[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100598775":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":23,"locations":29,"responsibleParty":46,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":10,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":10,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Istinye University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"PDPH Group",null,"Patients who developed postdural puncture headache (PDPH) following spinal anesthesia for cesarean section.",[13],"Other: PDPH",{"label":15,"type":10,"description":16,"interventionNames":17},"Non-PDPH Group","Patients who did not develop PDPH after spinal anesthesia for cesarean section",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"PDPH","Observational analysis of preoperative inflammatory markers (e.g., NLR, PLR, SIRI) in relation to PDPH development following spinal anesthesia.",[15,9],[24],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"ilke dolgun","CONTACT","+905555485632","ilkeser2004@gmail.com",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":10,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Istinye Üniversity","RECRUITING","Istanbul","Merkez Mahallesi","34250","Turkey (Türkiye)",{"type":38,"coordinates":39},"Point",[40,41],28.94966,41.01384,{"lat":41,"lon":40},[44,45],{"name":25,"role":26,"phone":10,"phoneExt":10,"email":28},{"name":25,"role":26,"phone":10,"phoneExt":10,"email":10},{"type":47,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":50,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","İlke Dolgun","Assoc. prof","Haseki Training and Research Hospital","100598775","neutrophil-to-lymphocyte-ratio-and-postdural-headache-100598775",false,"NCT07075874","Neutrophil to Lymphocyte Ratio and Postdural Headache","Preoperative Neutrophil-to-Lymphocyte Ratio as a Predictor of Post-Dural Puncture Headache Following Cesarean Section Under Spinal Anesthesia","Inclusion Criteria:\n\n* Women aged 18 years or older\n* Underwent elective or emergency cesarean section under spinal anesthesia\n* Had complete preoperative complete blood count (CBC) data available\n* No known hematological or inflammatory disease\n* No intraoperative complications recorded\n* Medical records accessible for postoperative follow-up regarding PDPH symptoms\n\nExclusion Criteria:\n\n* Age under 18\n* Absence of preoperative complete blood count data\n* Presence of hematologic malignancy, active infection, autoimmune disease, or immunosuppressive therapy\n* Platelet count \\\u003C150,000\u002Fmm³ or INR \\>1.5\n* Incomplete or missing medical records","FEMALE","18 Years",{"count":61,"type":62},821,"ESTIMATED","OBSERVATIONAL","This study will aim to investigate whether systemic inflammatory markers-especially the neutrophil-to-lymphocyte ratio (NLR)-obtained from preoperative complete blood counts can predict the development of post-dural puncture headache (PDPH) in obstetric patients undergoing cesarean section under spinal anesthesia.",[66,67],"Preoperative Neutrophil-to-Lymphocyte Ratio (NLR)","Postdural Puncture Headache","2025-07-19",{"date":70,"type":71},"2025-07-24","ACTUAL",{"date":73,"type":71},"2025-07-12",{"date":75,"type":62},"2025-07-17",{"name":5,"class":6},1]