[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100454209":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":32,"locations":43,"responsibleParty":79,"collaborators":81,"id":84,"slug":85,"hasResults":86,"nctId":87,"briefTitle":88,"officialTitle":88,"acronym":37,"eligibilityCriteria":89,"healthyVolunteers":86,"sex":90,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":37,"studyType":96,"phases":97,"briefSummary":99,"conditions":100,"keywords":102,"overallStatus":46,"whyStopped":37,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"QVITI S.A.","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Real tACS","ACTIVE_COMPARATOR","tACS 75Hz intervention combined with language tasks and breathing exercises. The device will operate in tACS research active stimulation mode.",[13],"Device: tACS",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham tACS","SHAM_COMPARATOR","tACS sham intervention combined with language tasks and breathing exercises. The device will operate in tACS sham simulation research mode.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","tACS","Neurostimulation will be done using the Neuro Device tCS, which is a certified transcranial electrical stimulator. The device consists of a stimulator with a touch screen, two electrodes and a soft, flexible cap to ensure stability of the electrodes on the head.",[9,15],[26],"transcranial alternating current stimulation",[28],{"name":29,"affiliation":30,"role":31},"Miguel Escalon, MD, MPH","Icahn School of Medicine at Mount Sinai","PRINCIPAL_INVESTIGATOR",[33,39],{"name":34,"role":35,"phone":36,"phoneExt":37,"email":38},"Tertia Jeppson","CONTACT","312-238-6163",null,"tjeppson@sralab.org",{"name":40,"role":35,"phone":41,"phoneExt":37,"email":42},"Aidan Rogers","(718) 308-9450","aidan.rogers@mountsinai.org",[44,63],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Think & Speak Lab at Shirley Ryan AbilityLab","RECRUITING","Chicago","Illinois","60611","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-87.65005,41.85003,{"lat":56,"lon":55},[59,61],{"name":60,"role":35,"phone":36,"phoneExt":37,"email":38},"Tertia Jeppson, M.A., CCC-SLP, CBIS",{"name":62,"role":31,"phone":37,"phoneExt":37,"email":37},"Leora Cherney, PhD, CCC-SLP, BC-ANCDS, FACRM",{"facility":64,"status":46,"city":65,"state":65,"zip":66,"country":50,"countryCode":51,"cosmosGeoPoint":67,"geoPoint":71,"contacts":72},"Abilities Research Center at Mount Sinai","New York","10029",{"type":53,"coordinates":68},[69,70],-74.00597,40.71427,{"lat":70,"lon":69},[73,77,78],{"name":74,"role":35,"phone":75,"phoneExt":37,"email":76},"Raphael Kesselman","917-886-4668","raphael.kesselman@mountsinai.org",{"name":40,"role":35,"phone":41,"phoneExt":37,"email":42},{"name":29,"role":31,"phone":37,"phoneExt":37,"email":37},{"type":80,"investigatorFullName":37,"investigatorTitle":37,"investigatorAffiliation":37,"oldNameTitle":37,"oldOrganization":37},"SPONSOR",[82],{"name":30,"class":83},"OTHER","100454209","neurostimulation-for-the-treatment-of-post-stroke-aphasia-100454209",false,"NCT05194566","Neurostimulation for the Treatment of Post-Stroke Aphasia","Individuals with aphasia (assessed using the Boston Diagnostic Aphasia Examination) who perform the Naming Task in the range of 10%-60% accuracy will be included in the study. The overall baseline score in the Naming Task will be estimated from the two baseline measurements.\n\nInclusion Criteria:\n\n* diagnosis of aphasia: Broca's or mixed (based on the assessment of a Speech Language Pathologist).\n* presence of a focus of injury in the left hemisphere (within one hemisphere only) as a result of the first ischemic or hemorrhagic stroke (based on CT\u002FMRI examination);\n* chronic stage of the disease - time since the stroke occurred over 6 months.\n* ability to achieve an accuracy in the Naming Task of 10-60%.\n* 18-80 years\n* right-handedness before the stroke.\n* ability to give informed written consent.\n* fluency in English.\n\nExclusion Criteria:\n\n* severe cognitive, auditory or visual impairment that would preclude cognitive and language testing - inability to follow a two-step command.\n* presence of metal implants in the skull.\n* presence of major untreated or unstable psychiatric disease.\n* history of epilepsy or seizures.\n* ongoing medication that increases the risk of epileptic seizures.\n* presence in the body of cardiac stimulator, pacemaker or vagus nerve stimulator (implanted).\n* history of speech, language, hearing, or intellectual disability during childhood.\n* pregnancy (based on declarations)\n\nExclusion criteria during the trial:\n\n* high intolerance to stimulation.\n* occurrence of an epileptic seizure.\n* other previously absent neurological or mental symptoms\n\nWithdrawal criteria:\n\n* high intolerance to stimulation (participants experience severe discomfort during stimulation);\n* occurrence of an epileptic seizure;\n* other previously absent neurological, physical or mental symptoms.","ALL","18 Years","80 Years",{"count":94,"type":95},64,"ESTIMATED","INTERVENTIONAL",[98],"NA","The aim of the trial is to determine whether 75Hz transcranial alternating current stimulation (tACS) synchronized with therapeutic linguistic tasks is an effective form of therapy for post-stroke aphasia.",[101],"Post-stroke Aphasia",[103,104,105,106],"speech therapy","brain stimulation","communication","language","2026-02-13",{"date":109,"type":110},"2026-02-18","ACTUAL",{"date":112,"type":110},"2023-09-06",{"date":114,"type":95},"2026-12",{"name":5,"class":6},2]