[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100385235":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":23,"locations":33,"responsibleParty":50,"collaborators":10,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":10,"eligibilityCriteria":59,"healthyVolunteers":56,"sex":60,"minAge":10,"maxAge":61,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":10,"overallStatus":35,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Boston Children's Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1",null,"patients who tend to have longer CPB",[13],"Other: Research study",{"label":15,"type":10,"description":16,"interventionNames":17},"Group 2","Patients who have shorter CPB",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Research study","Blood and tracheal aspirates will be collected",[9,15],[24,29],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Sophia Koutsogiannaki, PhD","CONTACT","617-919-4725","sophia.koutsogiannaki@childrens.harvard.edu",{"name":30,"role":26,"phone":31,"phoneExt":10,"email":32},"Koichi Yuki, MD","617-355-6225","koichi.yuki@childrens.harvard.edu",[34],{"facility":5,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Boston","Massachusetts","02115","United States","US",{"type":42,"coordinates":43},"Point",[44,45],-71.05977,42.35843,{"lat":45,"lon":44},[48],{"name":49,"role":26,"phone":10,"phoneExt":10,"email":10},"Rachel Bernier",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Sophia Koutsogiannaki","Assistant Professor","100385235","neutrophil-phenotypic-profiling-and-acute-lung-injury-in-patients-after-cardiopulmonary-bypass-cpb-100385235",false,"NCT04296071","Neutrophil Phenotypic Profiling and Acute Lung Injury in Patients After Cardiopulmonary Bypass (CPB)","Inclusion Criteria:\n\n* Are \\\u003C 12months of age\n* Scheduled for cardiac surgical needing CPB\n* Preoperative SpO2 \\> 90%\n\nExclusion Criteria:\n\n* Lack of parental (or legal guardian's) consent\n* Preoperative SpO2 \\\u003C 90%\n* Preoperative oxygen therapy","ALL","12 Months",{"count":63,"type":64},56,"ESTIMATED","OBSERVATIONAL","Acute lung injury (ALI) following cardiopulmonary bypass (CPB) is a serious complication, often prolonging the length of stay in ICU and potentially dealing to mortality. The objective of this study is to assess the mechanism of CPB-mediated acute lung injury in pediatric patients.",[68,69],"Lung Injury","Cardiopulmonary Bypass","2026-05-13",{"date":72,"type":73},"2026-05-15","ACTUAL",{"date":75,"type":73},"2022-10-14",{"date":77,"type":64},"2027-12",{"name":52,"class":6},1]