},"2025-03-19","ACTUAL",{"date":125,"type":123},"2025-02-04",{"date":127,"type":108},"2025-12-01",{"name":5,"class":6},3]